Zobrazeno 1 - 10
of 51
pro vyhledávání: '"John S Stahl"'
Autor:
John S Stahl, Zachary C Thumser
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57895 (2013)
The potassium channel antagonist 4-aminopyridine (4-AP) improves a variety of motor abnormalities associated with disorders of the cerebellum. The most rigorous quantitative data relate to 4-AP's ability to improve eye movement deficits in humans ref
Externí odkaz:
https://doaj.org/article/83fd276d22b14faa84db1eab9ff8214a
Publikováno v:
Cerebellum (London, England). 21(6)
Purkinje cells (PCs) in the cerebellar flocculus carry rate-coded information that ultimately drives eye movement. Floccular PCs lying nearby each other exhibit partial synchrony of their simple spikes (SS). Elsewhere in the cerebellum, PC SS synchro
Publikováno v:
Anat Rec (Hoboken)
The organization of extraocular muscles (EOMs) and their motor nuclei was investigated in the mouse due to the increased importance of this model for oculomotor research. Mice showed a standard EOM organization pattern, although their eyes are set at
Autor:
Zachary C. Thumser, John S. Stahl, Sean R. Anderson, Paul Dean, Francisco H. Andrade, Paul J. May
Publikováno v:
Journal of Neurophysiology. 114:1455-1467
Rigorous descriptions of ocular motor mechanics are often needed for models of ocular motor circuits. The mouse has become an important tool for ocular motor studies, yet most mechanical data come from larger species. Recordings of mouse abducens neu
Autor:
John S. Stahl, Zachary C. Thumser
Publikováno v:
Human Movement Science. 32:1-8
Numerous studies have reported the ability of mobile phones to distract users and thereby degrade performance of concurrent tasks. Less is known about whether the phone-holding posture can itself influence concurrent motor activities. Horizontal eye
Publikováno v:
Journal of Vestibular Research. 22:221-241
Downbeat nystagmus (DBN) is a common eye movement complication of cerebellar disease. Use of mice to study pathophysiology of vestibulocerebellar disease is increasing, but it is unclear if mice can be used to study DBN; it has not been reported in t
Autor:
John S. Stahl, Zachary C. Thumser
Publikováno v:
Experimental Brain Research. 195:393-401
Humans exhibit considerable individuality in their propensity to make head movements during horizontal saccades. These variations originate in multiple quantifiable characteristics, including individuals' preferred ranges of gaze, eye-in-head, and he
Publikováno v:
Journal of Neurophysiology, 95(3), 1588-1607. American Physiological Society
Mice carrying mutations of the gene encoding the ion pore of the P/Q calcium channel (Cacna1a) are an instance in which cerebellar dysfunction may be attributable to altered electrophysiology and thus provide an opportunity to study how neuronal intr
Publikováno v:
Experimental Brain Research. 155:9-18
Mammals with foveas (or analogous retinal specializations) frequently shift gaze without moving the head, and their behavior contrasts sharply with "afoveate" mammals, in which eye and head movements are strongly coupled. The ability to move the eyes
Publikováno v:
Annals of the New York Academy of Sciences. 956:430-433