Zobrazeno 1 - 10
of 39
pro vyhledávání: '"John S Ng"'
Publikováno v:
J Pediatr Pharmacol Ther
OBJECTIVE The purpose of this study was to evaluate the efficacy of a standardized premedication and therapeutic drug monitoring (TDM) protocol to prevent hypersensitivity reactions from pegaspargase infusions. Pegaspargase is an essential therapeuti
Publikováno v:
The Journal of Pediatric Pharmacology and Therapeutics. 25:246-250
OBJECTIVES Adequate hydration status prior to chemotherapy initiation prevents nephrotoxicity in patients receiving potentially nephrotoxic regimens. The purpose of this study was to evaluate the time to initiation of ifosfamide administration betwee
Publikováno v:
The Journal of Pediatric Pharmacology and Therapeutics. 24:528-533
Posaconazole is a lipophilic triazole antifungal that exhibits variable absorption when administered orally. It possesses a broad spectrum of activity against various fungi, such as Aspergillus and traditionally resistant molds such as Rhizopus and M
Autor:
Tosha A Egelund, Lauren Pommert, Nicole Liberio, John S Ng, Molly J Siver, Michael J. Burke, Howard M. Katzenstein
Publikováno v:
Journal of pediatric hematology/oncology. 43(2)
Imatinib, a tyrosine kinase inhibitor has improved survival in pediatric patients with Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia. There are no formal drug interactions listed between methotrexate and tyrosine kinase inhibit
Publikováno v:
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 33:e1-e8
Posaconazole is a triazole antifungal agent used as adjuvant or salvage therapy for the treatment of zygomycosis, an invasive fungal infection associated with high mortality. Oral posaconazole absorption is highly variable. We describe the pharmacoki
Methemoglobinemia induced by rasburicase in a pediatric patient: A case report and literature review
Publikováno v:
Journal of Oncology Pharmacy Practice. 18:425-431
Rasburicase is a recombinant urate oxidase enzyme indicated for tumor lysis syndrome (TLS), a potential life-threatening oncologic emergency that occurs most commonly during chemotherapy for hematological malignancies. As a result of the defects in t
Autor:
John S Ng
Publikováno v:
Journal of Oncology Pharmacy Practice. 17:209-224
Objective: To review the pharmacology, pharmacokinetics, in vitro and in vivo efficacy, and safety profile of vinflunine in the treatment of various solid tumors. Data sources: A literature search was conducted using keywords included vinflunine, vin
Autor:
Devan V. Mehrotra, Liu Chin, James R. Behling, Chung H. Yen, Kalim S. Fuzail, John S. Ng, and Edward E. Yonan, Arthur Lee Campbell
Publikováno v:
Organic Process Research & Development. 1:45-54
An efficient large-scale process to prepare the HIV protease inhibitor urea intermediate, N-[3(S)-[bis(phenylmethyl)amino-2(R)-hydroxy-4-phenylbutyl]-N ‘-(1,1-dimethylethyl)-N-(2methylpropyl)urea w...
Publikováno v:
Tetrahedron. 51:6397-6410
A practical and efficient synthesis of an HIV protease inhibitor intermediate has been developed based on the diastereoselective epoxide formation from a chiral α-aminoaldehyde and an in situ generated halomethyllithium reagent.
Autor:
George W. J. Fleet, Kevin A. Babiak, Medich John R, Payman Farid, Arthur Lee Campbell, James R. Behling, John S. Ng
Publikováno v:
ChemInform. 24