Detection of Blood Clots Using a Whole Stent as an Active Implantable Biosensor

Autor: Mahmut Talha Kirimi, Daniel Hoare, Michael Holsgrove, Jakup Czyzewski, Nosrat Mirzai, John R. Mercer, Steve L. Neale

Publikováno v: Advanced Science, Vol 11, Iss 21, Pp n/a-n/a (2024)

Abstract Many cardiovascular problems stem from blockages that form within the vasculature and often treatment includes fitting a stent through percutaneous coronary intervention. This offers a minimally invasive therapy but re‐occlusion through re

Externí odkaz: https://doaj.org/article/c824618a167b4d9090910748652ba05a

Predicting Cardiovascular Stent Complications Using Self‐Reporting Biosensors for Noninvasive Detection of Disease

Autor: Daniel Hoare, Andreas Tsiamis, Jamie R. K. Marland, Jakub Czyzewski, Mahmut T. Kirimi, Michael Holsgrove, Ewan Russell, Steven L. Neale, Nosrat Mirzai, Srinjoy Mitra, John R. Mercer

Publikováno v: Advanced Science, Vol 9, Iss 15, Pp n/a-n/a (2022)

Abstract Self‐reporting implantable medical devices are the future of cardiovascular healthcare. Cardiovascular complications such as blocked arteries that lead to the majority of heart attacks and strokes are frequently treated with inert metal st

Externí odkaz: https://doaj.org/article/320f38c1304f490493c804a247617ef6

Impedimetric Detection and Electromediated Apoptosis of Vascular Smooth Muscle Using Microfabricated Biosensors for Diagnosis and Therapeutic Intervention in Cardiovascular Diseases

Autor: Anubhav Bussooa, Daniel Hoare, Mahmut T. Kirimi, Srinjoy Mitra, Nosrat Mirzai, Steve L. Neale, John R. Mercer

Publikováno v: Advanced Science, Vol 7, Iss 18, Pp n/a-n/a (2020)

Abstract Cardiovascular diseases remain a significant global burden with 1‐in‐3 of all deaths attributable to the consequences of the disease. The main cause is blocked arteries which often remain undetected. Implantable medical devices (IMDs) su

Externí odkaz: https://doaj.org/article/abd99095d8ed42adb343cb53ab777db0

Toward Synthetic Vascular Graft Monitoring Using a Flip-Chip-on-Flex Impedance Spectroscopy Sensor

Autor: Jamie R. K. Marland, Andreas Tsiamis, Daniel Hoare, Pablo G. Ledesma Lopez, Steven L. Neale, John R. Mercer, Srinjoy Mitra

Publikováno v: Marland, J R K, Tsiamis, A, Hoare, D, Ledesma Lopez, P G, Neale, S L, Mercer, J R & Mitra, S 2022, ' Towards Synthetic Vascular Graft Monitoring Using a Flip-Chip-on-Flex Impedance Spectroscopy Sensor ', IEEE Sensors Journal . https://doi.org/10.1109/JSEN.2022.3220022

Synthetic vascular grafts are used in a wide range of clinical applications. However, they can become prone to occlusion over time, due to growth of vascular smooth muscle cells (VSMC). This phenomenon is associated with graft failure. Here, we descr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09efdb1f8e17503be4f77f810226f824
https://doi.org/10.1109/jsen.2022.3220022

Impaired mitochondrial respiration in human carotid plaque atherosclerosis: A potential role for Pink1 in vascular smooth muscle cell energetics

Autor: Craig K, Docherty, Andy, Carswell, Elaine, Friel, John R, Mercer

Publikováno v: Atherosclerosis

Background and aims DNA damage and mitochondrial dysfunction are thought to play an essential role in ageing and the energetic decline of vascular smooth muscle cells (VSMCs) essential for maintaining plaque integrity. We aimed to better understand V

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d72e8547d62039c463dc91449f354c70
https://pubmed.ncbi.nlm.nih.gov/29156421