Zobrazeno 1 - 10
of 23
pro vyhledávání: '"John S. McLean"'
Autor:
John S. McLean
Publikováno v:
New Mexico Geological Society, 2022 Annual Spring Meeting, Proceedings Volume, Theme: "Karst in New Mexico in recognition of 2022 being the International Year of Caves and Karst".
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b28fdcfefe7f752cfe1c3b39bddd699
https://doi.org/10.56577/sm-2022.2815
https://doi.org/10.56577/sm-2022.2815
Autor:
Christian P. Sommerhoff, John S. McLean, Lynette Dunning, EB Kelso, Morley D. Hollenberg, Robin Plevin, John C. Lockhart, Todd Hembrough, William R. Ferrell
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 316:1017-1024
Biological therapies such as tumor necrosis factor-alpha inhibitors have advanced the treatment of rheumatoid arthritis, but one-third of patients do not respond to such therapy. Furthermore, these inhibitors are now usually administered in combinati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ede382d7da566ee10a1e6b9c472926c
https://doi.org/10.1124/jpet.105.093807
https://doi.org/10.1124/jpet.105.093807
Publikováno v:
The Journal of Physiology. 539:579-587
The role of different isoforms of cyclo-oxygenase (COX) in mediating the acute (0-6 h) and late (24 h) phases of inflammation was investigated in the rat knee joint following intra-articular injection of carrageenan. The hyperaemic response was asses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f5449ac012998c3d8fb7381ab63165
https://doi.org/10.1113/jphysiol.2001.013473
https://doi.org/10.1113/jphysiol.2001.013473
Publikováno v:
Electroanalysis. 12:490-494
A sensitive electrochemical assay method is described for secreted placental alkaline phosphatase (SPAP). The enzyme activity is measured using 2-naphthyl phosphate as the electrochemical substrate. The product of the reaction, 2-naphthol, is detecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c50c11ae05c9105946b5a70f13fa89ce
https://doi.org/10.1002/(sici)1521-4109(200005)12:7<490::aid-elan490>3.0.co
https://doi.org/10.1002/(sici)1521-4109(200005)12:7<490::aid-elan490>3.0.co
Publikováno v:
Cytotechnology. 32:209-218
The aim of this study was to improve the survival ofNIH3T3 cells in low serum or serum-free media by theendogenous expression of recombinant bFGF (basicfibroblast growth factor) and/or IGF (insulin-likegrowth factor) -I and II. Expression was detecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3e81e6d06d9960b8eb757bad5c7c84b
https://doi.org/10.1023/a:1008151302358
https://doi.org/10.1023/a:1008151302358
Publikováno v:
Journal of Cardiovascular Pharmacology. 26:978-982
We have developed a cell based assay for the functional screening of chemical libraries for novel chemical entities active at the human endothelin A (ET A ) receptor. The assay is relatively inexpensive, suitable for dealing with large numbers of sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abba36aa506aaf81e75137f32a5d2993
https://doi.org/10.1097/00005344-199512000-00019
https://doi.org/10.1097/00005344-199512000-00019
Autor:
John S. McLean, Robert J. Byrick
Publikováno v:
Canadian Journal of Anaesthesia. 40:585-590
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e529a16c002588d6950a05a0d41819f8
https://doi.org/10.1007/bf03009692
https://doi.org/10.1007/bf03009692
Autor:
John S. McLean
Publikováno v:
Trends in Biotechnology. 11:232-238
The use of cultured mammalian cells for assessing potential new drugs and for basic biological research is increasing, since it facilitates the large-scale screening of candidate drugs and reduces the need for animal experimentation. In this review,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee2beeb1669c90cf92a0550b72957cf
https://doi.org/10.1016/0167-7799(93)90134-u
https://doi.org/10.1016/0167-7799(93)90134-u
Publikováno v:
Annals of the rheumatic diseases. 63(12)
Background: Nitrergic and prostanoid pathways have both been implicated in inflammatory processes. Objective: To investigate their respective contributions in a rat model of chronic arthritis. Methods: Male Wistar rats (n = 4–6/group) received eith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5418b4c786ae6062d9dce2a10bb3413b
https://pubmed.ncbi.nlm.nih.gov/15547079
https://pubmed.ncbi.nlm.nih.gov/15547079
