Zobrazeno 1 - 10
of 376
pro vyhledávání: '"John S Mattick"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Convolutional Neural Networks (CNNs) have been central to the Deep Learning revolution and played a key role in initiating the new age of Artificial Intelligence. However, in recent years newer architectures such as Transformers have dominat
Externí odkaz:
https://doaj.org/article/35d2510217d742bbbe6458a2591b8c37
Autor:
John S Mattick
Publikováno v:
eLife, Vol 2 (2013)
Genetic knockout experiments on mice confirm that some long noncoding RNA molecules have developmental functions.
Externí odkaz:
https://doaj.org/article/a639df1275c9474592622fb4bc45839e
Autor:
Chanel E Smart, Marjan E Askarian Amiri, Ania Wronski, Marcel E Dinger, Joanna Crawford, Dmitry A Ovchinnikov, Ana Cristina Vargas, Lynne Reid, Peter T Simpson, Sarah Song, Christiane Wiesner, Juliet D French, Richa K Dave, Leonard da Silva, Amy Purdon, Megan Andrew, John S Mattick, Sunil R Lakhani, Melissa A Brown, Stuart Kellie
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40742 (2012)
The protein tyrosine phosphatase receptor J, PTPRJ, is a tumor suppressor gene that has been implicated in a range of cancers, including breast cancer, yet little is known about its role in normal breast physiology or in mammary gland tumorigenesis.
Externí odkaz:
https://doaj.org/article/d5eaa5f72a81446caa82d85295dc8909
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43699 (2012)
Australian funnel-web spiders are generally considered the most dangerous spiders in the world, with envenomations from the Sydney funnel-web spider Atrax robustus resulting in at least 14 human fatalities prior to the introduction of an effective an
Externí odkaz:
https://doaj.org/article/25594870aa6a4bb4b7c13858197408b7
Autor:
Michael B Clark, Paulo P Amaral, Felix J Schlesinger, Marcel E Dinger, Ryan J Taft, John L Rinn, Chris P Ponting, Peter F Stadler, Kevin V Morris, Antonin Morillon, Joel S Rozowsky, Mark B Gerstein, Claes Wahlestedt, Yoshihide Hayashizaki, Piero Carninci, Thomas R Gingeras, John S Mattick
Publikováno v:
PLoS Biology, Vol 9, Iss 7, p e1000625; discussion e1001102 (2011)
Externí odkaz:
https://doaj.org/article/0c29d3480ead4effa96e474f417fd1d0
Autor:
Fernando Faunes, Natalia Sanchez, Mauricio Moreno, Gonzalo H Olivares, Dasfne Lee-Liu, Leonardo Almonacid, Alex W Slater, Tomas Norambuena, Ryan J Taft, John S Mattick, Francisco Melo, Juan Larrain
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22569 (2011)
Transposable elements comprise a large proportion of animal genomes. Transposons can have detrimental effects on genome stability but also offer positive roles for genome evolution and gene expression regulation. Proper balance of the positive and de
Externí odkaz:
https://doaj.org/article/ddbe784aa23d46539742456264058b6a
Autor:
John S Mattick
Publikováno v:
PLoS Genetics, Vol 5, Iss 4, p e1000459 (2009)
The majority of the genome in animals and plants is transcribed in a developmentally regulated manner to produce large numbers of non-protein-coding RNAs (ncRNAs), whose incidence increases with developmental complexity. There is growing evidence tha
Externí odkaz:
https://doaj.org/article/4e36eb06afa24d0e97de7c87397e6052
Publikováno v:
PLoS Computational Biology, Vol 4, Iss 11, p e1000176 (2008)
The assumption that RNA can be readily classified into either protein-coding or non-protein-coding categories has pervaded biology for close to 50 years. Until recently, discrimination between these two categories was relatively straightforward: most
Externí odkaz:
https://doaj.org/article/93919d3375964c7b83ac10be8a57c50b
Publikováno v:
PLoS ONE, Vol 2, Iss 11, p e1133 (2007)
BackgroundMicroRNAs (miRNAs) are short non-coding RNAs that regulate differentiation and development in many organisms and play an important role in cancer.Methodology/principal findingsUsing a public database of mapped retroviral insertion sites fro
Externí odkaz:
https://doaj.org/article/0db3122736d0459ca90febf5a874625d
Autor:
Masaaki Furuno, Ken C Pang, Noriko Ninomiya, Shiro Fukuda, Martin C Frith, Carol Bult, Chikatoshi Kai, Jun Kawai, Piero Carninci, Yoshihide Hayashizaki, John S Mattick, Harukazu Suzuki
Publikováno v:
PLoS Genetics, Vol 2, Iss 4, p e37 (2006)
Non-protein-coding RNAs (ncRNAs) are increasingly being recognized as having important regulatory roles. Although much recent attention has focused on tiny 22- to 25-nucleotide microRNAs, several functional ncRNAs are orders of magnitude larger in si
Externí odkaz:
https://doaj.org/article/90c32b0d57dc4c4fa87080183428175c