Zobrazeno 1 - 10
of 132
pro vyhledávání: '"John S Oxford"'
Autor:
Rob Lambkin-Williams, Colin Gelder, Richard Broughton, Corey P Mallett, Anthony S Gilbert, Alex Mann, David He, John S Oxford, David Burt
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0163089 (2016)
A Proteosome-adjuvanted trivalent inactivated influenza vaccine (P-TIV) administered intra-nasally was shown to be safe, well tolerated and immunogenic in both systemic and mucosal compartments, and effective at preventing illness associated with evi
Externí odkaz:
https://doaj.org/article/2f97a21b47f74354907b28ad87dd25ce
Autor:
Alex J Mann, Nicolas Noulin, Andrew Catchpole, Koert J Stittelaar, Leon de Waal, Edwin J B Veldhuis Kroeze, Michael Hinchcliffe, Alan Smith, Emanuele Montomoli, Simona Piccirella, Albert D M E Osterhaus, Alastair Knight, John S Oxford, Giulia Lapini, Rebecca Cox, Rob Lambkin-Williams
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e93761 (2014)
We investigated the protective efficacy of two intranasal chitosan (CSN and TM-CSN) adjuvanted H5N1 Influenza vaccines against highly pathogenic avian Influenza (HPAI) intratracheal and intranasal challenge in a ferret model. Six groups of 6 ferrets
Externí odkaz:
https://doaj.org/article/36bbfb15eb674f50b47050f2bd12c9a0
Autor:
Alastair J Moss, Fiona P Gaughran, Aliyye Karasu, Anthony S Gilbert, Alex J Mann, Colin M Gelder, John S Oxford, Henry A Stephens, Rob Lambkin-Williams
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71376 (2013)
Influenza is a major cause of morbidity and mortality. Despite vaccination, many elderly recipients do not develop a protective antibody response. To determine whether Human Leukocyte Antigen (HLA) alleles modulate seroprotection to influenza, a coho
Externí odkaz:
https://doaj.org/article/ac9d56ab79864081bf4a5badb10d74f6
Autor:
John S. Oxford, Douglas Gill
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 9, Pp 2051-2055 (2020)
In 1914, the concept of a prophylactic vaccine, administered to a person before the disease had been contracted, was still controversial. Nevertheless, Almroth Wright tested new pneumococcus vaccines in South Africa, where the incidence of bacterial
Externí odkaz:
https://doaj.org/article/2e4237e510454eae9e16d09bb6dac46c
Autor:
John S. Oxford, Douglas Gill
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 15, Iss 9, Pp 2009-2012 (2019)
When we reconsider the virology and history of the Spanish Influenza Pandemic, the science of 2018 provides us with tools which did not exist at the time. Two such tools come to mind. The first lies in the field of ‘gain of function’ experiments.
Externí odkaz:
https://doaj.org/article/1eea6cdb96c24dd2b3572d78cea1fe70
Autor:
Douglas Gill, John S. Oxford
Publikováno v:
Human Vaccines & Immunotherapeutics
When we reconsider the virology and history of the Spanish Influenza Pandemic, the science of 2018 provides us with tools which did not exist at the time. Two such tools come to mind. The first lies in the field of ‘gain of function’ experiments.
Autor:
Barry Clinch, Pedro A. Piedra, Zuzana Dobbie, Edward C. Holmes, Aeron C. Hurt, John S. Oxford
Publikováno v:
Clin Microbiol Rev
SUMMARYInfluenza poses a significant burden on society and health care systems. Although antivirals are an integral tool in effective influenza management, the potential for the emergence of antiviral-resistant viruses can lead to uncertainty and hes
Autor:
Douglas Gill, John S. Oxford
Publikováno v:
The Lancet Infectious Diseases. 18:e348-e354
The influenza epidemic of 1918 represented the greatest failure of medical science in the 20th century. Fortunately, research throughout subsequent years has been making amends. Some studies have applied RT-PCR to the tissue samples from that time, w
Autor:
Adriana Pistol, Ariel Beresniak, John S. Oxford, Christian Napoli, Massimo Fabiani, Marta Barral, Dominique Bremond, Christos Lionis, Stéphane Bonnevay, Laurent Niddam, Charmaine Gauci, Ahmed Bounekkar, Paweł Goryński, Caterina Rizzo
Publikováno v:
Università di Pisa-IRIS
Background The FLURESP project is a public health project funded by the European Commission with the objective to design a methodological approach in order to compare the cost-effectiveness of existing public health measures against human influenza p