Zobrazeno 1 - 10
of 66
pro vyhledávání: '"John S Kaddis"'
Autor:
Catherine C. Robertson, Ruth M. Elgamal, Belle A. Henry-Kanarek, Peter Arvan, Shuibing Chen, Sangeeta Dhawan, Decio L. Eizirik, John S. Kaddis, Golnaz Vahedi, Stephen C.J. Parker, Kyle J. Gaulton, Scott A. Soleimanpour
Publikováno v:
Molecular Metabolism, Vol 86, Iss , Pp 101973- (2024)
Background: Type 1 diabetes (T1D) is a complex multi-system disease which arises from both environmental and genetic factors, resulting in the destruction of insulin-producing pancreatic beta cells. Over the past two decades, human genetic studies ha
Externí odkaz:
https://doaj.org/article/2fd0a447e207481d8751377f9c298a7a
Autor:
Daniel J. Perry, Melanie R. Shapiro, Sonya W. Chamberlain, Irina Kusmartseva, Srikar Chamala, Leandro Balzano-Nogueira, Mingder Yang, Jason O. Brant, Maigan Brusko, MacKenzie D. Williams, Kieran M. McGrail, James McNichols, Leeana D. Peters, Amanda L. Posgai, John S. Kaddis, Clayton E. Mathews, Clive H. Wasserfall, Bobbie-Jo M. Webb-Robertson, Martha Campbell-Thompson, Desmond Schatz, Carmella Evans-Molina, Alberto Pugliese, Patrick Concannon, Mark S. Anderson, Michael S. German, Chester E. Chamberlain, Mark A. Atkinson, Todd M. Brusko
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-16 (2023)
Abstract The Network for Pancreatic Organ donors with Diabetes (nPOD) is the largest biorepository of human pancreata and associated immune organs from donors with type 1 diabetes (T1D), maturity-onset diabetes of the young (MODY), cystic fibrosis-re
Externí odkaz:
https://doaj.org/article/0ad4cb66140840c5abd02c69201bad7b
Autor:
Léon van Gurp, Leon Fodoulian, Daniel Oropeza, Kenichiro Furuyama, Eva Bru-Tari, Anh Nguyet Vu, John S. Kaddis, Iván Rodríguez, Fabrizio Thorel, Pedro L. Herrera
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/c9bad23815644e399854264568da3129
Autor:
Léon van Gurp, Leon Fodoulian, Daniel Oropeza, Kenichiro Furuyama, Eva Bru-Tari, Anh Nguyet Vu, John S. Kaddis, Iván Rodríguez, Fabrizio Thorel, Pedro L. Herrera
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Abstract Generation of surrogate cells with stable functional identities is crucial for developing cell-based therapies. Efforts to produce insulin-secreting replacement cells to treat diabetes require reliable tools to assess islet cellular identity
Externí odkaz:
https://doaj.org/article/98f4555862884fd79c46027b0e72ef4c
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280872 (2023)
Type 1 diabetes patients carrying a 'protective' insulin gene (INS) variant present a disease endotype with reduced insulin antibody titers, preserved beta cell function and improved glycemic control. We tested whether this protective INS variant ass
Externí odkaz:
https://doaj.org/article/afe7bd8fabde41a99aba687c261c606e
Autor:
Tatjana Nikolic, Jessica S. Suwandi, Joris Wesselius, Sandra Laban, Antoinette M. Joosten, Petra Sonneveld, Dick Mul, Henk-Jan Aanstoot, John S. Kaddis, Jaap Jan Zwaginga, Bart O. Roep
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionRestoration of immune tolerance may halt progression of autoimmune diseases. Tolerogenic dendritic cells (tolDC) inhibit antigen-specific proinflammatory T-cells, generate antigen-specific regulatory T-cells and promote IL-10 production i
Externí odkaz:
https://doaj.org/article/6b30cbbe941d482d958e523b9eb75cf6
Autor:
John S. Kaddis, Layla Rouse, Audrey V. Parent, Diane C. Saunders, Anath Shalev, Cherie L. Stabler, Doris A. Stoffers, Bridget K. Wagner, Joyce C. Niland
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101283- (2021)
Externí odkaz:
https://doaj.org/article/4b11df8c757349c58bcb1ec2250baff0
Autor:
Meirigeng Qi, John S. Kaddis, Kuan-Tsen Chen, Jeffrey Rawson, Keiko Omori, Zhen Bouman Chen, Sangeeta Dhawan, Jeffrey S. Isenberg, Fouad Kandeel, Bart O. Roep, Ismail H. Al-Abdullah
Publikováno v:
PLoS ONE, Vol 16, Iss 10 (2021)
We investigated the effect of chronic marijuana use, defined as 4 times weekly for more than 3 years, on human pancreatic islets. Pancreata from deceased donors who chronically used marijuana were compared to those from age, sex and ethnicity matched
Externí odkaz:
https://doaj.org/article/4b7a770ce1a7403aa1ed7fa083396837
Autor:
Courtney W. Houchen, Guangyu An, Michael S. Bronze, James J. Tomasek, Kenneth J. Vega, Edwin Bannerman-Menson, Parthasarathy Chandrakesan, Randal May, William L. Berry, John S. Kaddis, Dongfeng Qu, Yang Ge, Nathaniel Weygant
Doublecortin-like kinase 1 (DCLK1) is a gastrointestinal (GI) tuft cell kinase that has been investigated as a biomarker of cancer stem–like cells in colon and pancreatic cancers. However, its utility as a biomarker may be limited in principle by s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c03fd1353a0072c3e8aaed339ddd654
https://doi.org/10.1158/0008-5472.c.6508002
https://doi.org/10.1158/0008-5472.c.6508002
Autor:
Courtney W. Houchen, Guangyu An, Michael S. Bronze, James J. Tomasek, Kenneth J. Vega, Edwin Bannerman-Menson, Parthasarathy Chandrakesan, Randal May, William L. Berry, John S. Kaddis, Dongfeng Qu, Yang Ge, Nathaniel Weygant
A separate file containging supplemental figure legends as requested by the editorial office
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ba582a769c646e0dfd4a41d5eb6985
https://doi.org/10.1158/0008-5472.22410486.v1
https://doi.org/10.1158/0008-5472.22410486.v1