Zobrazeno 1 - 10
of 349
pro vyhledávání: '"John S, Mattick"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Convolutional Neural Networks (CNNs) have been central to the Deep Learning revolution and played a key role in initiating the new age of Artificial Intelligence. However, in recent years newer architectures such as Transformers have dominat
Externí odkaz:
https://doaj.org/article/35d2510217d742bbbe6458a2591b8c37
Autor:
Pinki Dey, John S. Mattick
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-11 (2021)
Abstract Background It is established that protein-coding exons are preferentially localized in nucleosomes. To examine whether the same is true for non-coding exons, we analysed nucleosome occupancy in and adjacent to internal exons in genes encodin
Externí odkaz:
https://doaj.org/article/4f387b11f5b34b3f811fb13bf6c1b81e
Autor:
Wei Wei, Qiongyi Zhao, Ziqi Wang, Wei-Siang Liau, Dean Basic, Haobin Ren, Paul R. Marshall, Esmi L. Zajaczkowski, Laura J. Leighton, Sachithrani U. Madugalle, Mason Musgrove, Ambika Periyakaruppiah, Jichun Shi, Jianjian Zhang, John S. Mattick, Timothy R. Mercer, Robert C. Spitale, Xiang Li, Timothy W. Bredy
Publikováno v:
Cell Reports, Vol 38, Iss 12, Pp 110546- (2022)
Summary: Here, we used RNA capture-seq to identify a large population of lncRNAs that are expressed in the infralimbic prefrontal cortex of adult male mice in response to fear-related learning. Combining these data with cell-type-specific ATAC-seq on
Externí odkaz:
https://doaj.org/article/780e722429aa497c8ef62de662ee166e
Integrative analyses of the RNA modification machinery reveal tissue- and cancer-specific signatures
Autor:
Oguzhan Begik, Morghan C. Lucas, Huanle Liu, Jose Miguel Ramirez, John S. Mattick, Eva Maria Novoa
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-24 (2020)
Abstract Background RNA modifications play central roles in cellular fate and differentiation. However, the machinery responsible for placing, removing, and recognizing more than 170 RNA modifications remains largely uncharacterized and poorly annota
Externí odkaz:
https://doaj.org/article/090b5c5c4b8f45c9bf055906b7e847bc
Autor:
Huanle Liu, Oguzhan Begik, Morghan C. Lucas, Jose Miguel Ramirez, Christopher E. Mason, David Wiener, Schraga Schwartz, John S. Mattick, Martin A. Smith, Eva Maria Novoa
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
We currently lack generic methods to map RNA modifications across the entire transcriptome. Here, the authors demonstrate that m6A RNA modifications can be detected with high accuracy using nanopore direct RNA sequencing.
Externí odkaz:
https://doaj.org/article/9b36004b41f44913a89a8cca26a8ff72
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-12 (2017)
Abstract The diversity of processed transcripts in eukaryotic genomes poses a challenge for the classification of their biological functions. Sparse sequence conservation in non-coding sequences and the unreliable nature of RNA structure predictions
Externí odkaz:
https://doaj.org/article/b281f17b880e4f49b47f10f51b22fe73
Autor:
Gareth Baynam, Stephanie Broley, Alicia Bauskis, Nicholas Pachter, Fiona McKenzie, Sharron Townshend, Jennie Slee, Cathy Kiraly-Borri, Anand Vasudevan, Anne Hawkins, Lyn Schofield, Petra Helmholz, Richard Palmer, Stefanie Kung, Caroline E. Walker, Caron Molster, Barry Lewis, Kym Mina, John Beilby, Gargi Pathak, Cathryn Poulton, Tudor Groza, Andreas Zankl, Tony Roscioli, Marcel E. Dinger, John S. Mattick, William Gahl, Stephen Groft, Cynthia Tifft, Domenica Taruscio, Paul Lasko, Kenjiro Kosaki, Helene Wilhelm, Bela Melegh, Jonathan Carapetis, Sayanta Jana, Gervase Chaney, Allison Johns, Peter Wynn Owen, Frank Daly, Tarun Weeramanthri, Hugh Dawkins, Jack Goldblatt
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 12, Iss 1, Pp 1-8 (2017)
Abstract Background New approaches are required to address the needs of complex undiagnosed diseases patients. These approaches include clinical genomic diagnostic pipelines, utilizing intra- and multi-disciplinary platforms, as well as specialty-spe
Externí odkaz:
https://doaj.org/article/fd1d44fbca064efaae5bfc0d962bda6b
Autor:
Nenad Bartonicek, Romain Rouet, Joanna Warren, Claudia Loetsch, Gabriela Santos Rodriguez, Stacey Walters, Francis Lin, David Zahra, James Blackburn, Jillian M. Hammond, Andre L. M. Reis, Ira W. Deveson, Nathan Zammit, Mahdi Zeraati, Shane Grey, Daniel Christ, John S. Mattick, Tatyana Chtanova, Robert Brink, Marcel E. Dinger, Robert J. Weatheritt, Jonathan Sprent, Cecile King
Publikováno v:
Nature. 608:757-765
The notion that mobile units of nucleic acid known as transposable elements can operate as genomic controlling elements was put forward over six decades ago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27129ac28c9e0128f0cec7bb7be80b49
https://doi.org/10.1038/s41586-022-05054-9
https://doi.org/10.1038/s41586-022-05054-9
Autor:
Simon A. Hardwick, Samuel D. Bassett, Dominik Kaczorowski, James Blackburn, Kirston Barton, Nenad Bartonicek, Shaun L. Carswell, Hagen U. Tilgner, Clement Loy, Glenda Halliday, Tim R. Mercer, Martin A. Smith, John S. Mattick
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
The human brain is one of the last frontiers of biomedical research. Genome-wide association studies (GWAS) have succeeded in identifying thousands of haplotype blocks associated with a range of neuropsychiatric traits, including disorders such as sc
Externí odkaz:
https://doaj.org/article/1e92fdf57727448c8d717531c35b6024
Autor:
Ranjan J. Perera, John S. Mattick, Martin A. Smith, Joanna Crawford, Joseph Mazar, Marcel E. Dinger, Divya Khaitan
Supplementary Video 1 from The Melanoma‐Upregulated Long Noncoding RNA SPRY4-IT1 Modulates Apoptosis and Invasion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813d3bc9bf46042ad5fa818fb89d9114
https://doi.org/10.1158/0008-5472.22395936.v1
https://doi.org/10.1158/0008-5472.22395936.v1
