Zobrazeno 1 - 10
of 107
pro vyhledávání: '"John S. Sussenbach"'
Autor:
Manfred Reinecke, Elly Holthuizen, Olga Gritsenko, Antje Caelers, John S. Sussenbach, Alex Palamarchuk, V. M. Kavsan
Publikováno v:
Gene, 295(2), 223-30. Elsevier
Palamarchuk, A, Gritsenko, O V, Holthuizen, E, Sussenbach, J, Caelers, A, Reinecke, M & Kavsan, V 2002, ' Complete nucleotide sequence of the chum salmon insulin-like growth factor II gene ', Gene, vol. 295, no. 2, pp. 223-30 . https://doi.org/10.1016/S0378-1119(02)00731-X
Palamarchuk, A, Gritsenko, O V, Holthuizen, E, Sussenbach, J, Caelers, A, Reinecke, M & Kavsan, V 2002, ' Complete nucleotide sequence of the chum salmon insulin-like growth factor II gene ', Gene, vol. 295, no. 2, pp. 223-30 . https://doi.org/10.1016/S0378-1119(02)00731-X
Insulin-like growth factor II (IGF-II) is thought to play an important role in development and growth of vertebrates. In contrast to mammals, the IGF-II gene is expressed at a high level from the early stages of embryonic development until the adult
Publikováno v:
Molecular and Cellular Endocrinology. 172:57-67
The chum salmon insulin-like growth factor II (IGF-II) gene is highly expressed in liver tissue. In this study we demonstrate that two transcription factors, Sp1 and C/EBPbeta, are involved in the enhanced expression of the salmon IGF-II gene. The pr
Publikováno v:
Journal of Molecular Biology. 300:449-467
The insulin-like growth factor II mRNAs are targets for site-specific endonucleolytic cleavage in the 3′-UTR, which results in a very stable 3′ cleavage product of 1.8 kb, consisting of 3′-UTR sequences and a poly(A) tail. The 5′ cleavage pro
Publikováno v:
Biochemical Journal. 338:799-806
The human insulin-like growth factor II (IGF-II) gene contains four promoters that are differentially active during cell growth and development. Promoter 3 (P3) is the most active promoter in fetal and non-hepatic adult tissues. In addition to its ex
Publikováno v:
FEBS Letters. 444:155-159
Salmon insulin-like growth factor-I (sIGF-I) expression is, as in mammals, induced by growth hormone (GH). To elucidate the mechanism by which GH stimulates the transcription of the IGF-I gene, we transiently transfected Hep3B cells expressing the ra
Publikováno v:
RNA. 4:1623-1635
Insulin-like growth factor-II (IGF-II) mRNAs are subject to site-specific endonucleolytic cleavage in the 3' untranslated region (UTR), rendering an unstable 5' cleavage product containing the coding region and a very stable 3' cleavage product of 1.
Autor:
Hetty A.A.M. van Teeffelen, Frederik M. A. van Schaik, Brigitte Dufourny, Bart van der Burg, P.H. Steenbergh, Jacqueline Alblas, John S. Sussenbach
Publikováno v:
Journal of Biological Chemistry. 272:31163-31171
Addition of insulin-like growth factor I (IGF-I) to quiescent breast tumor-derived MCF-7 cells causes stimulation of cyclin D1 synthesis, hyperphosphorylation of the retinoblastoma protein pRb, DNA synthesis, and cell division. All of these effects a
Publikováno v:
Biochemical Journal. 327:689-697
Transcription of the human insulin-like growth factor II (IGF-II) gene is under the control of four promoters (P1-P4) that are differentially active during growth and development. Promoter 3 (P3) is the most active promoter during fetal development a
Autor:
John S. Sussenbach, Werner E.G. Müller, Alexey Y. Palamarchuk, Vadim M. Kavsan, P. Elly Holthuizen
Publikováno v:
FEBS Letters. 416:344-348
IGF-II plays an important role in growth and development of vertebrates. In the present study, the characterization of the first fish IGF-II gene, chum salmon IGF-II, is described. The sIGF-II gene consists of four exons, spanning a region of 9 kbp,
Publikováno v:
Molecular Endocrinology. 11:237-250
The human gene encoding insulin-like growth factor II contains four promoters (P1–P4) that are differentially activated in various tissues during development. Expression of insulin-like growth factor II in adult liver tissue is directed by P1, whic