Zobrazeno 1 - 5
of 5
pro vyhledávání: '"John R. Torricelli"'
Autor:
Gregory J. Brewer, John R. Torricelli
Publikováno v:
Nature Protocols. 2:1490-1498
Here we present a protocol for extraction and culture of neurons from adult rat or mouse CNS. The method proscribes an optimized protease digestion of slices, control of osmolarity and pH outside the incubator with Hibernate and density gradient sepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4942ef8305733bdb44dc5002443502a9
https://doi.org/10.1038/nprot.2007.207
https://doi.org/10.1038/nprot.2007.207
Publikováno v:
Experimental Gerontology. 40:426-437
Neuronal degeneration increases with age in response to stressors, but the sub-cellular mechanism is unknown, partly because of previous difficulty in studying aged neurons in isolation. We studied the mechanism of enhanced neuronal susceptibility to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806434e838bed6d5bb48458b7554ce2d
https://doi.org/10.1016/j.exger.2005.03.007
https://doi.org/10.1016/j.exger.2005.03.007
Publikováno v:
Journal of Neuroscience Research. 35:567-576
We have systematically optimized the concentrations of 20 components of a previously published serum-free medium (Brewer and Cotman, Brain Res 494: 65-74, 1989) for survival of rat embryonic hippocampal neurons after 4 days in culture. This serum-fre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1816c1aceffe5fe89506cd8359f0829
https://doi.org/10.1002/jnr.490350513
https://doi.org/10.1002/jnr.490350513
Autor:
James A. Joseph, Elizabeth Z. Kunz, A. Neuman, Derek R. Fisher, John R. Torricelli, Gregory J. Brewer, Amanda L. Lindsey
Further clarification is needed to address the paradox that memory formation, aging and neurodegeneration all involve calcium influx, oxyradical production (ROS) and activation of certain signaling pathways. In aged rats and in APP/PS-1 mice, cogniti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1489fc31e2636163dcaca378625d96b
https://europepmc.org/articles/PMC2891857/
https://europepmc.org/articles/PMC2891857/
Autor:
Mordhwaj S. Parihar, Gregory J. Brewer, Elizabeth A. Kunz, Frank M. LaFerla, John R. Torricelli, Salvador S. Oddo
Publikováno v:
Alzheimer's & Dementia. 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f81622c96620e889133650750ec270f6
https://doi.org/10.1016/j.jalz.2008.05.2232
https://doi.org/10.1016/j.jalz.2008.05.2232