Zobrazeno 1 - 2
of 2
pro vyhledávání: '"John Sensintaffer"'
Autor:
Michael R. Savona, Melissa A. Fischer, Leah Hogdal, Agnieszka E. Gorska, John Sensintaffer, Edward T. Olejniczak, Stephen W. Fesik, Pia Arrate, Haley E. Ramsey, Taekyu Lee
Publikováno v:
Cancer Research. 77:4316-4316
Myeloid cell leukemia-1 (MCL-1) is a prosurvival BCL-2 family member protein commonly overexpressed in cancer, including hematologic malignancies. The successful use of BH3 mimetics against other anti-apoptotic proteins has validated the potential of
Autor:
Melinda Kozloski, Wilson Edwards, Judith Greengard, Duane Brumm, Douglas J. Jolly, Larisa Lillegren, John Sensintaffer, James E. McCormack, Linda Karavodin
Publikováno v:
Molecular Therapy. 3:516-525
We have studied parameters affecting in vivo expression of human growth hormone (hGH) in mice after intravenous administration of a retroviral vector encoding the protein as a model system for clotting factor VIII gene therapy. Such treatment results