Výsledky vyhledávání - "John R. Mclaughlin"

Akademický článek

Associations between polymorphisms in leptin and leptin receptor genes and colorectal cancer survival

Autor: Meizhi Du, Yu Wang, Jillian Vallis, Matin Shariati, Patrick S. Parfrey, John R. Mclaughlin, Peizhong Peter Wang, Yun Zhu

Publikováno v: Cancer Biology & Medicine, Vol 20, Iss 6, Pp 438-451 (2023)

Objective: Leptin (LEP) is an obesity-associated adipokine associated with tumor cell growth. We examined the relevance of genetic variants of LEP and leptin receptor (LEPR) to colorectal cancer (CRC) survival by using data from the Newfoundland Fami

Externí odkaz: https://doaj.org/article/41ab7b80abac4cc5a397dfb501a92abe

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Akademický článek

Essential requirements for the governance and management of data trusts, data repositories, and other data collaborations

Publikováno v: International Journal of Population Data Science, Vol 8, Iss 4 (2023)

Introduction Around the world, many organisations are working on ways to increase the use, sharing, and reuse of person-level data for research, evaluation, planning, and innovation while ensuring that data are secure and privacy is protected. As a c

Externí odkaz: https://doaj.org/article/940b2c3308a8427586a6aa4c7e236fc9

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Akademický článek

Non-Hodgkin lymphoma risk and organophosphate and carbamate insecticide use in the north American pooled project

Autor: Stella Koutros, Shelley A. Harris, John J. Spinelli, Aaron Blair, John R. McLaughlin, Shelia Hoar Zahm, Sungduk Kim, Paul S. Albert, Linda Kachuri, Manisha Pahwa, Kenneth P. Cantor, Dennis D. Weisenburger, Punam Pahwa, Larissa A. Pardo, James A. Dosman, Paul A. Demers, Laura E. Beane Freeman

Publikováno v: Environment International, Vol 127, Iss , Pp 199-205 (2019)

Organophosphates and carbamates have been among the most commonly used insecticides, with both agricultural and residential uses. Previous studies have suggested associations of non-Hodgkin lymphoma (NHL) with some of these chemicals; however, many s

Externí odkaz: https://doaj.org/article/b9db3f1488a1473fa6ed27635caf6e9b

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Akademický článek

Hypothesis and data-driven dietary patterns and colorectal Cancer survival: findings from Newfoundland and Labrador colorectal Cancer cohort

Autor: Ishor Sharma, Barbara Roebothan, Yun Zhu, Jennifer Woodrow, Patrick S. Parfrey, John R. Mclaughlin, Peter Peizhong Wang

Publikováno v: Nutrition Journal, Vol 17, Iss 1, Pp 1-9 (2018)

Abstract Background Dietary patterns are commonly used in epidemiological research, yet there have been few studies assessing if and how research results may vary across dietary patterns. This study aimed to estimate the risk of mortality/recurrence/

Externí odkaz: https://doaj.org/article/dd2e675a1dcc4ac98735637933552273

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Akademický článek

Association of rs2282679 A>C polymorphism in vitamin D binding protein gene with colorectal cancer risk and survival: effect modification by dietary vitamin D intake

Autor: Yun Zhu, Peizhong Peter Wang, Guangju Zhai, Bharati Bapat, Sevtap Savas, Jennifer R. Woodrow, Peter T. Campbell, Yuming Li, Ning Yang, Xin Zhou, Elizabeth Dicks, John R. Mclaughlin, Patrick S. Parfrey

Publikováno v: BMC Cancer, Vol 18, Iss 1, Pp 1-12 (2018)

Abstract Background The rs2282679 A>C polymorphism in the vitamin D binding protein gene is associated with lower circulating levels of vitamin D. We investigated associations of this SNP with colorectal cancer (CRC) risk and survival and whether the

Externí odkaz: https://doaj.org/article/fee742d83d5042b18f2a6f69e0611c07

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Akademický článek

Primary care physicians’ perspectives on computer-based health risk assessment tools for chronic diseases: a mixed methods study

Autor: Teja Voruganti, Mary Ann O'Brien, Sharon E. Straus, John R. McLaughlin, Eva Grunfeld

Publikováno v: Journal of Innovation in Health Informatics, Vol 22, Iss 3, Pp 333-339 (2015)

Background Health risk assessment tools compute an individual’s risk of developing a disease. Routine use of such tools by primary care physicians (PCPs) is potentially useful in chronic disease prevention. We sought physicians’ awareness and per

Externí odkaz: https://doaj.org/article/74b594a1031e45c9a73a813fde3686f8

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Akademický článek

Application of two job indices for general occupational demands in a pooled analysis of case–control studies on lung cancer

Publikováno v: Scandinavian Journal of Work, Environment & Health, Vol 47, Iss 6, Pp 475-481 (2021)

OBJECTIVES: We investigated general job demands as a risk factor for lung cancer as well as their role in the association between occupational prestige and lung cancer. METHODS: In 13 case–control studies on lung cancer, as part of the internationa

Externí odkaz: https://doaj.org/article/1480d21066174242abd8ad7a8fa66ef8

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Akademický článek

Glyphosate use and associations with non-Hodgkin lymphoma major histological sub-types: findings from the North American Pooled Project

Autor: Manisha Pahwa, Laura E Beane Freeman, John J Spinelli, Aaron Blair, John R McLaughlin, Shelia Hoar Zahm, Kenneth P Cantor, Dennis D Weisenburger, Punam Pahwa Punam Pahwa, James A Dosman, Paul A Demers, Shelley A Harris

Publikováno v: Scandinavian Journal of Work, Environment & Health, Vol 45, Iss 6, Pp 600-609 (2019)

OBJECTIVES: Some epidemiological studies have suggested positive associations between glyphosate use and non-Hodgkin lymphoma (NHL), but evidence is inconsistent and few studies could evaluate histological sub-types. Here, associations between glypho

Externí odkaz: https://doaj.org/article/9a1d28160be440d7953fbc48939836d6

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