Zobrazeno 1 - 10
of 166
pro vyhledávání: '"John S Thornton"'
Autor:
Enrico De Vita, Gerard R Ridgway, Mark J White, Marie-Claire Porter, Diana Caine, Peter Rudge, John Collinge, Tarek A Yousry, Hans Rolf Jager, Simon Mead, John S Thornton, Harpreet Hyare
Publikováno v:
NeuroImage: Clinical, Vol 13, Iss C, Pp 89-96 (2017)
Purpose: MRI has become an essential tool for prion disease diagnosis. However there exist only a few serial MRI studies of prion patients, and these mostly used whole brain summary measures or region of interest based approaches. We present here the
Externí odkaz:
https://doaj.org/article/e2007be9ba7f44078a6f0132f19ea11f
Autor:
Jasper M. Morrow, Sachit Shah, Lara Cristiano, Matthew R. B. Evans, Carolynne M. Doherty, Talal Alnaemi, Abeer Saab, Ahmed Emira, Uros Klickovic, Ahmed Hammam, Afnan Altuwaijri, Stephen Wastling, Mary M. Reilly, Michael G. Hanna, Tarek A. Yousry, John S. Thornton
Publikováno v:
European Radiology Experimental, Vol 8, Iss 1, Pp 1-12 (2024)
Abstract Background Magnetic resonance imaging (MRI) quantification of intramuscular fat accumulation is a responsive biomarker in neuromuscular diseases. Despite emergence of automated methods, manual muscle segmentation remains an essential foundat
Externí odkaz:
https://doaj.org/article/29a6b7777ec4436dbf62ecd5e9df90c4
Autor:
Valeria Ricotti, Matthew R B Evans, Christopher D J Sinclair, Jordan W Butler, Deborah A Ridout, Jean-Yves Hogrel, Ahmed Emira, Jasper M Morrow, Mary M Reilly, Michael G Hanna, Robert L Janiczek, Paul M Matthews, Tarek A Yousry, Francesco Muntoni, John S Thornton
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162542 (2016)
A number of promising experimental therapies for Duchenne muscular dystrophy (DMD) are emerging. Clinical trials currently rely on invasive biopsies or motivation-dependent functional tests to assess outcome. Quantitative muscle magnetic resonance im
Externí odkaz:
https://doaj.org/article/19bd8f41fda140849f988d7494cfbc4e
Autor:
Joerg eMagerkurth, Laura eMancini, William ePenny, Guillaume eFlandin, John eAshburner, Caroline eMicallef, Enrico eDe Vita, Pankaj eDaga, Mark eWhite, Craig eBuckley, Adam Kenji Yamamoto, Sebastien eOurselin, Tarek eYousry, John S Thornton, Nikolaus eWeiskopf
Publikováno v:
Frontiers in Neuroscience, Vol 9 (2015)
Functional MRI (fMRI) used for neurosurgical planning delineates functionally eloquent brain areas by time-series analysis of task-induced BOLD signal changes. Commonly used frequentist statistics protect against false positive results based on a p-v
Externí odkaz:
https://doaj.org/article/d6be5909fe004a7a998a986f09e86f83
Autor:
Tracey A Willis, Kieren G Hollingsworth, Anna Coombs, Marie-Louise Sveen, Soren Andersen, Tanya Stojkovic, Michelle Eagle, Anna Mayhew, Paulo Loureiro de Sousa, Liz Dewar, Jasper M Morrow, Christopher D J Sinclair, John S Thornton, Kate Bushby, Hanns Lochmuller, Michael G Hanna, Jean-Yves Hogrel, Pierre G Carlier, John Vissing, Volker Straub
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e90377 (2014)
We conducted a prospective multinational study of muscle pathology using magnetic resonance imaging (MRI) in patients with limb-girdle muscular dystrophy 2I (LGMD2I). Thirty eight adult ambulant LGMD2I patients (19 male; 19 female) with genetically i
Externí odkaz:
https://doaj.org/article/809289b1bcdc4a229f182469ffcb1256
Autor:
Tracey A Willis, Kieren G Hollingsworth, Anna Coombs, Marie-Louise Sveen, Søren Andersen, Tanya Stojkovic, Michelle Eagle, Anna Mayhew, Paulo L de Sousa, Liz Dewar, Jasper M Morrow, Christopher D J Sinclair, John S Thornton, Kate Bushby, Hanns Lochmüller, Michael G Hanna, Jean-Yves Hogrel, Pierre G Carlier, John Vissing, Volker Straub
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70993 (2013)
Outcome measures for clinical trials in neuromuscular diseases are typically based on physical assessments which are dependent on patient effort, combine the effort of different muscle groups, and may not be sensitive to progression over short trial
Externí odkaz:
https://doaj.org/article/52f1434bf16d451bb2e6f4224e501642
Autor:
Josh Kahan, Laura Mancini, Maren Urner, Karl Friston, Marwan Hariz, Etienne Holl, Mark White, Diane Ruge, Marjan Jahanshahi, Tessel Boertien, Tarek Yousry, John S Thornton, Patricia Limousin, Ludvic Zrinzo, Tom Foltynie
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50270 (2012)
Deep brain stimulation of the subthalamic nucleus (STN DBS) has become an accepted treatment for patients experiencing the motor complications of Parkinson's disease (PD). While its successes are becoming increasingly apparent, the mechanisms underly
Externí odkaz:
https://doaj.org/article/69b1cf84bed54fc4b76def7a0c2f7361
Autor:
Didier Laurent, Jon Riek, Christopher D.J. Sinclair, Parul Houston, Ronenn Roubenoff, Dimitris A. Papanicolaou, Attila Nagy, Steve Pieper, Tarek A. Yousry, Michael G. Hanna, John S. Thornton, Pedro M. Machado
Publikováno v:
Neurology. 99:e865-e876
Background and ObjectivesLimited data suggest that quantitative MRI (qMRI) measures have potential to be used as trial outcome measures in sporadic inclusion body myositis (sIBM) and as a noninvasive assessment tool to study sIBM muscle pathologic pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6139258528aa9f491898445d5ceb9e38
https://doi.org/10.1212/wnl.0000000000200776
https://doi.org/10.1212/wnl.0000000000200776
Autor:
Luke Francis O'Donnell, Andrea Cortese, Alexander M Rossor, Matilde Laura, Julian Blake, Mariola Skorupinska, Michael P Lunn, John S Thornton, Riccardo Currò, Jasper M Morrow, Mary M Reilly
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 94:88-90
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c12a21e92569172a9beddba0e69e8f
https://doi.org/10.1136/jnnp-2022-329432
https://doi.org/10.1136/jnnp-2022-329432
Publikováno v:
Magnetic resonance in medicineREFERENCES.
Quantitative susceptibility mapping (QSM) is used increasingly for clinical research where oblique image acquisition is commonplace, but its effects on QSM accuracy are not well understood.The QSM processing pipeline involves defining the unit magnet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85dafca0ca12e0a1ccff3d36bf3a7f94
https://pubmed.ncbi.nlm.nih.gov/36480002
https://pubmed.ncbi.nlm.nih.gov/36480002