Zobrazeno 1 - 10
of 70
pro vyhledávání: '"John S Beech"'
Autor:
Veerle Kersemans, John S Beech, Stuart Gilchrist, Paul Kinchesh, Philip D Allen, James Thompson, Ana L Gomes, Zenobia D'Costa, Luke Bird, Iain D C Tullis, Robert G Newman, Aurelien Corroyer-Dulmont, Nadia Falzone, Abul Azad, Katherine A Vallis, Owen J Sansom, Ruth J Muschel, Borivoj Vojnovic, Mark A Hill, Emmanouil Fokas, Sean C Smart
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176693 (2017)
Preclinical CT-guided radiotherapy platforms are increasingly used but the CT images are characterized by poor soft tissue contrast. The aim of this study was to develop a robust and accurate method of MRI-guided radiotherapy (MR-IGRT) delivery to ab
Externí odkaz:
https://doaj.org/article/ae518cca3a5a4ee6a6bf6b30edf910b8
Autor:
Veerle Kersemans, Pavitra Kannan, John S Beech, Russell Bates, Benjamin Irving, Stuart Gilchrist, Philip D Allen, James Thompson, Paul Kinchesh, Christophe Casteleyn, Julia Schnabel, Mike Partridge, Ruth J Muschel, Sean C Smart
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128537 (2015)
Preclinical in vivo CT is commonly used to visualise vessels at a macroscopic scale. However, it is prone to many artefacts which can degrade the quality of CT images significantly. Although some artefacts can be partially corrected for during image
Externí odkaz:
https://doaj.org/article/ed6f36bc39f44202a4c525d14f8c532a
Autor:
Daniel W Wheeler, Andrew J Thompson, Federico Corletto, Jill Reckless, Justin C T Loke, Nicolas Lapaque, Andrew J Grant, Pietro Mastroeni, David J Grainger, Claire L Padgett, John A O'Brien, Nigel G A Miller, John Trowsdale, Sarah C R Lummis, David K Menon, John S Beech
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17152 (2011)
GABA(A) receptors are members of the Cys-loop family of neurotransmitter receptors, proteins which are responsible for fast synaptic transmission, and are the site of action of wide range of drugs. Recent work has shown that Cys-loop receptors are pr
Externí odkaz:
https://doaj.org/article/23173b15fc8b4b9690a691153a3c3a03
Autor:
John S. Beech, Jack J. Miller, Veerle Kersemans, Danny Allen, Jürgen E. Schneider, Stuart Gilchrist, Borivoj Vojnovic, Paul Kinchesh, Sean Smart, Michael Brady
Publikováno v:
Magnetic Resonance Imaging
Prospective cardiac gating during MRI is hampered by electromagnetic induction from the rapidly switched imaging gradients into the ECG detection circuit. This is particularly challenging in small animal MRI, as higher heart rates combined with a sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7995b153e23f13fb92cfa35eec3a14e2
http://europepmc.org/articles/PMC8274699
http://europepmc.org/articles/PMC8274699
Autor:
Jean-Claude Baron, Franklin I. Aigbirhio, P. Simon Jones, John S. Beech, Jessica L Hughes, Dechao Wang, Tim D. Fryer, David K. Menon
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 40:1997-2009
Predicting tissue outcome early after stroke is an important goal. MRI >3 h accurately predicts infarction but is insensitive to selective neuronal loss (SNL). Previous studies suggest that chronic-stage 11 C-flumazenil PET (FMZ-PET) is a validated m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a776af61f20d697ce889ddff030b68b9
https://doi.org/10.1177/0271678x19883040
https://doi.org/10.1177/0271678x19883040
Autor:
Diana Cash, John S Beech, Elaine A. Irving, Michel Mesquita, Steve C.R. Williams, Maria Ashioti, Catherine Morgan
Publikováno v:
Neurological research. 42(10)
After cerebral ischaemia the blood-brain barrier (BBB) may be compromised and this has been observed in both clinical and preclinical studies. The timing of BBB disruption after ischaemia has long been considered to be biphasic, however some groups c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c3164438b0eacafeee512e0782a546
