Zobrazeno 1 - 7
of 7
pro vyhledávání: '"John R. Hartono"'
Autor:
Christopher Y. Lu, Glenn T. Nagami, Keng Mean Lin, Xin J. Zhou, Yanxia Wang, James A. Richardson, John R. Hartono, Pamela D. Winterberg, John M. Shelton
Publikováno v:
American Journal of Physiology-Renal Physiology. 305:F164-F172
We previously reported that expression of the transcription factor interferon regulatory factor 1 (IRF1) is an early, critical maladaptive signal expressed by renal tubules during murine ischemic acute kidney injury (AKI). We now show that IRF1 media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a40c1855b1ac446f88eff586ec02f3f
https://doi.org/10.1152/ajprenal.00487.2012
https://doi.org/10.1152/ajprenal.00487.2012
Autor:
Xin Jin Zhou, Pamela D. Winterberg, Michael J. Bennett, Christopher Y. Lu, Qingqing Wu, Jianlin Chen, Reji John, Glenn T. Nagami, John R. Hartono, Yanxia Wang
Publikováno v:
Kidney International. 80:504-515
Although leukocytes infiltrate the kidney during ischemic acute kidney injury (AKI) and release interleukin 6 (IL6), their mechanism of activation is unknown. Here, we tested whether Toll-like receptor 4 (TLR4) on leukocytes mediated this activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::814d91379ec9f478722762aa6fb7115d
https://doi.org/10.1038/ki.2011.140
https://doi.org/10.1038/ki.2011.140
Autor:
Martin Senitko, Pamela D. Winterberg, Xin J. Zhou, Colin J. Meyer, Qingqing Wu, Jianlin Chen, Yanxia Wang, John R. Hartono, Deborah A. Ferguson, Bo Chen, Anapam Agarwal, Christopher Y. Lu, W. Christian Wigley, Eric Ben Grossman
Publikováno v:
American Journal of Physiology-Renal Physiology. 300:F1180-F1192
Ischemic acute kidney injury (AKI) triggers expression of adaptive (protective) and maladaptive genes. Agents that increase expression of protective genes should provide a therapeutic benefit. We now report that bardoxolone methyl (BARD) ameliorates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a96bf8e4ad521f4526e7e67761ab7b49
https://doi.org/10.1152/ajprenal.00353.2010
https://doi.org/10.1152/ajprenal.00353.2010
Autor:
Yanxia Wang, Xin J. Zhou, John M. Shelton, Reji John, Jianlin Chen, James A. Richardson, John R. Hartono, Qingqing Wu, Pamela D. Winterberg, Christopher Y. Lu
Publikováno v:
Kidney International. 79(3):288-299
Ischemic acute kidney injury (AKI) triggers an inflammatory response which exacerbates injury that requires increased expression of endothelial adhesion molecules. To study this further, we used in situ hybridization, immunohistology, and isolated en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864e0fe9ead32f5426e05f9f5ff881be
Publikováno v:
Current Opinion in Nephrology and Hypertension. 16:83-89
Purpose of review Ischemic acute kidney injury may be exacerbated by an inflammatory response. How injury elicits inflammation remains a major question in understanding acute kidney injury. The present review examines the hypothesis that molecules re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b526aec7096c3522640752e58070c6fe
https://doi.org/10.1097/mnh.0b013e3280403c4e
https://doi.org/10.1097/mnh.0b013e3280403c4e
Publikováno v:
Pediatric nephrology (Berlin, Germany). 27(10)
Ischemic acute kidney injury (AKI) contributes to considerable morbidity and mortality in hospitalized patients and can contribute to rejection during kidney transplantation. Maladaptive immune responses can exacerbate injury, and targeting these res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8854c61baf8311802a9e928d1358cf9c
https://pubmed.ncbi.nlm.nih.gov/22033798
https://pubmed.ncbi.nlm.nih.gov/22033798
Autor:
John R. Hartono, Martin Senitko, Miguel A. Vazquez, Juan D. Arenas, Peter Stastny, Bhavna Lavingia, Christopher Y. Lu
Publikováno v:
Journal of Medical Case Reports
Journal of Medical Case Reports, Vol 3, Iss 1, p 41 (2009)
Journal of Medical Case Reports, Vol 3, Iss 1, p 41 (2009)
Introduction Hyperacute rejection may be prevented by avoiding the transplantation of kidneys into patients with pre-existing anti-donor Class I human leukocyte antigen antibodies. However, the role of anti-donor-Class II-human leukocyte antigen-DQ a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caca9fa4dec4748f21f3caadfeb4a877