Zobrazeno 1 - 10
of 12
pro vyhledávání: '"John S. Salstrom"'
Publikováno v:
Virology. 98:411-423
Transcriptional studies of gene expression in coliphage λ reveal a complex set of interactions involving host RNA polymerase and the positive and negative regulatory functions of the phage genes N and cro, respectively. The N product, which is known
Publikováno v:
Gene. 5:305-327
A short interval of homology between imm λ, imm 434 and imm 21 DNAs was identified near the leftward promoter-operator region. This homology, denoted Hs, was revealed by electron microscopic examination of λ imm λ/λ imm 21 and λ imm 434/λ imm 2
Publikováno v:
Science. 218:381-384
The protein coding region of the herpes simplex virus type-1 glycoprotein D (gD) gene was mapped, and the nucleotide sequence was determined. The predicted amino acid sequence of the gD polypeptide was found to contain a number of features in common
Publikováno v:
Molecular and General Genetics MGG. 168:211-230
Lambda mutants capable of N-independent red-gam gene expression were isolated by selecting Fec+ plaque-forming derivatives of lambda N+ nutL- (Fec-) strains. In addition to true nutL+ reversions, three classes of second-site mutations were identified
Autor:
Waclaw Szybalski, John S. Salstrom
Publikováno v:
Journal of Molecular Biology. 124:195-221
A special procedure was developed to isolate a new class of plaque-forming (Spi − ) mutants of phage λ that are unable to express the leftward N -dependent red and gam gene functions by reason of cis -dominant defects located between the p L promo
Autor:
John S. Salstrom, David Pratt
Publikováno v:
Journal of Molecular Biology. 61:489-501
The phage M13 gene 5 protein is shown to play a negative role in the production of viral single-stranded DNA. This protein blocks the function of a DNA polymerase which is capable of converting intracellular single strands to double-stranded replicat
Autor:
Waclaw Szybalski, John S. Salstrom
Publikováno v:
Virology. 88(2)
A transcriptional mapping technique was employed to determine the locations of leftward transcription termination sites within the pL-att region of bacteriophage λ. Lysogens in which phage or host mutations blocked N-mediated antitermination were us
Publikováno v:
Gene. 10(1)
An in vitro assay has been developed for the antiterminating activity of the N gene product (pN) of bacteriophage lambda, based on the N-dependent stimulation of trp mRNA synthesis from the DNA templates of lambda trp transducing phages. Using this a
Publikováno v:
Nature. 302(5903)
Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) cause both persistent and latent infections, including recurrent cutaneous disease, lethal neonatal disease, central nervous system disease and other clinical syndromes. Modified live vaccines or
Publikováno v:
The Journal of investigative dermatology. 83
We have used elements of the E. coli lactose ( lac ) Operon to produce a collection of herpes simplex virus types 1 and 2 glycoprotein D (gD-1 and gD-2) antigens. Our approach employed recombinant DNA techniques to construct plasmids with various seg