Výsledky vyhledávání - "John S. Hanekamp"

Evidence for a Gene Controlling the Induction of Transplantation Tolerance

Autor: Chisako Kamano, David H. Sachs, Robert A. Cina, Patricia Lee, Kazuhiko Yamada, John S. Hanekamp, Parsia A. Vagefi, Vincenzo Villani, Scott Arn, P. E. O'Malley

Publikováno v: American Journal of Transplantation. 14:952-959

Class I mismatched kidney transplantation in Massachusetts General Hospital MHC-defined miniature swine has been studied extensively as a model for induction of systemic allograft tolerance. In a large series of juvenile swine, long-term graft accept

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7fbcbee65326163b0882f5ea91ce822
https://doi.org/10.1111/ajt.12646

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Role of bone marrow maturity, insulin-like growth factor 1 receptor and forkhead box protein N1 in thymic involution and rejuvenation

Autor: Kazuhiko Yamada, John S. Hanekamp, Rei Yamada, I.M. Hanekamp, S. Moran, David H. Sachs, Masayuki Tasaki, Akihiro Kawai, Vincenzo Villani, M. Sekijima, Akira Shimizu, Taylor Cormack

Thymic involution is associated with age-related changes of the immune system. Utilizing our innovative technique of transplantation of a thymus as an isolated vascularized graft in MHC-inbred miniature swine, we have previously demonstrated that age

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a7e240e7d112736508a95071041870e
https://europepmc.org/articles/PMC5097038/

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Myelogenous leukemia in adult inbred MHC-defined miniature swine: A model for human myeloid leukemias

Publikováno v: Veterinary Immunology and Immunopathology. 135:243-256

This manuscript reports on five cases of spontaneous myelogenous leukemia, similar to human disease, occurring within highly inbred, histocompatible sublines of Massachusetts General Hospital (MGH) MHC-defined miniature swine. In cases where a neopla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22378387513a499755893a9dfa1c1c8
https://doi.org/10.1016/j.vetimm.2009.12.005

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Cytoplasmic Inheritance of Transplantation Antigens in Animals Produced by Nuclear Transfer

Autor: David H. Sachs, Aseda Tena, Scott Arn, Kazuhiko Yamada, John S. Hanekamp, Masayoshi Okumi

Publikováno v: Transplantation. 88:30-37

Background—Nuclear transfer has been utilized as a means of selectively modifying the mammalian genome. One possible consequence of this technology is that the oocytes used in nuclear transfer may provide additional antigens via cytoplasmic inherit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8f482355cff03386c94ca962000b32
https://doi.org/10.1097/tp.0b013e3181a9ed5b

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Selective Retrosigmoid Vestibular Neurectomy without Internal Auditory Canal Drill-out: An Anatomic Study

Autor: N. Scott Litofsky, Cliff A. Megerian, Matthew J Cosenza, John S Hanekamp

Publikováno v: Otology & Neurotology. 23:218-223

Objective It is well established that selective vestibular nerve section by means of the retrosigmoid or posterior fossa approach can be accomplished with or without drill-out of the internal auditory canal (IAC) by virtue of the presence or absence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5f9919903f27e7ff092db0628272300
https://doi.org/10.1097/00129492-200203000-00019

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Mitochondrial mutational spectra in human cells and tissues

Autor: Konstantin Khrapko, John S. Hanekamp, Hilary A. Coller, William G. Thilly, Paulo C. André, Xiao Cheng Li

Publikováno v: Proceedings of the National Academy of Sciences. 94:13798-13803

We have found that human organs such as colon, lung, and muscle, as well as their derived tumors, share nearly all mitochondrial hotspot point mutations. Seventeen hotspots, primarily G → A and A → G transitions, have been identified in the mitoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6926fa9a5f846bf46d58f882ccefe7fd
https://doi.org/10.1073/pnas.94.25.13798

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Approaches to avoid immune responses induced by repeated subcutaneous injections of allogeneic umbilical cord tissue-derived cells

Autor: Alexander G.S. Teague, Bram V. Lutton, Stuart L. Houser, Kelly K. Ferguson, Nina Chi, Christene A. Huang, Stephanie N. Goldman, Patricia S. Cho, Sicco H. Popma, David H. Sachs, Beow Y. Yeap, Erica L. Hirsh, John S. Hanekamp, Darin J. Messina

Publikováno v: Transplantation. 90(5)

Umbilical cord tissue-derived cells (UTC) were targeted as a source of multipotent progenitor cells due to the immune-privileged nature of the maternal-fetal interface (1). UTC have been believed to have a low immunogenic profile because they lack ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00816464ff8bc851e0b5c2b030ccad0
https://pubmed.ncbi.nlm.nih.gov/21451445

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Identification of point mutations in mixtures by capillary electrophoresis hybridization

Autor: William G. Thilly, John S. Hanekamp, Konstantin Khrapko, Hilary A. Coller

Publikováno v: Nucleic Acids Research. 26:5738-5740

We have developed a rapid method for unambiguous identification and mutant fraction determination of individual mutants in mixtures of DNA sequence variants each differing by one or a few nucleotides. This method has applications to such diverse area

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403bd00874d52141d1ba037d6b371b45
https://doi.org/10.1093/nar/26.24.5738

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