https://pubmed.ncbi.nlm.nih.gov/32600164
https://pubmed.ncbi.nlm.nih.gov/32600164
Autor:
Philip D. Allen, Stuart Gilchrist, Paul Kinchesh, Veerle Kersemans, Sean Smart, Borivoj Vojnovic, John S. Beech
Publikováno v:
Magnetic Resonance Imaging
Purpose To develop an MR-compatible resistive heater for temperature maintenance of anaesthetized animals. Materials and Methods An MR-compatible resistive electrical heater was formed from a tightly-wound twisted pair wire, interfaced to a homeother
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c57269311e7e4eb1cead4f95910395
https://ora.ox.ac.uk/objects/uuid:51e3920c-b8e2-42fa-9963-fed217f28fb9
https://ora.ox.ac.uk/objects/uuid:51e3920c-b8e2-42fa-9963-fed217f28fb9
Autor:
Jessica L, Hughes, John S, Beech, P Simon, Jones, Dechao, Wang, David K, Menon, Franklin I, Aigbirhio, Tim D, Fryer, Jean-Claude, Baron
Publikováno v:
J Cereb Blood Flow Metab
Predicting tissue outcome early after stroke is an important goal. MRI >3 h accurately predicts infarction but is insensitive to selective neuronal loss (SNL). Previous studies suggest that chronic-stage (11)C-flumazenil PET (FMZ-PET) is a validated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3fadc18973e6fd0abff8d5076d429e2d
https://pubmed.ncbi.nlm.nih.gov/31637947
https://pubmed.ncbi.nlm.nih.gov/31637947
Autor:
David K. Menon, John S. Beech, Théotime Nadot, Franklin I. Aigbirhio, Tim D. Fryer, Jean-Claude Baron, Simon Jones, Jessica L Hughes, Dechao Wang
Publikováno v:
Stroke. 50
Background: Predicting ischemic brain damage early after stroke is an important goal. T2-Weighted MRI >3hrs after stroke onset accurately predicts infarction but is insensitive to selective neuronal loss (SNL). Chronic-stage 11 C-flumazenil PET (FMZ-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05c28f19c80b867f32030d2a935f5ce5
https://doi.org/10.1161/str.50.suppl_1.wmp84
https://doi.org/10.1161/str.50.suppl_1.wmp84
Autor:
Ben J. Slotman, Sally A. Hill, Kitty C. M. Castricum, Victor L. Thijssen, John S. Beech, Philip D. Allen, Adrian L. Harris, Ruth J. Muschel, Esther A. Kleibeuker, Iris A. Schulkens, Jaehong H. Im, Jaap van den Berg, Veerle Kersemans, Arjan W. Griffioen, Sean Smart, Henk M.W. Verheul, Emmanouil Fokas
Publikováno v:
Oncotarget
Oncotarget, 7(47), 76613-76627. Impact Journals
Kleibeuker, E A, Fokas, E, Allen, P D, Kersemans, V, Griffioen, A W, Beech, J, Im, J H, Smart, S C, Castricum, K C, van den Berg, J, Schulkens, I A, Hill, S A, Harris, A L, Slotman, B J, Verheul, H M, Muschel, R J & Thijssen, V L 2016, ' Low dose angiostatic treatment counteracts radiotherapy-induced tumor perfusion and enhances the anti-tumor effect ', Oncotarget, vol. 7, no. 47, pp. 76613-76627 . https://doi.org/10.18632/oncotarget.12814
Oncotarget, 7(47), 76613-76627. Impact Journals
Kleibeuker, E A, Fokas, E, Allen, P D, Kersemans, V, Griffioen, A W, Beech, J, Im, J H, Smart, S C, Castricum, K C, van den Berg, J, Schulkens, I A, Hill, S A, Harris, A L, Slotman, B J, Verheul, H M, Muschel, R J & Thijssen, V L 2016, ' Low dose angiostatic treatment counteracts radiotherapy-induced tumor perfusion and enhances the anti-tumor effect ', Oncotarget, vol. 7, no. 47, pp. 76613-76627 . https://doi.org/10.18632/oncotarget.12814
The extent of tumor oxygenation is an important factor contributing to the efficacy of radiation therapy (RTx). Interestingly, several preclinical studies have shown benefit of combining RTx with drugs that inhibit tumor blood vessel growth, i.e. ang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc1ae03b4209e5f1ea53dd2422e54c1
http://europepmc.org/articles/PMC5363534
http://europepmc.org/articles/PMC5363534