Coordinated regulation of acid resistance in Escherichia coli

Autor: Salwa Masud, Tyler Wagner, Junyu Lei, Anna Lyubetskaya, Brandon G. Wong, Chen Guo, Anna K. Hawes, John S. Greifenberger, Cong Ba, Lin Jin, Dongjian Hu, Dana Braff, David Li, Winnie S. Wong, Meghan Thommes, Alicia J. Zollinger, James E. Galagan, Christopher P. Mancuso, Daniel I. Cheng, Arion I. Stettner, Jessica E. Kim, Ning Mao, Alfred K. Ramirez, Stephen Alexander, Seth Bensussen, Hannah M. Peterson, Hang Su, Susie S. Cha, Benjamin H. Weinberg, Meng Sun, Jing Mi, Hao Li, Jang Hwan Cho, Nae Gyune Rim, Wilson W. Wong, Nitinun Varongchayakul, Anastasia I. Yaroslavsky, John W. Foster, Qian Li, Tao Tu, James Chuang, Jared C. Saffie, Joanna G. Chiu, Kenny F. Chou, Brent Honda, Natasha Broude, Daniel J. Grasso, Divya V. Israni, Daniel S. Reynolds, Rouhui Yang, Saloni R. Jain, Daniel Gastler, Christine Yoon, Yanyu Zhao, Patricia Aquino, Cari L. Meisel, Sahadaven Raman, Wendell R. Su, Anne M. Stringer, Marianna K. Sayeg, Minhee Park, David B. Bernstein, Yaqing Su, Iriny Ekladious, Krutika Hosur, Christine S. Nykyforchyn, Julia Wang, Suma Jaini, Joseph T. Wade

Publikováno v: BMC Systems Biology

Background Restriction-modification (R-M) systems are rudimentary bacterial immune systems. The main components include restriction enzyme (R), which cuts specific unmethylated DNA sequences, and the methyltransferase (M), which protects the same DNA

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