Zobrazeno 1 - 10
of 129
pro vyhledávání: '"John Samuelson"'
Publikováno v:
mSphere, Vol 9, Iss 9 (2024)
ABSTRACT The cyst wall of the eye pathogen Acanthamoeba castellanii contains cellulose and has ectocyst and endocyst layers connected by conical ostioles. Cyst walls contain families of lectins that localize to the ectocyst layer (Jonah) or the endoc
Externí odkaz:
https://doaj.org/article/ebc3c28686a5495188aafddca0af4041
Autor:
Pamela Magistrado-Coxen, Yousuf Aqeel, Angelo Lopez, John R Haserick, Breeanna R Urbanowicz, Catherine E Costello, John Samuelson
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 5, p e0007352 (2019)
BackgroundAcanthamoeba castellanii, which causes keratitis and blindness in under-resourced countries, is an emerging pathogen worldwide, because of its association with contact lens use. The wall makes cysts resistant to sterilizing reagents in lens
Externí odkaz:
https://doaj.org/article/614497fdf9cd46d5ac998e60b7f4b006
Autor:
Rashmi Dubey, Brooke Harrison, Sriveny Dangoudoubiyam, Giulia Bandini, Katherine Cheng, Aziz Kosber, Carolina Agop-Nersesian, Daniel K. Howe, John Samuelson, David J. P. Ferguson, Marc-Jan Gubbels
Publikováno v:
mSphere, Vol 2, Iss 5 (2017)
ABSTRACT The inner membrane complex (IMC) of apicomplexan parasites contains a network of intermediate filament-like proteins. The 14 alveolin domain-containing IMC proteins in Toxoplasma gondii fall into different groups defined by their distinct sp
Externí odkaz:
https://doaj.org/article/42927399fafb4a71bb9dae7a12a49fc4
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 2, p e0005382 (2017)
BACKGROUND:Blindness is caused by eye pathogens that include a free-living protist (Acanthamoeba castellanii, A. byersi, and/or other Acanthamoeba spp.), a fungus (Fusarium solani), and a bacterium (Chlamydia trachomatis). Hand-eye contact is likely
Externí odkaz:
https://doaj.org/article/83f6160939ae468c81d5c74fdbcd51f5
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182395 (2017)
Cryptosporidium parvum (studied here) and Cryptosporidium hominis are important causes of diarrhea in infants and immunosuppressed persons. C. parvum vaccine candidates, which are on the surface of sporozoites, include glycoproteins with Ser- and Thr
Externí odkaz:
https://doaj.org/article/5ef6d8e65aac4ac7bc774257795dd423
Autor:
Aparajita Chatterjee, Daniel M Ratner, Christopher M Ryan, Patricia J Johnson, Barry R O'Keefe, W Evan Secor, Deborah J Anderson, Phillips W Robbins, John Samuelson
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135340 (2015)
Trichomonas vaginalis causes vaginitis and increases the risk of HIV transmission by heterosexual sex, while Tritrichomonas foetus causes premature abortion in cattle. Our goals were to determine the effects, if any, of anti-retroviral lectins, which
Externí odkaz:
https://doaj.org/article/8028774591a340afa9af98104adec135
Autor:
G. Guy Bushkin, Edwin Motari, Andrea Carpentieri, Jitender P. Dubey, Catherine E. Costello, Phillips W. Robbins, John Samuelson
Publikováno v:
mBio, Vol 4, Iss 5 (2013)
ABSTRACT Coccidia are protozoan parasites that cause significant human disease and are of major agricultural importance. Cryptosporidium spp. cause diarrhea in humans and animals, while Toxoplasma causes disseminated infections in fetuses and untreat
Externí odkaz:
https://doaj.org/article/532d26501f0245268bfea8484ef40206
Autor:
G. Guy Bushkin, Edwin Motari, Paula Magnelli, Marc-Jan Gubbels, Jitender P. Dubey, Katarzyna B. Miska, Esther Bullitt, Catherine E. Costello, Phillips W. Robbins, John Samuelson
Publikováno v:
mBio, Vol 3, Iss 5 (2012)
ABSTRACT The walls of infectious pathogens, which are essential for transmission, pathogenesis, and diagnosis, contain sugar polymers that are defining structural features, e.g., β-1,3-glucan and chitin in fungi, chitin in Entamoeba cysts, β-1,3-Ga
Externí odkaz:
https://doaj.org/article/de73b5bc33504372be351280c253957a
Autor:
Aparajita Chatterjee, Andrea Carpentieri, Daniel M Ratner, Esther Bullitt, Catherine E Costello, Phillips W Robbins, John Samuelson
Publikováno v:
PLoS Pathogens, Vol 6, Iss 8, p e1001059 (2010)
The infectious and diagnostic stage of Giardia lamblia (also known as G. intestinalis or G. duodenalis) is the cyst. The Giardia cyst wall contains fibrils of a unique beta-1,3-linked N-acetylgalactosamine (GalNAc) homopolymer and at least three cyst
Externí odkaz:
https://doaj.org/article/66fab067d50b4866ba818ca1e2e623ca
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 8, p e782 (2010)
Trichomonas vaginalis has an unusually large genome (approximately 160 Mb) encoding approximately 60,000 proteins. With the goal of beginning to understand why some Trichomonas genes are present in so many copies, we characterized here a family of ap
Externí odkaz:
https://doaj.org/article/7c78594975fd4b13a7b98f5037567795