Zobrazeno 1 - 10
of 27
pro vyhledávání: '"John R. Underwood"'
Autor:
John R. Underwood, Paul V. Licciardi
Publikováno v:
International Immunopharmacology. 11:390-398
Plant-derived medicines have a long history of use for the prevention and treatment of human disease. Today, many pharmaceuticals currently approved by the Food and Drug Administration (FDA) have origins to plant sources. A major role for plant-deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ef18683633bf07bb1e47a9f17e3c5d
https://doi.org/10.1016/j.intimp.2010.10.014
https://doi.org/10.1016/j.intimp.2010.10.014
Autor:
Michael E. Lilly, Philip J. Carr, John R. Underwood, William L. Kingery, Evan Peacock, Sarah E. Price
Publikováno v:
Southeastern Archaeology. 29:355-368
Site 22LI504 is a predominantly Archaic period site in Lincoln County, Mississippi. One of its primary elements of interest is a single conical mound from which small-diameter cores revealed evidence of advanced pedogenesis. A radiocarbon sample from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e677837e6121b95f40f811b2a3212eff
https://doi.org/10.1179/sea.2010.29.2.010
https://doi.org/10.1179/sea.2010.29.2.010
Autor:
John R. Underwood, Paul V. Licciardi
Publikováno v:
Vaccine. 28:3865-3873
Immunomodulation by plant-derived medicines is well-documented with effects on both innate and adaptive immunity. This study reports potent and long-lasting diphtheria toxoid-specific immunity by the botanical medicinal, Rehmannia Six Formula, using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7994d37c1bf120972a2430d211ca137
https://doi.org/10.1016/j.vaccine.2010.02.073
https://doi.org/10.1016/j.vaccine.2010.02.073
Autor:
Magda Kvasnicka, Marcus W. Brazier, Andrew F. Hill, Irene Volitakis, Anthony R. White, Steven J. Collins, Sen Han, Colin L. Masters, John R. Underwood, Jason E. Green
Publikováno v:
Journal of Neurochemistry. 114:440-451
Previous in vitro and in vivo investigations have suggested manganese (Mn(2+)) may play a role in pathogenesis through facilitating refolding of the normal cellular form of the prion protein into protease resistant, pathogenic isoforms (PrP(Sc)), as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45f7fa68c611ec6026a2a932d6d16243
https://doi.org/10.1111/j.1471-4159.2010.06771.x
https://doi.org/10.1111/j.1471-4159.2010.06771.x
Autor:
Antony Bacic, Steven Binos, Prithi S. Bhathal, John R. Underwood, Simon G. Royce, David Oxley
Publikováno v:
Hybridoma. 29:84-101
Autoantibodies to gastric cellular antigens and glycoproteins including mucins and Lewis X and Y antigens have been implicated in the induction of autoimmune gastritis. Monoclonal antibody D10 (D10 MAb) recognizes a highly conserved mucin expressed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42196859a998c13e0fd1ff4d7e97a4dc
https://doi.org/10.1089/hyb.2009.0093
https://doi.org/10.1089/hyb.2009.0093
Publikováno v:
Vaccine. 27:6634-6641
The immunomodulatory properties of botanical medicinals are well-documented. In this study, the capacity for the traditional Chinese herbal medicine, Rehmannia Six Formula (R6F), to stimulate anti-tetanus toxoid (TT) immunity following oral administr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22738e13bcbbaccc693e9a99afec74fd
https://doi.org/10.1016/j.vaccine.2009.03.051
https://doi.org/10.1016/j.vaccine.2009.03.051
Autor:
C.L. Masters, Peter J. Hudson, S. Fuller, Roberto Cappai, A. H. Tammer, G. Coia, John R. Underwood
Publikováno v:
Clinical and Experimental Immunology. 129:453-463
SUMMARY A recombinant Fab antibody, designated 1E8–4b, which reacts with the Alzheimer's disease (AD)-related Aβ peptides, Aβ[1–40], Aβ[1–42] and Aβ[1–43] has been developed. The 1E8–4b Fab was constructed by cloning the VHCH1 and VLCL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::889fe0d5d4d5f5eb9ea73a629accfb16
https://doi.org/10.1046/j.1365-2249.2002.01905.x
https://doi.org/10.1046/j.1365-2249.2002.01905.x
Autor:
H. Wadsworth, David Allsop, R. Markwell, Robin V. Ward, Colin L. Masters, Eric Karran, Konrad Beyreuther, Roberto Cappai, Gary Christie, L. Smith, S. K. Gribble, Tobias Hartmann, A. Tamaoka, R. L. Gardner, D. R. Howlett, F. Mansfield, F. Godfrey, Michael R. McLaughlin, Rodney A. King, A. J. Rivett, D. G. Cooper, Carol W. Gray, Stefan F. Lichtenthaler, John R. Underwood
Publikováno v:
Journal of Neurochemistry. 73:195-204
Peptide aldehyde inhibitors of the chymotrypsin-like activity of the proteasome (CLIP) such as N-acetyl-Leu-Leu-Nle-H (or ALLN) have been shown previously to inhibit the secretion of beta-amyloid peptide (A beta) from cells. To evaluate more fully th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a059f99e7241d7b4b35bc84c054f824
https://doi.org/10.1046/j.1471-4159.1999.0730195.x
https://doi.org/10.1046/j.1471-4159.1999.0730195.x
Autor:
U. L. H. R. Jayasena, C.L. Masters, A. Mckenzie, S. K. Gribble, John R. Underwood, Konrad Beyreuther
Publikováno v:
Clinical and Experimental Immunology. 124:297-305
The accumulation of amyloid plaques and amyloid congophilic angiopathy (ACA) in the brains of affected individuals is one of the main pathological features of Alzheimer's disease. Within these deposits, the beta A4 (Ass) polypeptide represents a majo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf81269ef79b632937c4aa797913221
https://doi.org/10.1046/j.1365-2249.2001.01209.x
https://doi.org/10.1046/j.1365-2249.2001.01209.x
Autor:
C Gray, J.E. Tanner, John R. Underwood, Denise Galatis, Konrad Beyreuther, Genevieve Evin, S. Holmes, Roberto Cappai, D. Le Brocque, Colin L. Masters, Qiao-Xin Li, Anna Henry
Publikováno v:
Biochemistry. 37:14958-14965
betaA4 (Abeta) amyloid peptide, a major component of Alzheimer's disease (AD) plaques, is a proteolytic product of the amyloid precursor protein (APP). Endoproteases, termed beta- and gamma-secretase, release respectively the N- and C-termini of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c08c15b6dd142c247f3e6eb78e84eb
https://doi.org/10.1021/bi981063l
https://doi.org/10.1021/bi981063l