Zobrazeno 1 - 10
of 229
pro vyhledávání: '"John R. Roth"'
Publikováno v:
Genetics, vol 214, iss 2
In the Cairns-Foster adaptive mutation system, lac mutant cells are plated on lactose medium where 50 revertant colonies accumulate over 5 days above a non-growing lawn. A new model attributes this behavior to selective... The Escherichia coli system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef290102bcb0888648c43959edfc402
https://doi.org/10.1534/genetics.119.302754
https://doi.org/10.1534/genetics.119.302754
Autor:
John R. Roth, Kelly T. Hughes, Jordan J. Hendriksen, Christopher E. Wozniak, Baldomero M. Olivera
Publikováno v:
Journal of bacteriology, vol 202, iss 20
J Bacteriol
J Bacteriol
A mutant of Salmonella enterica serovar Typhimurium was isolated that simultaneously affected two metabolic pathways as follows: NAD metabolism and DNA repair. The mutant was isolated as resistant to a nicotinamide analog and as temperature-sensitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3525651ef9cd29a584374ce7d8cb78bf
https://escholarship.org/uc/item/0qx6w7kx
https://escholarship.org/uc/item/0qx6w7kx
Autor:
John R. Roth, Sophie Maisnier-Patin
Publikováno v:
Genetics, vol 210, iss 3
In the Cairns–Foster adaptive mutation system, a +1 lac frameshift mutant of Escherichia coli is plated on lactose medium, where the nondividing population gives rise to Lac+ revertant colonies during a week under selection. Reversion requires the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4539a771a5c5b9d0bdd49671f11e4d1
https://doi.org/10.1534/genetics.118.301347
https://doi.org/10.1534/genetics.118.301347
Publikováno v:
Genetics. 205:577-588
While most missense suppressors have very narrow specificities and only suppress the allele against which they were isolated, the sumA missense suppressor from Salmonella enterica serovar Typhimurium is a promiscuous or broad-acting missense suppress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1afb7e8e8af83761edcc9a79940a0a54
https://doi.org/10.1534/genetics.116.196550
https://doi.org/10.1534/genetics.116.196550
Publikováno v:
Genetics
The Escherichia coli system of Cairns and Foster employs a lac frameshift mutation that reverts rarely (10(−9)/cell/division) during unrestricted growth. However, when 10(8) cells are plated on lactose medium, the nongrowing lawn produces ∼50 Lac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0f960f6ebda0d0c43ffe9e458b62e1ae
https://pubmed.ncbi.nlm.nih.gov/31810989
https://pubmed.ncbi.nlm.nih.gov/31810989
Autor:
Sophie, Maisnier-Patin, John R, Roth
Publikováno v:
Genetics. 210(3)
In the Cairns–Foster adaptive mutation system, a +1 lac frameshift mutant of Escherichia coli is plated on lactose medium, where the nondividing population gives rise to Lac(+) revertant colonies during a week under selection. Reversion requires th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::997e0f656f5014dae146806ee41d27a6
https://pubmed.ncbi.nlm.nih.gov/30194073
https://pubmed.ncbi.nlm.nih.gov/30194073
Publikováno v:
Genetics, vol 208, iss 3
To test whether growth limitation induces mutations, Cairns and Foster constructed an Escherichia coli strain whose mutant lac allele provides 1–2% of normal ability to use lactose. This strain cannot grow on lactose, but produces ∼50 Lac+ revert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1cf882a5a8a3fd7f6d6ca4584a9e3a
https://escholarship.org/uc/item/7sv1f28m
https://escholarship.org/uc/item/7sv1f28m
Autor:
John R. Roth, Sophie Maisnier-Patin
Publikováno v:
Journal of bacteriology, vol 198, iss 7
Van Hofwegen et al. demonstrated that Escherichia coli rapidly evolves the ability to use citrate when long selective periods are provided (D. J. Van Hofwegen, C. J. Hovde, and S. A. Minnich, J Bacteriol 198:1022–1034, 2016, http://dx.doi.org/10.11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3db7b47e24d8569262ae48dcd4c578b
https://escholarship.org/uc/item/12f9m5dd
https://escholarship.org/uc/item/12f9m5dd
Autor:
John R. Roth, Sophie Maisnier-Patin
Selection and mutation are central contributors to evolutionary change. Mutation produces genetic variability upon which selection acts. The process of natural selection depends on the formation rate of multiple mutation types with different phenotyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e79477e6d4805274203e7f14b7038a5
https://doi.org/10.1016/b978-0-12-800049-6.00229-8
https://doi.org/10.1016/b978-0-12-800049-6.00229-8
Publikováno v:
Genetics. 192:397-415
Duplications are often attributed to “unequal recombination” between separated, directly repeated sequence elements (>100 bp), events that leave a recombinant element at the duplication junction. However, in the bacterial chromosome, duplications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b1dd41eb51c0d19525809a48de8d81
https://doi.org/10.1534/genetics.112.142570
https://doi.org/10.1534/genetics.112.142570