Zobrazeno 1 - 10
of 134
pro vyhledávání: '"John Svaren"'
Autor:
Hye-Jin Park, Eric Tsai, Dennis Huang, Michael Weaver, Luciana Frick, Ace Alcantara, John J. Moran, Julia Patzig, Carmen V. Melendez-Vasquez, Gerald R. Crabtree, M.L. Feltri, John Svaren, Patrizia Casaccia
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104132- (2022)
Summary: Cells elaborate transcriptional programs in response to external signals. In the peripheral nerves, Schwann cells (SC) sort axons of given caliber and start the process of wrapping their membrane around them. We identify Actin-like protein 6
Externí odkaz:
https://doaj.org/article/ed55dc312aef4ee89569512edfbce00b
Autor:
Hongge Wang, Matthew Davison, Kathryn Wang, Tai‐He Xia, Martin Kramer, Katherine Call, Jun Luo, Xingyao Wu, Riccardo Zuccarino, Chelsea Bacon, Yunhong Bai, John J. Moran, Laurie Gutmann, Shawna M. E. Feely, Tiffany Grider, Alexander M. Rossor, Mary M. Reilly, John Svaren, Michael E. Shy
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 1, Pp 69-82 (2020)
Abstract Objective Development of biomarkers for Charcot‐Marie‐Tooth (CMT) disease is critical for implementing effective clinical trials. The most common form of CMT, type 1A, is caused by a genomic duplication surrounding the PMP22 gene. A rece
Externí odkaz:
https://doaj.org/article/dc9e0a2aa18948ce9654a875eb019133
Autor:
Laura J Wagstaff, Jose A Gomez-Sanchez, Shaline V Fazal, Georg W Otto, Alastair M Kilpatrick, Kirolos Michael, Liam YN Wong, Ki H Ma, Mark Turmaine, John Svaren, Tessa Gordon, Peter Arthur-Farraj, Sergio Velasco-Aviles, Hugo Cabedo, Cristina Benito, Rhona Mirsky, Kristjan R Jessen
Publikováno v:
eLife, Vol 10 (2021)
After nerve injury, myelin and Remak Schwann cells reprogram to repair cells specialized for regeneration. Normally providing strong regenerative support, these cells fail in aging animals, and during chronic denervation that results from slow axon g
Externí odkaz:
https://doaj.org/article/71cf5cebbc4d40f8b6b3a29c0b196abc
Autor:
Ki H Ma, John Svaren
Publikováno v:
Neural Regeneration Research, Vol 11, Iss 12, Pp 1930-1931 (2016)
Externí odkaz:
https://doaj.org/article/1b23f881174c459b98d7e520b1ab0ef3
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e109691 (2014)
As next generation sequencing technologies are becoming more economical, large-scale ChIP-seq studies are enabling the investigation of the roles of transcription factor binding and epigenome on phenotypic variation. Studying such variation requires
Externí odkaz:
https://doaj.org/article/dcecdd29a7a644c7a07dfc1285217171
Autor:
Bing Yang, Jennifer Wagner, Nathan Damaschke, Tianyu Yao, Shelly M Wuerzberger-Davis, Moon-Hee Lee, John Svaren, Shigeki Miyamoto, David F Jarrard
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88052 (2014)
Genomic imprinting is the allele-specific expression of a gene based on parental origin. Loss of imprinting(LOI) of Insulin-like Growth Factor 2 (IGF2) during aging is important in tumorigenesis, yet the regulatory mechanisms driving this event are l
Externí odkaz:
https://doaj.org/article/779d296eedde458483ef15fd6b12345d
Autor:
Helena Bujalka, Matthias Koenning, Stacey Jackson, Victoria M Perreau, Bernard Pope, Curtis M Hay, Stanlislaw Mitew, Andrew F Hill, Q Richard Lu, Michael Wegner, Rajini Srinivasan, John Svaren, Melanie Willingham, Ben A Barres, Ben Emery
Publikováno v:
PLoS Biology, Vol 11, Iss 8, p e1001625 (2013)
The myelination of axons is a crucial step during vertebrate central nervous system (CNS) development, allowing for rapid and energy efficient saltatory conduction of nerve impulses. Accordingly, the differentiation of oligodendrocytes, the myelinati
Externí odkaz:
https://doaj.org/article/946c16919be64298bd55ab4d3e4a051d
Publikováno v:
Glia. 71:1466-1480
Autor:
Francesca A Veneri, Valeria Prada, Rosa Mastrangelo, Cinzia Ferri, Lucilla Nobbio, Mario Passalacqua, Maria Milanesi, Francesca Bianchi, Ubaldo Del Carro, Jean-Michel Vallat, Phu Duong, John Svaren, Angelo Schenone, Marina Grandis, Maurizio D’Antonio
Publikováno v:
Human Molecular Genetics. 31:4255-4274
Mutations in the Myelin Protein Zero gene (MPZ), encoding P0, the major structural glycoprotein of peripheral nerve myelin, are the cause of Charcot–Marie-Tooth (CMT) type 1B neuropathy, and most P0 mutations appear to act through gain-of-function
Autor:
David F. Jarrard, Richard Weindruch, John Svaren, Mark Berres, Rajini Srinivasan, Jonathan A. Ewald, Nima Almassi, Joshua A. Desotelle, Joseph R. Dobosy, Vivian X. Fu
Supplementary Figures 1-2 from Aging and Cancer-Related Loss of Insulin-like Growth Factor 2 Imprinting in the Mouse and Human Prostate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e523243b5790625bf479da8e9c2b4d
https://doi.org/10.1158/0008-5472.22377275.v1
https://doi.org/10.1158/0008-5472.22377275.v1