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pro vyhledávání: '"John R. Strikwerda"'
Autor:
John R Strikwerda, Steven M Sine
Publikováno v:
eLife, Vol 10 (2021)
Whether ion channel gating is independent of ion permeation has been an enduring, unresolved question. Here, applying single channel recording to the archetypal muscle nicotinic receptor, we unmask coupling between channel gating and ion permeation b
Externí odkaz:
https://doaj.org/article/648ebdb8c8b64fa29fc79ccf1b83a224
Publikováno v:
Biophysical Journal.
Publikováno v:
British journal of pharmacologyREFERENCES. 179(7)
BACKGROUND AND PURPOSE α4β2 nicotinic acetylcholine receptors (nAChRs) comprise the most abundant class of nAChRs in the nervous system. They assemble in two stoichiometric forms, each exhibiting distinct functional and pharmacological signatures.
Publikováno v:
Neuropharmacology
The ten types of nicotinic acetylcholine receptor α-subunits show substantial sequence homology, yet some types confer high affinity for α-bungarotoxin, whereas others confer negligible affinity. Combining sequence alignments with structural data r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50d47d7149fc0265bb5785654573c06
https://europepmc.org/articles/PMC6842095/
https://europepmc.org/articles/PMC6842095/
Publikováno v:
Chemical Physics Letters. 547:120-126
We employ the Slater–Zener model to relate effective atomic radius to ionization energy: r e = na 0 I H / I ¯ v ; n is the principal quantum number of the valence shell, a0 is the Bohr radius, IH is the ionization energy of the hydrogen atom, and
Publikováno v:
Theoretical Chemistry Accounts. 130:871-881
We have performed theoretical studies on sixteen molecular cubes for both (NH3·HCl)(H2O)6 and (NH3·HF)(H2O)6. We use an empirical gauge, based upon the N–H and H–X bond lengths, to categorize the degree to which the cubes are neutral adduct or
Autor:
Roger L. DeKock, John R. Strikwerda
Publikováno v:
Journal of Chemical Education. 89:569-569
We argue that localized bond orbitals can be used to interpret photoelectron spectra of molecules.