Zobrazeno 1 - 10
of 11
pro vyhledávání: '"John Santoyo"'
Autor:
Andrea H. Venable, Lauren E. Lee, Kyle Feola, John Santoyo, Tatyana Broomfield, Sarah C. Huen
Publikováno v:
Am J Physiol Renal Physiol
Mitochondrial hydroxymethylglutaryl-CoA synthase 2 (HMGCS2) is the rate-limiting enzyme in ketogenesis. The liver expresses high levels of HMGCS2 constitutively as the main ketogenic organ. It has been suggested that the kidney could be ketogenic as
Autor:
Andrew Dang, Rey-Chen Pong, Rajni Sonavane, Ho Lin, Shihong Ma, Arnaldo A. Arbini, Shu-Fen Tseng, Elizabeth Hernandez, John Santoyo, Jer Tsong Hsieh, Ganesh V. Raj, Payal Kapur, Leah Gandee, U-Ging Lo, Loredana Moro, Diane Yang, Jun Huang, Chih Ho Lai, Dalin He, Chung Jung Lin
Publikováno v:
Cancer Research. 79:1098-1112
IFNγ, a potent cytokine known to modulate tumor immunity and tumoricidal effects, is highly elevated in patients with prostate cancer after radiation. In this study, we demonstrate that IFNγ can induce epithelial-to-mesenchymal transition (EMT) in
Autor:
Priscilla Anderton, Stephen Aplin Lyon, Zhao Zhang, Takuma Misawa, Meron Tadesse, Duanwu Zhang, Tao Yue, Miao Tang, Lindsay Scott, Jeffrey A. SoRelle, Hexin Shi, Jennifer Cardin, Sydney Cooper, Jiexia Quan, Jin Huk Choi, Nathan Stewart, Emre E. Turer, Chun Hui Bu, Sara Schneider, Xue Zhong, Dawson Medler, Katie Keller, Alexyss Johnson, Brandon Nguyen, Darui Xu, Braden Hayse, Bruce Beutler, Lei Sun, Jianhui Wang, Evan Nair-Gill, Edward Rodriguez, Aijie Liu, Sara Hildebrand, Qihua Sun, Andrew Wadley, Sara Mazal, Xiaohong Li, Gabrielle Coolbaugh, Ying Wang, Rochelle Simpson, Eva Marie Y. Moresco, John Santoyo, Baifang Qin, Roxana Farokhnia, Andrew Sakla, Amy Bronikowski, Hannah Coco
When applied to immunity, forward genetic studies use meiotic mapping to provide strong statistical evidence that a particular mutation is causative of a particular immune phenotype. Notwithstanding this, co-segregation of multiple mutations, occasio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4269fd5529c6dce400ad68cea677a9ea
https://doi.org/10.1101/2020.11.07.371914
https://doi.org/10.1101/2020.11.07.371914
Autor:
Yi-Qiang Cheng, Rey-Chen Pong, Elizabeth Hernandez, Shihong Ma, John Santoyo, Wei Chen, Dalin He, Bin Wang, Jun Huang, Xiangyang Liu, U-Ging Lo, Kaijie Wu, Jer Tsong Hsieh, Payal Kapur
Publikováno v:
International Journal of Cancer. 141:2121-2130
The presence of androgen receptor variant 7 (AR-V7) variants becomes a significant hallmark of castration-resistant prostate cancer (CRPC) relapsed from hormonal therapy and is associated with poor survival of CRPC patients because of lacking a ligan
Autor:
Dalin He, Chih Ho Lai, Ho Lin, Chun-Jung Lin, Jiancheng Zhou, Jer Tsong Hsieh, John Santoyo, Shan Xu, Eun-Jin Yun, Elizabeth Hernandez
Publikováno v:
Oncotarget
