Zobrazeno 1 - 10
of 67
pro vyhledávání: '"John S. Clemmer"'
Publikováno v:
Frontiers in Systems Biology, Vol 4 (2024)
Chronic kidney disease (CKD) is associated with the progressive loss of functional nephrons and hypertension (HTN). Clinical studies demonstrate calcium channel blocker (CCB) therapy mitigates the decline in renal function in humans with essential HT
Externí odkaz:
https://doaj.org/article/f93718f693274e6bb6fe83d45ad319c0
Publikováno v:
ESC Heart Failure, Vol 10, Iss 3, Pp 2010-2018 (2023)
Abstract Aims Heart failure (HF) is one of the leading causes of cardiovascular morbidity and mortality. HF with preserved ejection fraction (HFpEF), or diastolic failure, accounts for half of all HF cases and differs from HF with reduced ejection fr
Externí odkaz:
https://doaj.org/article/e036d12b9026480b8a1d82d5b5d9ae43
Publikováno v:
Physiological Reports, Vol 11, Iss 21, Pp n/a-n/a (2023)
Abstract Sodium‐glucose cotransporter (SGLT)‐2 inhibitors have recently been approved for chronic kidney disease (CKD) based on their ability to lower proteinuria and slow CKD progression independent of diabetes status. In diabetic renal disease,
Externí odkaz:
https://doaj.org/article/78a60760b2b24f7a871f13b1b3dad875
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/e6a05ee5e2e048549211a36f4c251132
Publikováno v:
Biology of Sex Differences, Vol 10, Iss 1, Pp 1-7 (2019)
Abstract Background African Americans (AA) develop hypertension (HTN) at an earlier age, have a greater frequency and severity of HTN, and greater prevalence of uncontrolled HTN as compared to the white population. Mineralocorticoid antagonists have
Externí odkaz:
https://doaj.org/article/a60463a2ec8e4f59936bf012d1584d1a
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2021)
Externí odkaz:
https://doaj.org/article/1f3cd9d5660f41e9951ed27ea0ba9ac4
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
Clinical trials evaluating the efficacy of chronic electrical stimulation of the carotid baroreflex for the treatment of hypertension (HTN) are ongoing. However, the mechanisms by which this device lowers blood pressure (BP) are unclear, and it is un
Externí odkaz:
https://doaj.org/article/857433f776b44e92a9d7df63a816521f
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Objective: As compared to whites, the black population develops hypertension (HTN) at an earlier age, has a greater frequency and severity of HTN, and has poorer control of blood pressure (BP). Traditional practices and treatment efforts have had min
Externí odkaz:
https://doaj.org/article/27f67a160c6b4115b5e0ca1ca4f3266f
Publikováno v:
Clinical Science. 137:769-772
Despite the overwhelming evidence that the kidney is the principal regulator of chronic blood pressure though the ability to sense pressure and adjust blood volume accordingly, recent clinical and preclinical evidence suggests that skin clearance of
Autor:
John S. Clemmer, W. Andrew Pruett
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 323:H597-H607
Heart failure (HF) is a leading cause of death and is increasing in prevalence. Unfortunately, therapies that have been efficacious in patients with HF with reduced ejection fraction (HFrEF) have not convincingly shown a reduction in cardiovascular m