Zobrazeno 1 - 10
of 17
pro vyhledávání: '"John Shupe"'
Autor:
Adam I. Marcus, Melissa Gilbert-Ross, Gabriel Sica, Hans E. Grossniklaus, W. David Martin, W.G. Wiles, John Shupe, Jessica M. Konen, Allyson E. Koyen, Lauren S. Havel, Alessandra M. Richardson
Purpose: Vimentin is an epithelial-to-mesenchymal transition (EMT) biomarker and intermediate filament protein that functions during cell migration to maintain structure and motility. Despite the abundance of clinical data linking vimentin to poor pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a544233e5520d2329cb9ea2caad134f5
https://doi.org/10.1158/1078-0432.c.6526205
https://doi.org/10.1158/1078-0432.c.6526205
Autor:
Gabriel Sica, John Shupe, Walter Guy Wiles, Adam I. Marcus, Hans E. Grossniklaus, Melissa Gilbert-Ross, Jessica Konen, Allyson E. Koyen, Alessandra M. Richardson, Lauren S. Havel, W. David Martin
Publikováno v:
Clinical Cancer Research. 24:420-432
Purpose: Vimentin is an epithelial-to-mesenchymal transition (EMT) biomarker and intermediate filament protein that functions during cell migration to maintain structure and motility. Despite the abundance of clinical data linking vimentin to poor pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5524efb641b30146040fa626d27b352
https://doi.org/10.1158/1078-0432.ccr-17-1776
https://doi.org/10.1158/1078-0432.ccr-17-1776
Autor:
Melissa, Gilbert-Ross, Jessica, Konen, Junghui, Koo, John, Shupe, Brian S, Robinson, Walter Guy, Wiles, Chunzi, Huang, W David, Martin, Madhusmita, Behera, Geoffrey H, Smith, Charles E, Hill, Michael R, Rossi, Gabriel L, Sica, Manali, Rupji, Zhengjia, Chen, Jeanne, Kowalski, Andrea L, Kasinski, Suresh S, Ramalingam, Haian, Fu, Fadlo R, Khuri, Wei, Zhou, Adam I, Marcus
Publikováno v:
JCI insight. 2(5)
Loss of LKB1 activity is prevalent in KRAS mutant lung adenocarcinoma and promotes aggressive and treatment-resistant tumors. Previous studies have shown that LKB1 is a negative regulator of the focal adhesion kinase (FAK), but in vivo studies testin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bc9cc8a882861dbdb9d64adf5a857216
https://pubmed.ncbi.nlm.nih.gov/28289710
https://pubmed.ncbi.nlm.nih.gov/28289710
Autor:
Geoffrey H. Smith, Junghui Koo, Charles E. Hill, Melissa Gilbert-Ross, Michael R. Rossi, Andrea L. Kasinski, Wei Zhou, Zhengjia Chen, Manali Rupji, Gabriel Sica, W. David Martin, Madhusmita Behera, Fadlo R. Khuri, Walter Guy Wiles, Jeanne Kowalski, Jessica Konen, Haian Fu, Adam I. Marcus, Suresh S. Ramalingam, Brian S. Robinson, Chunzi Huang, John Shupe
Publikováno v:
JCI Insight. 2
Loss of LKB1 activity is prevalent in KRAS mutant lung adenocarcinoma and promotes aggressive and treatment-resistant tumors. Previous studies have shown that LKB1 is a negative regulator of the focal adhesion kinase (FAK), but in vivo studies testin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98cc2b15207081748796298a274e6de8
https://doi.org/10.1172/jci.insight.90487
https://doi.org/10.1172/jci.insight.90487
Autor:
John Shupe, Christopher Potter
Publikováno v:
JAWRA Journal of the American Water Resources Association. 50:153-162
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2496923b5568b0c0a603948c1a4e6c50
https://doi.org/10.1111/jawr.12124
https://doi.org/10.1111/jawr.12124
Publikováno v:
Journal of Biological Chemistry. 288:17663-17674
Liver kinase β1 (LKB1, also known as STK11) is a serine/threonine kinase that has multiple cellular functions including the regulation of cell polarity and motility. Murine proteomic studies show that LKB1 loss causes aberrant adhesion signaling; ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3beac26a5dee3a6943a10cbc9965214f
https://doi.org/10.1074/jbc.m112.444620
https://doi.org/10.1074/jbc.m112.444620
Autor:
Ganesh V. Raj, William H. Walker, Corey Toocheck, Chelsea M. Crum, Kyle E. Orwig, Preethi Ravindranathan, Terri Clister, Meena Sukhwani, Tae-Kyung Lee, Jung-Mo Ahn, John Shupe
Publikováno v:
Biology of Reproduction. 94
Testosterone acts though the androgen receptor in Sertoli cells to support germ cell development (spermatogenesis) and male fertility, but the molecular and cellular mechanisms by which testosterone acts are not well understood. Previously, we found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::200f9ff4090f811d52cb844d4a6d2c14
https://doi.org/10.1095/biolreprod.115.132068
https://doi.org/10.1095/biolreprod.115.132068
Publikováno v:
Journal of Water and Climate Change. 1:36-54
River discharge rates across all California's watershed have been modeled using the NASA version of the Carnegie-Ames-Stanford Approach (CASA) ecosystem model coupled with a surface hydrologic routing scheme previously called the Hydrological Routing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06c83b015794a153d96b64ebde75b3d3
https://doi.org/10.2166/wcc.2010.012
https://doi.org/10.2166/wcc.2010.012
Autor:
Corey, Toocheck, Terri, Clister, John, Shupe, Chelsea, Crum, Preethi, Ravindranathan, Tae-Kyung, Lee, Jung-Mo, Ahn, Ganesh V, Raj, Meena, Sukhwani, Kyle E, Orwig, William H, Walker
Publikováno v:
Biology of reproduction. 94(1)
Testosterone acts though the androgen receptor in Sertoli cells to support germ cell development (spermatogenesis) and male fertility, but the molecular and cellular mechanisms by which testosterone acts are not well understood. Previously, we found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fad6ff057adf96d81e3108ce76529915
https://pubmed.ncbi.nlm.nih.gov/26740590
https://pubmed.ncbi.nlm.nih.gov/26740590
Autor:
Lauren S. Havel, Allyson E. Koyen, Alessandra M. Salgueiro, Gabriel Sica, Melissa Gilbert-Ross, Adam I. Marcus, John Shupe, Hans E. Grossniklaus
Publikováno v:
Cancer Research. 76:C24-C24
Vimentin is an intermediate filament protein that has been used in the clinic as a biomarker for metastatic potential and poor patient prognosis across numerous solid tumor types; however, little is known about how vimentin might contribute to cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a26a50770822a48f52d696b76752d7a4
https://doi.org/10.1158/1538-7445.tme16-c24
https://doi.org/10.1158/1538-7445.tme16-c24