Zobrazeno 1 - 10
of 195
pro vyhledávání: '"John R. Ingram"'
Autor:
Alexa B. Kimball, Joslyn Kirby, John R. Ingram, Tanja Tran, Ingrid Pansar, Valerie Ciaravino, Damon Willems, Anne-Mary Lewis-Mikhael, Vanita Tongbram, Amit Garg
Publikováno v:
Dermatology and Therapy, Vol 14, Iss 1, Pp 83-98 (2024)
Abstract Introduction Hidradenitis suppurativa (HS) has a profound negative impact on patients’ health-related quality of life (HRQoL). Here we summarize the evidence on HRQoL and Patient Reported Outcomes (PROs) in patients with HS in real-world s
Externí odkaz:
https://doaj.org/article/4cbe89b28d9a407281fa1c8e886e9636
Autor:
Angela L. Bosma, MD, Wouter Ouwerkerk, PhD, Madeline J. Heidema, MD, David Prieto-Merino, PhD, Michael R. Ardern-Jones, MD, PhD, Paula Beattie, MD, Sara J. Brown, MD, PhD, John R. Ingram, MD, PhD, Alan D. Irvine, MD, DSc, Graham Ogg, MD, PhD, Prakash Patel, BSc, Nick J. Reynolds, MD, PhD, R.M. Ross Hearn, MD, Mandy Wan, PhD, Richard B. Warren, MD, PhD, Richard T. Woolf, MD, PhD, Ariënna M. Hyseni, Louise A.A. Gerbens, MD, PhD, Phyllis I. Spuls, MD, PhD, Carsten Flohr, MD, PhD, Maritza A. Middelkamp-Hup, MD, PhD
Publikováno v:
JAAD International, Vol 10, Iss , Pp 14-24 (2023)
Background: Few data exist on differences in treatment effectiveness and safety in atopic dermatitis patients of different skin types. Objective: To investigate treatment outcomes of dupilumab, methotrexate, and ciclosporin, and morphological phenoty
Externí odkaz:
https://doaj.org/article/a6000db7359b4ce99fcb0c5dc46847c7
Autor:
Victoria J. Tyrrell, Faraz Ali, William E. Boeglin, Robert Andrews, James Burston, James C. Birchall, John R. Ingram, Robert C. Murphy, Vincent Piguet, Alan R. Brash, Valerie B. O'Donnell, Christopher P. Thomas
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100094- (2021)
A complex assembly of lipids including fatty acids, cholesterol, and ceramides is vital to the integrity of the mammalian epidermal barrier. The formation of this barrier requires oxidation of the substrate fatty acid, linoleic acid (LA), which is in
Externí odkaz:
https://doaj.org/article/da95d04e315a448bb3ecd72b7c0d5f1e
Autor:
Tayaza Fadason, William Schierding, Nikolai Kolbenev, Jiamou Liu, John R. Ingram, Justin M. O’Sullivan
Publikováno v:
Metabolism Open, Vol 6, Iss , Pp 100035- (2020)
Background: —Maintenance of tight controls on circulating blood metabolites is crucial to normal, healthy tissue and organismal function. A number of single nucleotide polymorphisms (SNPs) have been associated with changes in the levels of blood me
Externí odkaz:
https://doaj.org/article/5bb51376258145d7b52a8cf7f2af6d7c
Autor:
Shanthi G. Parkar, Patricia Davis, Tania M. Trower, Duncan I. Hedderley, Kevin H. Sutton, John R. Ingram
Publikováno v:
Journal of Nutrition & Intermediary Metabolism, Vol 15, Iss , Pp 55-57 (2019)
In vitro fermentations using human fecal bacteria are an often used high through put strategy to evaluate the prebiotic potential of food ingredients. We investigated the influence of the substrate presented to fecal microbiota by monitoring the micr
Externí odkaz:
https://doaj.org/article/edc81a097e5a44cbb56ac208ed3c1c39
Publikováno v:
Frontiers in Genetics, Vol 8 (2017)
The mechanisms that underlie the association between obesity and type 2 diabetes are not fully understood. Here, we investigated the role of the 3D genome organization in the pathogeneses of obesity and type-2 diabetes. We interpreted the combined an
Externí odkaz:
https://doaj.org/article/db2b6738565e4841abe8da2e583c1874
Publikováno v:
Biomolecules, Vol 9, Iss 9, p 390 (2019)
Hop cones (Humulus lupulus L.) have been used throughout history as an additive in beer brewing and as herbal supplements with medicinal and culinary properties. The objective of this study was to ascertain the effect of a range of concentrations of
Externí odkaz:
https://doaj.org/article/545f90fe996342eb8d883e07397af22b
Autor:
Amit Garg, Sahil Rawal, Oleg Akilov, Afsaneh Alavi, Christine Ardon, Falk G Bechara, Arnon D Cohen, Steven R Cohen, Steven Daveluy, Véronique del Marmol, Maïa Delage, Solveig Esmann, Shani Fisher, Evangelos J Giamarellos-Bourboulis, Amelia Glowaczewska, Noah Goldfarb, Elena Gonzalez Brant, Øystein Grimstad, Sandra Guilbault, Iltefat Hamzavi, Rosalind Hughes, John R Ingram, Gregor B E Jemec, Qiang Ju, Naomi Kappe, Brian Kirby, Joslyn S Kirby, Michelle A Lowes, Lukasz Matusiak, Stella Micha, Robert G Micheletti, Angela P Miller, Dagfinn Moseng, Haley B Naik, Aude Nassif, Georgios Nikolakis, So Yeon Paek, Jose Carlos Pascual, Errol Prens, Barry Resnik, Hassan Riad, Christopher Sayed, Saxon D Smith, Yssra Soliman, Jacek C Szepietowski, Jerry Tan, Linnea Thorlacius, Thrasyvoulos Tzellos, Hessel H van der Zee, Bente Villumsen, Lanqi Wang, Christos C Zouboulis, Andrew Strunk
Publikováno v:
British Journal of Dermatology. 188:808-810
Patients with hidradenitis suppurativa experience significant life impact related to their disease. Younger age, Black race, high BMI, active smoking, flares, depression, anxiety, high comorbidity burden, disability, and difficult access to a dermato
Publikováno v:
Experimental Dermatology. 31:33-39
Research interest in Hidradenitis Suppurativa (HS) has grown exponentially over the past decades. Several groups have worked to develop novel scores that address the drawbacks of existing investigator-assessed and patient-reported outcome measures cu
Publikováno v:
British Journal of General Practice. 73:43-45