Zobrazeno 1 - 10
of 114
pro vyhledávání: '"John R. Webb"'
Autor:
Natasha Kekre, Kevin A. Hay, John R. Webb, Ranjeeta Mallick, Miruna Balasundaram, Mhairi K. Sigrist, Anne-Marie Clement, Julie S. Nielsen, Jennifer Quizi, Eric Yung, Scott D. Brown, Lisa Dreolini, Daniel D. Waller, Julian Smazynski, Nicole S. Gierc, Bianca C. Loveless, Kayla Clark, Tyler Dyer, Richard Hogg, Leah McCormick, Michael Gignac, Shanti Bell, D. Maria Chapman, David Bond, Siao Yong, Rachel Fung, Heather M. Lockyer, Victoria Hodgson, Catherine Murphy, Ana Subramanian, Evelyn Wiebe, Piriya Yoganathan, Liana Medynski, Dominique C. Vaillan, Alice Black, Sheryl McDiarmid, Michael Kennah, Linda Hamelin, Kevin Song, Sujaatha Narayanan, Judith A. Rodrigo, Stefany Dupont, Terry Hawrysh, Justin Presseau, Kednapa Thavorn, Manoj M. Lalu, Dean A. Fergusson, John C. Bell, Harold Atkins, Brad H. Nelson, Robert A. Holt
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Access to commercial CD19 CAR-T cells remains limited even in wealthy countries like Canada due to clinical, logistical, and financial barriers related to centrally manufactured products. We created a non-commercial academic platform for end-to-end m
Externí odkaz:
https://doaj.org/article/ba9bb5ccb69a4646aee78f29aa8e0137
Autor:
Lisa Dreolini, Mark Cullen, Eric Yung, Lawrence Laird, John R. Webb, Brad H. Nelson, Kevin A. Hay, Miruna Balasundaram, Natasha Kekre, Robert A. Holt
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 393-399 (2020)
Mycoplasma species (spp.) bacteria can infect cell cultures, posing a potential threat to recipients of cell therapy products. Conventional Mycoplasma testing methods are highly sensitive but typically require a minimum of 28 days to produce results.
Externí odkaz:
https://doaj.org/article/999a6fbd36cd41d6b988f524b73f3d75
Autor:
Julian Smazynski, John R. Webb
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Resident memory T cells (TRM) are a recently identified subset of long-lived memory T cells that are characterized in terms of their unique surface phenotype combined with a non-recirculating pattern of localization to non-lymphoid, peripheral tissue
Externí odkaz:
https://doaj.org/article/2c443e654b6145f989245210c6d772ae
Autor:
Julie S. Nielsen, Andrew R. Chang, Darin A. Wick, Colin G. Sedgwick, Zusheng Zong, Andrew J. Mungall, Spencer D. Martin, Natalie N. Kinloch, Susann Ott-Langer, Zabrina L. Brumme, Steven P. Treon, Joseph M. Connors, Randy D. Gascoyne, John R. Webb, Brian R. Berry, Ryan D. Morin, Nicol Macpherson, Brad H. Nelson
Publikováno v:
OncoImmunology, Vol 6, Iss 7 (2017)
Oncogenic “driver” mutations are theoretically attractive targets for the immunotherapy of lymphoid cancers, yet the proportion that can be recognized by T cells remains poorly defined. To address this issue without any confounding effects of the
Externí odkaz:
https://doaj.org/article/fb3d07d87ea0480292f902b4900879f2
Autor:
Brad H. Nelson, Christian Steidl, John R. Webb, Katy Milne, Shelby Thornton, Lauren C. Chong, Elizabeth A. Chavez, Nicole S. Gierc, Julian Smazynski, Maartje C.A. Wouters, Céline M. Laumont
Supplementary Figure S14 shows the extent of TCR overlap between T-cell subsets isolated from primary HGSC tumor samples.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34cf426db4e212ba09e3a6803100ce42
https://doi.org/10.1158/1078-0432.22480818.v1
https://doi.org/10.1158/1078-0432.22480818.v1
Purpose: CD103 is expressed in several immune cell types but in the context of the intratumoral immune response may be most important as a marker of antigen-activated CD8 T cells.Methods: We have examined the prognostic significance of CD103 TILs in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7111b091fe44bc00a88ce5a32aaa57da
https://doi.org/10.1158/1078-0432.c.6526716
https://doi.org/10.1158/1078-0432.c.6526716
Supplemental Table 1. A report concerning the source of the biospecimen and data using the BRISQ guidelines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1048b02fe838e415c524a3720f29ae8
https://doi.org/10.1158/1078-0432.22467699
https://doi.org/10.1158/1078-0432.22467699
Autor:
Brad H. Nelson, Rob A. Holt, Peter H. Watson, Kwame Twumasi-Boateng, Mauro Castellarin, Katy Milne, David R. Kroeger, Spencer D. Martin, Julie S. Nielsen, John R. Webb, Darin A. Wick
Purpose: Cancers accumulate mutations over time, each of which brings the potential for recognition by the immune system. We evaluated T-cell recognition of the tumor mutanome in patients with ovarian cancer undergoing standard treatment.Experimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ad806360bdb11a8d0aa7fb33957838
https://doi.org/10.1158/1078-0432.c.6521546
https://doi.org/10.1158/1078-0432.c.6521546
Autor:
Brad H. Nelson, Christian Steidl, John R. Webb, Katy Milne, Shelby Thornton, Lauren C. Chong, Elizabeth A. Chavez, Nicole S. Gierc, Julian Smazynski, Maartje C.A. Wouters, Céline M. Laumont
Supplementary Table S4 presents the list of differentially expressed genes identified between triple-positive and triple-negative Tregs and between triple-positive and other Tregs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::201408ad5046aeece798096513de96c1
https://doi.org/10.1158/1078-0432.22480770.v1
https://doi.org/10.1158/1078-0432.22480770.v1
Supplemental Figure 2: Prognostic impact of CD103 and CD8 alone and combination in the Basel-like subset of breast cancers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e123fe30899a07f8d3cbb8c18ddbb591
https://doi.org/10.1158/1078-0432.22467702.v1
https://doi.org/10.1158/1078-0432.22467702.v1