Zobrazeno 1 - 10
of 204
pro vyhledávání: '"John S Welch"'
Autor:
Ariane Lozac’hmeur, Tyler Danek, Qidi Yang, Mario G. Rosasco, John S. Welch, William Y. Go, Eric W. Ng, Armen Mardiros, David G. Maloney, Edward B. Garon, Kedar Kirtane, Diane M. Simeone, Julian R. Molina, Ameen A. Salahudeen, Michelle M. Stein, J. Randolph Hecht
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-9 (2024)
Abstract To enable interrogation of tumor HLA LOH as a clinical diagnostic for precision oncology, we developed and validated an assay that detects HLA LOH within the context of an FDA-approved clinical diagnostic test, Tempus xT CDx. Validation was
Externí odkaz:
https://doaj.org/article/b996755a54b34fbbaaef8cbd5b2d5b9a
Autor:
Christopher A Miller, Brian S White, Nathan D Dees, Malachi Griffith, John S Welch, Obi L Griffith, Ravi Vij, Michael H Tomasson, Timothy A Graubert, Matthew J Walter, Matthew J Ellis, William Schierding, John F DiPersio, Timothy J Ley, Elaine R Mardis, Richard K Wilson, Li Ding
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 8, p e1003665 (2014)
The sensitivity of massively-parallel sequencing has confirmed that most cancers are oligoclonal, with subpopulations of neoplastic cells harboring distinct mutations. A fine resolution view of this clonal architecture provides insight into tumor het
Externí odkaz:
https://doaj.org/article/513fe959e2924b31a6a0830661bda655
Autor:
Lukas D Wartman, John S Welch, Geoffrey L Uy, Jeffery M Klco, Tamara Lamprecht, Nobish Varghese, Rakesh Nagarajan, Timothy J Ley
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46529 (2012)
Because PML-RARA-induced acute promyelocytic leukemia (APL) is a morphologically differentiated leukemia, many groups have speculated about whether its leukemic cell of origin is a committed myeloid precursor (e.g. a promyelocyte) versus an hematopoi
Externí odkaz:
https://doaj.org/article/ecd7128d4bc543089c7d93944aa17360
Autor:
Agata Gruszczynska, Abhishek Maiti, Christopher A. Miller, Sai Mukund Ramakrishnan, Daniel C. Link, Geoffrey L. Uy, Allegra A. Petti, Kala Hayes, Courtney D. DiNardo, Farhad Ravandi, Timothy J. Ley, David H. Spencer, Feng Gao, Marina Y. Konopleva, John S. Welch
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/68bab4a8237f41da908adeab2a2bab9b
Autor:
Francesca Ferraro, Agata Gruszczynska, Marianna B. Ruzinova, Christopher A. Miller, Mary Elizabeth Percival, Geoffrey L. Uy, Iskra Pusic, Meagan A. Jacoby, Mathew J. Christopher, Miriam Y. Kim, Peter Westervelt, Amanda F. Cashen, Mark A. Schroeder, John F. DiPersio, Camille N. Abboud, Lukas D. Wartman, Feng Gao, Daniel C. Link, Timothy J. Ley, John S. Welch
Publikováno v:
Haematologica, Vol 107, Iss 7 (2022)
Externí odkaz:
https://doaj.org/article/a2116fd8e43648e69c98851780c8a622
Autor:
Margaret A. Ferris, John S. Welch
Publikováno v:
Haematologica, Vol 107, Iss 11 (2022)
Externí odkaz:
https://doaj.org/article/3b2e1fd147884fe5b464c39a6369028f
Autor:
Orsola di Martino, Margaret A. Ferris, Gayla Hadwiger, Soyi Sarkar, Anh Vu, María P. Menéndez-Gutiérrez, Mercedes Ricote, John S. Welch
Publikováno v:
Haematologica, Vol 107, Iss 2 (2021)
RARA and RXRA contribute to myeloid maturation in both mice and humans, and deletion of Rxra and Rxrb augments leukemic growth in mice. While defining the domains of RXRA that are required for anti-leukemic effects in murine KMT2A-MLLT3 leukemia cell
Externí odkaz:
https://doaj.org/article/99911872655e4fbfb39f20eaddcb28f4
Autor:
Orsola di Martino, Haixia Niu, Gayla Hadwiger, Heikki Kuusanmaki, Margaret A. Ferris, Anh Vu, Jeremy Beales, Carl Wagner, María P. Menéndez-Gutiérrez, Mercedes Ricote, Caroline Heckman, John S. Welch
Publikováno v:
Haematologica, Vol 106, Iss 4 (2021)
Retinoid therapy transformed response and survival outcomes in acute promyelocytic leukemia (APL), but has demonstrated only modest activity in non-APL forms of acute myeloid leukemia (AML). The presence of natural retinoids in vivo could influence t
Externí odkaz:
https://doaj.org/article/256db8d3fa8a4ed9b170d40d2797103f
Autor:
John S. Welch
Publikováno v:
Haematologica, Vol 105, Iss 12 (2020)
Externí odkaz:
https://doaj.org/article/c7a7871969f647c1b62f56bf77f6c643
Autor:
Abhishek Maiti, Caitlin R. Rausch, Jorge E. Cortes, Naveen Pemmaraju, Naval G. Daver, Farhad Ravandi, Guillermo Garcia-Manero, Gautam Borthakur, Kiran Naqvi, Maro Ohanian, Nicholas J. Short, Yesid Alvarado, Tapan M. Kadia, Koichi Takahashi, Musa Yilmaz, Nitin Jain, Steven Kornblau, Guillermo Montalban Bravo, Koji Sasaki, Michael Andreeff, Prithiviraj Bose, Alessandra Ferrajoli, Ghayas C. Issa, Elias J. Jabbour, Lucia Masarova, Philip A. Thompson, Sa Wang, Sergej Konoplev, Sherry A. Pierce, Jing Ning, Wei Qiao, John S. Welch, Hagop M. Kantarjian, Courtney D. DiNardo, Marina Y. Konopleva
Publikováno v:
Haematologica, Vol 106, Iss 3 (2020)
Externí odkaz:
https://doaj.org/article/2a6229a076e94c6d8911ec46d960e74d