Zobrazeno 1 - 10
of 27
pro vyhledávání: '"John S. Janiszewski"'
Autor:
Stephen W. C. Walker, Ahdia Anwar, Jarrod M. Psutka, Jeff Crouse, Chang Liu, J. C. Yves Le Blanc, Justin Montgomery, Gilles H. Goetz, John S. Janiszewski, J. Larry Campbell, W. Scott Hopkins
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
The fast and accurate determination of molecular properties is particularly crucial in drug discovery. Here, the authors employ supervised machine learning to treat differential mobility spectrometry – mass spectrometry data for ten classes of drug
Externí odkaz:
https://doaj.org/article/e5545143641641f8afbe1987126bcf2f
Autor:
Chang Liu, J. C. Yves Le Blanc, Bradley B. Schneider, Jefry Shields, James J. Federico, Hui Zhang, Justin G. Stroh, Gregory W. Kauffman, Daniel W. Kung, Christian Ieritano, Evan Shepherdson, Mitch Verbuyst, Luke Melo, Moaraj Hasan, Dalia Naser, John S. Janiszewski, W. Scott Hopkins, J. Larry Campbell
Publikováno v:
ACS Central Science, Vol 3, Iss 2, Pp 101-109 (2017)
Externí odkaz:
https://doaj.org/article/cbf100c06b8f471a84cb2b68b644c164
Autor:
Chang Liu, J. C. Yves Le Blanc, Bradley B. Schneider, Jefry Shields, James J. Federico, Hui Zhang, Justin G. Stroh, Gregory W. Kauffman, Daniel W. Kung, Michael Shapiro, Christian Ieritano, Evan Shepherdson, Mitch Verbuyst, Luke Melo, Moaraj Hasan, Dalia Naser, John S. Janiszewski, W. Scott Hopkins, J. Larry Campbell
Publikováno v:
ACS Central Science, Vol 3, Iss 4, Pp 359-359 (2017)
Externí odkaz:
https://doaj.org/article/172d0a036ebf48b98a84a8d373d119ee
Autor:
Quinlin M. Hanson, Nate Hoxie, Min Shen, Hui Guo, Ig-Jun Cho, Ipsita Chakraborty, Brooklyn M. Aragon, Ganesha Rai, Samarjit Patnaik, John S. Janiszewski, Matthew D. Hall
Publikováno v:
ACS Chemical Biology. 18:969-981
Autor:
W. Scott Hopkins, Jarrod Psutka, Justin I. Montgomery, Chang Liu, Ahdia Anwar, J. C. Yves Le Blanc, Jeff Crouse, John S. Janiszewski, Gilles H. Goetz, Stephen W. C. Walker, J. Larry Campbell
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Nature Communications
Nature Communications
The fast and accurate determination of molecular properties is highly desirable for many facets of chemical research, particularly in drug discovery where pre-clinical assays play an important role in paring down large sets of drug candidates. Here,
Autor:
Brian R. Holder, Jianhua Liu, Mary Piotrowski, Julie Keefer, Matt D. Troutman, John S. Janiszewski, Hui Zhang, Brendon Kapinos
Publikováno v:
Bioanalysis. 9:1643-1654
Autor:
W. Scott Hopkins, Evan Shepherdson, Mitch Verbuyst, Chang Liu, John S. Janiszewski, Daniel W. Kung, Justin G. Stroh, James Federico, Christian Ieritano, Hui Zhang, Jefry E. Shields, Luke Melo, Bradley B. Schneider, J. C. Yves Le Blanc, J. Larry Campbell, Moaraj Hasan, Dalia Naser, Gregory W. Kauffman
Publikováno v:
ACS Central Science
ACS Central Science, Vol 3, Iss 2, Pp 101-109 (2017)
ACS Central Science, Vol 3, Iss 2, Pp 101-109 (2017)
The microsolvated state of a molecule, represented by its interactions with only a small number of solvent molecules, can play a key role in determining the observable bulk properties of the molecule. This is especially true in cases where strong loc
Autor:
Abhishek Jha, Darren Dumlao, Hozefa S. Bandukwala, Jennifer Alley, Tiago C. Alves, Mary Piotrowski, Samantha Hiemer, John S. Janiszewski, Shefali Lathwal, Shashank Jatav, Richard G. Kibbey, Jason Jussif
The targeting of metabolic pathways is emerging as an exciting new approach for modulating immune cell function and polarization states. In this study, carbon tracing and systems biology approaches integrating metabolomic and transcriptomic profiling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c5b2ae8f603d177d966419e6c2f97e4
https://doi.org/10.1101/635789
https://doi.org/10.1101/635789
Autor:
Nick Levitt, John S. Janiszewski
Publikováno v:
Eliminating Bottlenecks for Efficient Bioanalysis: Practices and Applications in Drug Discovery and Development. :34-50
Autor:
Yuya Maruyama, Sarah E. Johnston, Emma Armstrong, Csilla C. Jorgensen, Rubben Torella, Parul Choudhary, Caroline L. Benn, R. Ian Storer, Maria Barthmes, John S. Janiszewski, Sarah Elizabeth Skerratt, Mary Piotrowski
Publikováno v:
Frontiers in Molecular Neuroscience
Cholinergic hypofunction is associated with decreased attention and cognitive deficits in the central nervous system in addition to compromised motor function. Consequently, stimulation of cholinergic neurotransmission is a rational therapeutic appro