Zobrazeno 1 - 10
of 96
pro vyhledávání: '"John S, O'Neill"'
Autor:
Christine T Styles, Jie Zhou, Katie E Flight, Jonathan C Brown, Charlotte Lewis, Xinyu Wang, Michael Vanden Oever, Thomas P Peacock, Ziyin Wang, Rosie Millns, John S O'Neill, Alexander Borodavka, Joe Grove, Wendy S Barclay, John S Tregoning, Rachel S Edgar
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp 1-12 (2023)
Abstract Viruses are vulnerable as they transmit between hosts, and we aimed to exploit this critical window. We found that the ubiquitous, safe, inexpensive and biodegradable small molecule propylene glycol (PG) has robust virucidal activity. Propyl
Externí odkaz:
https://doaj.org/article/81c9583b032d41f389c366a3cc12589e
Autor:
Christine T Styles, Jie Zhou, Katie E Flight, Jonathan C Brown, Charlotte Lewis, Xinyu Wang, Michael Vanden Oever, Thomas P Peacock, Ziyin Wang, Rosie Millns, John S O’Neill, Alexander Borodavka, Joe Grove, Wendy S Barclay, John S Tregoning, Rachel S Edgar
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 7, Pp 1751-1751 (2024)
Externí odkaz:
https://doaj.org/article/f4a74545bc594cc4bcccd449114fd4d7
Autor:
Alessandra Stangherlin, Joseph L. Watson, David C. S. Wong, Silvia Barbiero, Aiwei Zeng, Estere Seinkmane, Sew Peak Chew, Andrew D. Beale, Edward A. Hayter, Alina Guna, Alison J. Inglis, Marrit Putker, Eline Bartolami, Stefan Matile, Nicolas Lequeux, Thomas Pons, Jason Day, Gerben van Ooijen, Rebecca M. Voorhees, David A. Bechtold, Emmanuel Derivery, Rachel S. Edgar, Peter Newham, John S. O’Neill
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Osmotic compensation by electroneutral ion transport buffers TORC1-mediated changes in the cytosolic proteome, and maintains intracellular homeostasis and cell volume over the circadian cycle. Here, the authors find such ion content changes drive dai
Externí odkaz:
https://doaj.org/article/d608bbcc713a4841b6211ae27b0bfe88
Autor:
Holly Kay, Ellen Grünewald, Helen K. Feord, Sergio Gil, Sew Y. Peak-Chew, Alessandra Stangherlin, John S. O’Neill, Gerben van Ooijen
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Holly Kay, Ellen Grünewald, et al. provide an in-depth examination of the proteome in the eukaryotic green alga, Ostreococcus tauri, under circadian constant light or cycling diurnal light-dark conditions. They observe that there is little overlap b
Externí odkaz:
https://doaj.org/article/5d1cd59dcc7e47d8a24083d7cbcd5956
Autor:
Martin R Ralph, Shu-Qun Shi, Carl H Johnson, Pavel Houdek, Tenjin C Shrestha, Priya Crosby, John S O'Neill, Martin Sládek, Adam R Stinchcombe, Alena Sumová
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 5, p e1008987 (2021)
Modification of the Per2 clock gene in mPer2Luc reporter mice significantly alters circadian function. Behavioral period in constant dark is lengthened, and dissociates into two distinct components in constant light. Rhythms exhibit increased bimodal
Externí odkaz:
https://doaj.org/article/e98516d1343e4612b43b371cca13078b
Autor:
John S. O’Neill, Nathaniel P. Hoyle, J. Brian Robertson, Rachel S. Edgar, Andrew D. Beale, Sew Y. Peak-Chew, Jason Day, Ana S. H. Costa, Christian Frezza, Helen C. Causton
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/3d8511efe6754e5abea861c8a3360cef
Autor:
Edward A. Hayter, Sophie M. T. Wehrens, Hans P. A. Van Dongen, Alessandra Stangherlin, Shobhan Gaddameedhi, Elena Crooks, Nichola J. Barron, Luigi A. Venetucci, John S. O’Neill, Timothy M. Brown, Debra J. Skene, Andrew W. Trafford, David A. Bechtold
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/af3e22bd3d8c486d8552720ff8489fea
Autor:
Erin A. Henslee, Priya Crosby, Stephen J. Kitcatt, Jack S. W. Parry, Andrea Bernardini, Rula G. Abdallat, Gabriella Braun, Henry O. Fatoyinbo, Esther J. Harrison, Rachel S. Edgar, Kai F. Hoettges, Akhilesh B. Reddy, Rita I. Jabr, Malcolm von Schantz, John S. O’Neill, Fatima H. Labeed
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Circadian rhythms usually rely on cyclic variations in gene expression. Red blood cells, however, display circadian rhythms while being devoid of nuclear DNA. Here, Henslee and colleagues show that circadian rhythms in isolated human red blood cells
Externí odkaz:
https://doaj.org/article/3b9cc98ebe9f4f4a828664161f701abc
Autor:
Alessandra Stangherlin, Joseph L. Watson, David C. S. Wong, Silvia Barbiero, Aiwei Zeng, Estere Seinkmane, Sew Peak Chew, Andrew D. Beale, Edward A. Hayter, Alina Guna, Alison J. Inglis, Marrit Putker, Eline Bartolami, Stefan Matile, Nicolas Lequeux, Thomas Pons, Jason Day, Gerben van Ooijen, Rebecca M. Voorhees, David A. Bechtold, Emmanuel Derivery, Rachel S. Edgar, Peter Newham, John S. O’Neill
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/ce8210b5c1134255b82aa740bd07ccb6
Autor:
David S Tourigny, Muhammad Kaiser Abdul Karim, Rodrigo Echeveste, Mark R N Kotter, John S O'Neill
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220937 (2019)
Neural networks are required to meet significant metabolic demands associated with performing sophisticated computational tasks in the brain. The necessity for efficient transmission of information imposes stringent constraints on the metabolic pathw
Externí odkaz:
https://doaj.org/article/1eef4aebdb9e4ddc9fbf7285f7e92475