// Eun-Jin Yun 1, * , Jiancheng Zhou 1, 2 , Chun-Jung Lin 1 , Shan Xu 1, 3 , John Santoyo 1 , Elizabeth Hernandez 1 , Chih-Ho Lai 4 , Ho Lin 5 , Dalin He 3 and Jer-Tsong Hsieh 1, 6, * 1 Department of Urology, University of Texas Southwestern Medical
Autor:
Eun-Jin Yun, Dalin He, John Santoyo, Ye Ding, Haiying Chen, Kaijie Wu, Ho Lin, Jiancheng Zhou, Jer Tsong Hsieh, Chunyong Ding, Bin Wang, Arthur I. Sagalowsky, Wei Chen, Elizabeth Hernandez, Jun Huang, Jia Zhou
Publikováno v:
Oncotarget
// Wei Chen 1, 2, * , Jiancheng Zhou 3, * , Kaijie Wu 1 , Jun Huang 1 , Ye Ding 4 , Eun-Jin Yun 2 , Bin Wang 1, 2 , Chunyong Ding 4 , Elizabeth Hernandez 2 , John Santoyo 2 , Haiying Chen 4 , Ho Lin 5 , Arthur Sagalowsky 2 , Dalin He 1 , Jia Zhou 4 ,
IFN-γ induces epithelial-to-mesenchymal transition of cancer cells via an unique microRNA processing
Autor:
Ho Lin, Diane Yang, Andrew Dang, Loredana Moro, Jer Tsong Hsieh, Payal Kapur, Leah Gandee, Rajni Sonavane, Chih Ho Lai, Elizabeth Hernandez, Ganesh V. Raj, Shu Fen Tseng, John Santoyo, U. Ging Lo, Rey Chen Pong, Shihong Ma, Chung Jung Lin, Dalin He, Jun Huang, Arnaldo A. Arbini
Interferon-γ (IFNγ) is a potent cytokine in modulating tumor immunity and tumoricidal effects. We demonstrate a new function of IFNγ in inducing epithelial-to-mesenchymal transition (EMT) in normal and cancer cells from different cell types. IFNγ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036774fffc93bb15f4a020df838d9b24
https://doi.org/10.1101/355263
https://doi.org/10.1101/355263
Autor:
Haiying Chen, Jer Tsong Hsieh, Ye Ding, Rey Chen Pong, Kaijie Wu, Eun-Jin Yun, Wei Chen, Jia Zhou, Bin Wang, Jiancheng Zhou, Elizabeth Hernandez, John Santoyo, Dalin He, Chunyong Ding
Publikováno v:
Cell Death & Disease
The current agents used for renal cell carcinoma (RCC) only exhibit the moderate response rate among patients. Development of drug resistance eventually fuels the need of either more potent drugs or new drugs to target the resistant pathways. Oridoni
Autor:
Eun-Jin Yun, John Santoyo, Jiancheng Zhou, Chun-Jung Lin, Elizabeth Hernandez, Jer Tsong Hsieh
Publikováno v:
Cancer Research. 75:3078-3078
Chemotherapy is the standard care for metastatic disease, in renal cell carcinoma (RCC), the outcome of chemotherapy only prolongs short survival of patients. The reason for the resistance of RCC to chemotherapy is not fully understood, although it h
Autor:
David J. Maloney, Elisabeth D. Martinez, Anton Simeonov, Ganesha Rai, John Santoyo, Lingling Duan, Carlos M. Roggero, Jer Tsong Hsieh, Ajit Jadhav, Qing Jun Zhang, Shihong Ma, Guanghua Xiao, Ganesh V. Raj, Zhi Ping Liu, Qun Wei, Yunyun Zhou, Josep Rizo
Publikováno v:
Chemistry & Biology. (9):1185-1196
Summary Histone lysine demethylase KDM4/JMJD2s are overexpressed in many human tumors including prostate cancer (PCa). KDM4s are co-activators of androgen receptor (AR) and are thus potential therapeutic targets. Yet to date few KDM4 inhibitors that