Essential requirements for the governance and management of data trusts, data repositories, and other data collaborations

Autor: P Alison Paprica, Monique Crichlow, Donna Curtis Maillet, Sarah Kesselring, Conrad Pow, Thomas P. Scarnecchia, Michael J. Schull, Rosario G. Cartagena, Annabelle Cumyn, Salman Dostmohammad, Keith O. Elliston, Michelle Greiver, Amy Hawn Nelson, Sean L. Hill, Wanrudee Isaranuwatchai, Evgueni Loukipoudis, James Ted McDonald, John R. McLaughlin, Alan Rabinowitz, Fahad Razak, Stefaan G. Verhulst, Amol A. Verma, J. Charles Victor, Andrew Young, Joanna Yu, Kimberlyn McGrail

Publikováno v: International Journal of Population Data Science, Vol 8, Iss 4 (2023)

Introduction Around the world, many organisations are working on ways to increase the use, sharing, and reuse of person-level data for research, evaluation, planning, and innovation while ensuring that data are secure and privacy is protected. As a c

Externí odkaz: https://doaj.org/article/940b2c3308a8427586a6aa4c7e236fc9

Non-Hodgkin lymphoma risk and organophosphate and carbamate insecticide use in the north American pooled project

Autor: Stella Koutros, Shelley A. Harris, John J. Spinelli, Aaron Blair, John R. McLaughlin, Shelia Hoar Zahm, Sungduk Kim, Paul S. Albert, Linda Kachuri, Manisha Pahwa, Kenneth P. Cantor, Dennis D. Weisenburger, Punam Pahwa, Larissa A. Pardo, James A. Dosman, Paul A. Demers, Laura E. Beane Freeman

Publikováno v: Environment International, Vol 127, Iss , Pp 199-205 (2019)

Organophosphates and carbamates have been among the most commonly used insecticides, with both agricultural and residential uses. Previous studies have suggested associations of non-Hodgkin lymphoma (NHL) with some of these chemicals; however, many s

Externí odkaz: https://doaj.org/article/b9db3f1488a1473fa6ed27635caf6e9b

Association of rs2282679 A>C polymorphism in vitamin D binding protein gene with colorectal cancer risk and survival: effect modification by dietary vitamin D intake

Autor: Yun Zhu, Peizhong Peter Wang, Guangju Zhai, Bharati Bapat, Sevtap Savas, Jennifer R. Woodrow, Peter T. Campbell, Yuming Li, Ning Yang, Xin Zhou, Elizabeth Dicks, John R. Mclaughlin, Patrick S. Parfrey

Publikováno v: BMC Cancer, Vol 18, Iss 1, Pp 1-12 (2018)

Abstract Background The rs2282679 A>C polymorphism in the vitamin D binding protein gene is associated with lower circulating levels of vitamin D. We investigated associations of this SNP with colorectal cancer (CRC) risk and survival and whether the

Externí odkaz: https://doaj.org/article/fee742d83d5042b18f2a6f69e0611c07

rs495139 in the TYMS-ENOSF1 Region and Risk of Ovarian Carcinoma of Mucinous Histology

