Zobrazeno 1 - 10
of 197
pro vyhledávání: '"John R. Williamson"'
Publikováno v:
Acta Medica Scandinavica. 199:95-112
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98c7bb800b93d88753f316c26bbfc855
https://doi.org/10.1111/j.0954-6820.1976.tb05871.x
https://doi.org/10.1111/j.0954-6820.1976.tb05871.x
Publikováno v:
Journal of Cellular Biochemistry. 82:556-565
p38 MAP kinases (p38) and c-Jun N-terminal protein kinases (JNK) have been associated with TNF-α-induced apoptosis. However, recent studies indicate that an early but brief activation of JNK and/or p38 may actually protect some cells from TNF-α-ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55a8d617762179014b2fd6af0861e63a
https://doi.org/10.1002/jcb.1180
https://doi.org/10.1002/jcb.1180
Publikováno v:
American Journal of Physiology-Cell Physiology. 276:C435-C441
We reported previously that Ro-318220 blocked expression of mitogen-activated protein kinase phosphatase-1 (MKP-1) induced by tumor necrosis factor-α (TNF-α) and subsequently caused apopotosis in mesangial cells (Y.-L. Guo, B. Kang, and J. R. Willi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a169da6e3b457785ec1ba998c26276a
https://doi.org/10.1152/ajpcell.1999.276.2.c435
https://doi.org/10.1152/ajpcell.1999.276.2.c435
Publikováno v:
Journal of Biological Chemistry. 273:10362-10366
Previously we showed that rat mesangial cells are normally resistant to tumor necrosis factor-alpha (TNF-alpha)-induced apoptosis. They are made susceptible to the apoptotic effect of TNF-alpha when pretreated with actinomycin D, cycloheximide or van
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7481879f4d84c4ba80ebe3d73940c22
https://doi.org/10.1074/jbc.273.17.10362
https://doi.org/10.1074/jbc.273.17.10362
Autor:
Quiyang Li, Lijun Yang, Judith A. Maloney, Agnieszka Szot, Oxana M. Tsygankova, John R. Williamson
Publikováno v:
American Journal of Physiology-Cell Physiology. 274:C974-C982
The protein kinase C (PKC) family represents an important group of enzymes whose activation is associated with their translocation from the cytosol to different cellular membranes. In this study, the spatial distribution of PKC-alpha, -delta and -eps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea1516aaccd01c26f8dd80aebe4ed72
https://doi.org/10.1152/ajpcell.1998.274.4.c974
https://doi.org/10.1152/ajpcell.1998.274.4.c974
Publikováno v:
Journal of Cellular Biochemistry. 69:63-71
Angiotensin II stimulates a biphasic activation of Raf-1, MEK, and ERK in WB liver epithelial cells. The first peak of activity is rapid and transient and is followed by a sustained phase. Angiotensin II also causes a rapid activation of p21ras in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b84ea48cc4071e3c31001b452683920
https://doi.org/10.1002/(sici)1097-4644(19980401)69:1<63::aid-jcb7>3.0.co
https://doi.org/10.1002/(sici)1097-4644(19980401)69:1<63::aid-jcb7>3.0.co
Publikováno v:
Biochemical and Biophysical Research Communications. 228:802-806
Association of phospholipase C (PLC)-gamma 1 with the cytoskeleton has been postulated to be one of the crucial steps for PLC-gamma 1 activation and translocation to the plasma membrane. In this report, direct binding assays were carried out to study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69e9c0820b04777a45346332215c84c
https://doi.org/10.1006/bbrc.1996.1735
https://doi.org/10.1006/bbrc.1996.1735
Publikováno v:
Journal of Biological Chemistry. 269:7156-7162
In this study, we have examined the relationship between epidermal growth factor (EGF)-induced tyrosine phosphorylation of phospholipase C-gamma 1 (PLC-gamma 1) and its translocation from the cytosol to the Triton X-100-insoluble cytoskeleton fractio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::218d646c15eb55b7f5eac5d9f6abbabe
https://doi.org/10.1016/s0021-9258(17)37261-7
https://doi.org/10.1016/s0021-9258(17)37261-7
Publikováno v:
Diabetes. 42:1878-1882
Fuel- and receptor-induced signal transduction pathways were investigated in beta-TC3 cells, an insulin-secreting cell line. An increase of glucose concentration from 0 to 15 mM and stimulation with 0.5 mM carbachol resulted in up to a twofold increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f22ab2b663613873f56e43ad53cd88
https://doi.org/10.2337/diab.42.12.1878
https://doi.org/10.2337/diab.42.12.1878
Publikováno v:
Journal of Biological Chemistry. 268:6511-6519
The regulation of intracellular pools of Ca2+ was investigated in an interleukin-3 (IL-3)-dependent hematopoietic cell line 32D that undergoes programmed cell death ("apoptosis") when deprived of lymphokine. Comparisons were made with 32D cells that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec20cb5f0708d8780c9e1d16e4ed99b9
https://doi.org/10.1016/s0021-9258(18)53280-4
https://doi.org/10.1016/s0021-9258(18)53280-4