Zobrazeno 1 - 10
of 60
pro vyhledávání: '"John S L Parker"'
Autor:
Yingying Guo, Meleana M Hinchman, Mercedes Lewandrowski, Shaun T Cross, Danica M Sutherland, Olivia L Welsh, Terence S Dermody, John S L Parker
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009494 (2021)
The mammalian orthoreovirus double-stranded (ds) RNA-binding protein σ3 is a multifunctional protein that promotes viral protein synthesis and facilitates viral entry and assembly. The dsRNA-binding capacity of σ3 correlates with its capacity to pr
Externí odkaz:
https://doaj.org/article/beff01e7b3dc4af685b9ca3285681dad
Publikováno v:
PLoS Pathogens, Vol 4, Iss 12, p e1000248 (2008)
Apoptosis plays an important role in the pathogenesis of reovirus encephalitis. Reovirus outer-capsid protein mu1, which functions to penetrate host cell membranes during viral entry, is the primary regulator of apoptosis following reovirus infection
Externí odkaz:
https://doaj.org/article/02c920671777479bb792dcd2854133e2
Autor:
Santiago Peralta, Jennifer K. Grenier, Suzin M. Webb, Andrew D. Miller, Ileana C. Miranda, John S. L. Parker
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Feline chronic gingivostomatitis (FCGS) is a relatively common and debilitating disease characterized by bilateral inflammation and ulceration of the caudal oral mucosa, alveolar and buccal mucosa, and varying degrees of periodontal disease.
Externí odkaz:
https://doaj.org/article/65731c6d30aa4732bad789c79a45899a
Publikováno v:
Journal of the American Veterinary Medical Association. :1-5
OBJECTIVE To characterize and compare the careers of alumni of the Cornell Leadership Program for Veterinary Students according to the countries where they studied and obtained their veterinary qualification. The Cornell Leadership Program is a 10-we
Autor:
David W. McKellar, Madhav Mantri, Meleana M. Hinchman, John S. L. Parker, Praveen Sethupathy, Benjamin D. Cosgrove, Iwijn De Vlaminck
Publikováno v:
Nature Biotechnology. 41:513-520
Spatial transcriptomics reveals the spatial context of gene expression, but current methods are limited to assaying polyadenylated (A-tailed) RNA transcripts. Here we demonstrate that enzymatic in situ polyadenylation of RNA enables detection of the
Autor:
David B. Kushner, Troy D. Cline, Pranav Danthi, Kari M. Debbink, Maureen C. Ferran, Michelle Flenniken, Dylan M. Johnson, Andrew Mehle, Daniel A. Morales, Suchetana Mukhopadhyay, John S. L. Parker, Chelsey C. Spriggs, Lauren A. O’Donnell, Melissa S. Maginnis
Publikováno v:
J Virol
Curriculum guidelines for virology are needed to best guide student learning due to the continuous and ever-increasing volume of virology information, the need to ensure that undergraduate and graduate students have a foundational understanding of ke
Autor:
John S. L. Parker, Cristina Risco, Raquel Tenorio, Gwen M. Taylor, Krishnan Raghunathan, Christopher H Lee, Isabel Fernández de Castro, Andrea J. French, Terence S. Dermody
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
mBio
mBio
The function of the mammalian orthoreovirus (reovirus) σNS nonstructural protein is enigmatic. σNS is an RNA-binding protein that forms oligomers and enhances the stability of bound RNAs, but the mechanisms by which it contributes to reovirus repli
Autor:
Danica M. Sutherland, Yingying Guo, John S. L. Parker, Mercedes Lewandrowski, Shaun T. Cross, Olivia L. Welsh, Terence S. Dermody, Meleana M. Hinchman
The mammalian orthoreovirus double-stranded (ds) RNA binding protein {sigma}3 is a multifunctional protein that promotes viral protein synthesis and facilitates viral entry and assembly. The dsRNA-binding capacity of {sigma}3 correlates with its capa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5480839a4ac39d81247420fbda55caf2
https://doi.org/10.1101/2021.03.22.436456
https://doi.org/10.1101/2021.03.22.436456
Autor:
Yingying Guo, John S. L. Parker
Publikováno v:
Viruses, Vol 13, Iss 275, p 275 (2021)
Viruses
Viruses
De novo viral protein synthesis following entry into host cells is essential for viral replication. As a consequence, viruses have evolved mechanisms to engage the host translational machinery while at the same time avoiding or counteracting host def
Publikováno v:
J Virol
Induction of necroptosis by mammalian reovirus requires both type I interferon (IFN)-signaling and viral replication events that lead to production of progeny genomic dsRNA. The reovirus outer capsid protein µ1 negatively regulates reovirus-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a9bee671d1944de2190ef76126606f
https://doi.org/10.1101/2020.07.19.210872
https://doi.org/10.1101/2020.07.19.210872