Autor: Linda E. Kelemen, Madalene Earp, Brooke L. Fridley, Georgia Chenevix-Trench, on behalf of Australian Ovarian Cancer Study Group, Peter A. Fasching, Matthias W. Beckmann, Arif B. Ekici, Alexander Hein, Diether Lambrechts, Sandrina Lambrechts, Els Van Nieuwenhuysen, Ignace Vergote, Mary Anne Rossing, Jennifer A. Doherty, Jenny Chang-Claude, Sabine Behrens, Kirsten B. Moysich, Rikki Cannioto, Shashikant Lele, Kunle Odunsi, Marc T. Goodman, Yurii B. Shvetsov, Pamela J. Thompson, Lynne R. Wilkens, Thilo Dörk, Natalia Antonenkova, Natalia Bogdanova, Peter Hillemanns, Ingo B. Runnebaum, Andreas du Bois, Philipp Harter, Florian Heitz, Ira Schwaab, Ralf Butzow, Liisa M. Pelttari, Heli Nevanlinna, Francesmary Modugno, Robert P. Edwards, Joseph L. Kelley, Roberta B. Ness, Beth Y. Karlan, Jenny Lester, Sandra Orsulic, Christine Walsh, Susanne K. Kjaer, Allan Jensen, Julie M. Cunningham, Robert A. Vierkant, Graham G. Giles, Fiona Bruinsma, Melissa C. Southey, Michelle A.T. Hildebrandt, Dong Liang, Karen Lu, Xifeng Wu, Thomas A. Sellers, Douglas A. Levine, Joellen M. Schildkraut, Edwin S. Iversen, Kathryn L. Terry, Daniel W. Cramer, Shelley S. Tworoger, Elizabeth M. Poole, Elisa V. Bandera, Sara H. Olson, Irene Orlow, Liv Cecilie Vestrheim Thomsen, Line Bjorge, Camilla Krakstad, Ingvild L. Tangen, Lambertus A. Kiemeney, Katja K.H. Aben, Leon F.A.G. Massuger, Anne M. van Altena, Tanja Pejovic, Yukie Bean, Melissa Kellar, Linda S. Cook, Nhu D. Le, Angela Brooks-Wilson, Jacek Gronwald, Cezary Cybulski, Anna Jakubowska, Jan Lubiński, Nicolas Wentzensen, Louise A. Brinton, Jolanta Lissowska, Estrid Hogdall, Svend Aage Engelholm, Claus Hogdall, Lene Lundvall, Lotte Nedergaard, Paul D.P. Pharoah, Ed Dicks, Honglin Song, Jonathan P. Tyrer, Iain McNeish, Nadeem Siddiqui, Karen Carty, Rosalind Glasspool, James Paul, Ian G. Campbell, Diana Eccles, Alice S. Whittemore, Valerie McGuire, Joseph H. Rothstein, Weiva Sieh, Steven A. Narod, Catherine M. Phelan, John R. McLaughlin, Harvey A. Risch, Hoda Anton-Culver, Argyrios Ziogas, Usha Menon, Simon A. Gayther, Aleksandra Gentry-Maharaj, Susan J. Ramus, Anna H. Wu, Celeste Leigh Pearce, Alice W. Lee, Malcolm C. Pike, Jolanta Kupryjanczyk, Agnieszka Podgorska, Joanna Plisiecka-Halasa, Wlodzimierz Sawicki, Ellen L. Goode, Andrew Berchuck, Ovarian Cancer Association Consortium

Publikováno v: International Journal of Molecular Sciences, Vol 19, Iss 9, p 2473 (2018)

Thymidylate synthase (TYMS) is a crucial enzyme for DNA synthesis. TYMS expression is regulated by its antisense mRNA, ENOSF1. Disrupted regulation may promote uncontrolled DNA synthesis and tumor growth. We sought to replicate our previously reporte

Externí odkaz: https://doaj.org/article/3dc3fa85aae44edf934065217f878cf9

Impact of germline mutations in cancer-predisposing genes on long-term survival in patients with epithelial ovarian cancer

Autor: Joanne Kotsopoulos, Neda Zamani, Barry Rosen, John R. McLaughlin, Harvey A. Risch, Shana J. Kim, Ping Sun, Mohammad Reza Akbari, Steven A. Narod

Publikováno v: Br J Cancer

BACKGROUND: Several clinical and tumour factors impact on ovarian cancer survival. It is important to evaluate if germline mutations impact long-term outcomes among patients with epithelial ovarian cancer. METHODS: We followed 1422 Ontario women with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9704f1fa60cf51bab97967563fabbcb
https://doi.org/10.1038/s41416-022-01840-4