Zobrazeno 1 - 10
of 18
pro vyhledávání: '"John R. Montford"'
Autor:
John R. Montford, Allison M.B. Lehman, Colin D. Bauer, Jelena Klawitter, Jost Klawitter, Joanna M. Poczobutt, Micah Scobey, Mary Weiser-Evans, Raphael A. Nemenoff, Seth B. Furgeson
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 2, Pp 380-390 (2018)
The group IVA calcium-dependent cytosolic phospholipase A2 (cPLA2α) enzyme directs a complex “eicosanoid storm” that accompanies the tissue response to injury. cPLA2α and its downstream eicosanoid mediators are also implicated in the pathogenes
Externí odkaz:
https://doaj.org/article/3b8f94ee4d0040ea8bd38c602ae9ab62
Autor:
Brianna M. Liberio, Gregory Seedorf, Danielle E. Soranno, John R. Montford, Sarah G. Faubel, Andres Hernandez, Steven H. Abman, Jason Gien
Publikováno v:
Pediatric Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f5280d7f91e6a7812c84c2b012b12ff
https://doi.org/10.1038/s41390-023-02625-y
https://doi.org/10.1038/s41390-023-02625-y
IntroductionInfection is a leading cause of morbidity and mortality in individuals with kidney disease. Both acute kidney injury (AKI), and chronic kidney disease (CKD) are clinical states that have been associated with higher risk of incident infect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::947605c52f8dfc0f18a01ace88541394
https://doi.org/10.1101/2023.03.01.529424
https://doi.org/10.1101/2023.03.01.529424
Autor:
Danielle E. Soranno, Brysen Keith, DO Katja M. Gist, Kathy Ding, Rushita A. Bagchi, Timothy A. McKinsey, BS Sara A. Wennersten, John R. Montford, BS Lara Kirkbride-Romeo, BA Christopher Altmann, Korey R. Haefner, Sarah Faubel, Peter R. Baker, Maria A. Cavasin, Christian Steinkühler
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • This is the first long-term (1-year) study to evaluate both the kidney and systemic sequelae of acute kidney injury in mice. • Serial kidney function was measured via transcutaneous glomerular filtration rate.
Highlights • This is the first long-term (1-year) study to evaluate both the kidney and systemic sequelae of acute kidney injury in mice. • Serial kidney function was measured via transcutaneous glomerular filtration rate.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::121b9fb5514aec24384a2bd3606e83fc
http://europepmc.org/articles/PMC7907538
http://europepmc.org/articles/PMC7907538
Autor:
John R. Montford, Colin Bauer, Jeremy Rahkola, Julie A. Reisz, Deanna Floyd, Katharina Hopp, Danielle E. Soranno, Jelena Klawitter, Mary C. M. Weiser-Evans, Raphael Nemenoff, Sarah Faubel, Seth B. Furgeson
Publikováno v:
Am J Physiol Renal Physiol
15-Lipoxygenase (15-LO) is a nonheme iron-containing dioxygenase that has both pro- and anti-inflammatory roles in many tissues and disease states. 15-LO is thought to influence macrophage phenotype, and silencing 15-LO reduces fibrosis after acute i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2684bc07753ebf6b2e4d50bb7603b4e
https://pubmed.ncbi.nlm.nih.gov/34866403
https://pubmed.ncbi.nlm.nih.gov/34866403
Autor:
Lara A. Kirkbride-Romeo, Danielle E. Soranno, Hyo-Wook Gil, Sarah Faubel, Christopher Altmann, John R. Montford, Jane Buchanan, Ani Levine, Haichun Yang
Publikováno v:
J Am Soc Nephrol
Background The duration of renal ischemia that is associated with (or leads to) renal injury in patients is uncertain, and a reverse translational research approach has been proposed to improve animal models of AKI to facilitate clinical translatabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff5df1dd9e7781409eab6b6e24d43dbb
https://doi.org/10.1681/asn.2018080808
https://doi.org/10.1681/asn.2018080808
Autor:
Joanna M. Poczobutt, Seth B. Furgeson, Allison M.B. Lehman, John R. Montford, Micah S. Scobey, Jost Klawitter, Jelena Klawitter, Raphael A. Nemenoff, Colin D. Bauer, Mary C.M. Weiser-Evans
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 2, Pp 380-390 (2018)
The group IVA calcium-dependent cytosolic phospholipase A2 (cPLA2α) enzyme directs a complex “eicosanoid storm” that accompanies the tissue response to injury. cPLA2α and its downstream eicosanoid mediators are also implicated in the pathogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d225c5e9c91c293045d979c3dd9ac0c
http://www.sciencedirect.com/science/article/pii/S0022227520342401
http://www.sciencedirect.com/science/article/pii/S0022227520342401
Autor:
Stuart L. Linas, John R. Montford
Publikováno v:
Journal of the American Society of Nephrology. 28:3155-3165
Hyperkalemia is a potentially life-threatening electrolyte disorder appreciated with greater frequency in patients with renal disease, heart failure, and with use of certain medications such as renin angiotensin aldosterone inhibitors. The traditiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca183d6e5666fe90fda6e84c71e6805f
https://doi.org/10.1681/asn.2016121344
https://doi.org/10.1681/asn.2016121344
Autor:
Chris Altmann, Katja M. Gist, Evelyn Bodoni, Sarah Faubel, John R. Montford, Lara A. Kirkbride-Romeo, Kayo Okamura, Charles L. Edelstein, Zhiying You, Judith Blaine, Danielle E. Soranno, Radu Moldovan, Haichun Yang, Nataliya I. Skrypnyk, Benjamin R. Griffin
Publikováno v:
Kidney Int
Neutrophil gelatinase associated lipocalin (NGAL, Lcn2) is the most widely studied biomarker of acute kidney injury (AKI). Previous studies have demonstrated that NGAL is produced by the kidney and released into the urine and plasma. Consequently, NG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea49de6160070b04a0f2cf828320a00d
https://pubmed.ncbi.nlm.nih.gov/32444098
https://pubmed.ncbi.nlm.nih.gov/32444098
Autor:
Seth B. Furgeson, John R. Montford, David J. Orlicky, Raphael A. Nemenoff, Allison M.B. Lehman, Suman Ranjit, Evgenia Dobrinskikh, Enrico Gratton, Moshe Levi, Alexander Dvornikov
Publikováno v:
Kidney International. 90:1123-1128
All forms of progressive renal diseases develop a final pathway of tubulointerstitial fibrosis and glomerulosclerosis. Renal fibrosis is usually quantified using histological staining, a process that is time-consuming and pathologist dependent. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c1ae9bd967a6b260ad7afbc7da64e2
https://doi.org/10.1016/j.kint.2016.06.030
https://doi.org/10.1016/j.kint.2016.06.030