Zobrazeno 1 - 10
of 41
pro vyhledávání: '"John R. Coombs"'
Autor:
Melissa Cadena, Roberto Silva Villatoro, Jyoti Shah Gupta, Cody Phillips, Jonathan B. Allen, Hadi D. Arman, Daniel J. Wherritt, Nicholas A. Clanton, Alexander L. Ruchelman, Eric M. Simmons, Albert J. DelMonte, John R. Coombs, Doug E. Frantz
Publikováno v:
ACS Catalysis. 12:10199-10206
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::379e4f00da246e85aa7c2d7f936ca89c
https://doi.org/10.1021/acscatal.2c02783
https://doi.org/10.1021/acscatal.2c02783
Publikováno v:
ACS Symposium Series ISBN: 9780841297333
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb9277d2bd95e00bd2aec718ec579404
https://doi.org/10.1021/bk-2022-1423.ch006
https://doi.org/10.1021/bk-2022-1423.ch006
Autor:
John R. Coombs, Jason Zhu, Francisco González-Bobes, Sanjeewa Rupasinghe, Kishta Katipally, Boguslaw Mudryk, William P. Gallagher, Carlos A. Guerrero, Candice L. Joe
Publikováno v:
Organic Process Research & Development. 26:583-591
The cyclohexyl fragment 1 in BMS-986251 was synthesized starting from Hagemann’s ester 2 in 7 steps and 5 isolations. The route is highlighted by a dynamic kinetic resolution (DKR), a telescoped en...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17ea0653ff5238432d57a80b901be60b
https://doi.org/10.1021/acs.oprd.1c00339
https://doi.org/10.1021/acs.oprd.1c00339
Autor:
William P. Gallagher, Francisco González-Bobes, Carlos A. Guerrero, John R. Coombs, Eric M. Simmons
Publikováno v:
Organic Process Research & Development. 26:592-600
We have devised an asymmetric route to the tricyclic core 10 of BMS-986251. The six-step synthesis utilizes readily available starting materials, involves the one-step installation of the perfluoro...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f04ffb511e5b6a9e9fe69e0a9725a8f
https://doi.org/10.1021/acs.oprd.1c00338
https://doi.org/10.1021/acs.oprd.1c00338
Synthesis of novel AB2 monomers for the construction of highly branched macromolecular architectures
Autor:
Rebecca M. Triano, Matthew P. Tracey, Scott Pomarico, Michele L. Paccagnini, John R. Coombs, Tom P. Carberry, Amy M. Balija
Publikováno v:
ARKIVOC, Vol 2015, Iss 5, Pp 350-365 (2015)
Externí odkaz:
https://doaj.org/article/edf175bde5814242896c00e5091e73da
Autor:
John R. Coombs, Francisco González-Bobes, Boguslaw Mudryk, Arun Vinodini, Sankar Kuppusamy, Candice L. Joe, Senthil Palani, Muthukrishnan Ponnusamy, Vedhachalam Nagappan, Rajappa Vaidyanathan, William P. Gallagher, Aravind S. Gangu, Martin D. Eastgate, Sanjeewa Rupasinghe, Alla Venu, Nathaniel Kopp, Srinivas Kalidindi, Shankar Tendulkar
Publikováno v:
Organic Process Research & Development. 25:1547-1555
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be5d45a55c301e242d68690ce145b08c
https://doi.org/10.1021/acs.oprd.1c00124
https://doi.org/10.1021/acs.oprd.1c00124
Autor:
Robert Wethman, Keary M. Engle, Joseph Derosa, Van T. Tran, Steven R. Wisniewski, Omar Apolinar, Taeho Kang, John R. Coombs, Roman Kleinmans, Anuji Abraham
Publikováno v:
ACS Catalysis. 11:502-508
The decomposition of primary sodium alkoxide salts under ambient storage conditions and the effects of this phenomenon on commonly employed transition-metal-catalyzed cross-coupling reactions are described. By utilizing NMR, IR, and Raman spectroscop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13f7797066931e57b1c17d25f1dae74e
https://doi.org/10.1021/acscatal.0c04124
https://doi.org/10.1021/acscatal.0c04124
Autor:
John Hynes, Antonio Ramirez, John R. Coombs, Jade McDaniel, David Marcoux, Francisco González-Bobes, T. G. Murali Dhar, Amy A. Sarjeant, Arthur Han, Qing Shi, Christopher A. Farley, William P. Gallagher, Bhupinder Sandhu
Publikováno v:
Organic Letters. 23:60-65
The use of the unprecedented annulating reagents methyl N-(tert-butylsulfinyl)-4-chlorobutanimidate and methyl N-(tert-butylsulfinyl)-5-bromopentanimidate enables the diastereoselective preparation of 5- and 6-membered carbocycles bearing three conti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74155f755af11fec471be78e17587fdd
https://doi.org/10.1021/acs.orglett.0c03695
https://doi.org/10.1021/acs.orglett.0c03695
Autor:
Francisco González-Bobes, John R. Coombs, Lucas W. Hernandez, William P. Gallagher, Carlos A. Guerrero
Publikováno v:
The Journal of organic chemistry. 86(15)
The use of sodium dithionite with perfluoroalkyl iodides under basic conditions facilitates the direct perfluoroalkylation of arenes with pendant benzylic electron-withdrawing groups. This occurs via attack of the arene on the electrophilic perfluoro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe8ce6fba0f803e4c7dc82e575aeb034
https://pubmed.ncbi.nlm.nih.gov/34286987
https://pubmed.ncbi.nlm.nih.gov/34286987
Autor:
Steven R. Wisniewski, Gregory L. Beutner, Eric M. Simmons, Rebecca A. Green, Bahar Inankur, Frederick Roberts, John R. Coombs, Dong Lin, Jun Qiu
Publikováno v:
Organic Process Research & Development. 23:1529-1537
The palladium-catalyzed coupling of aryl and heteroaryl chlorides with primary amides under mild homogeneous reaction conditions is reported. Successful C–N coupling is enabled by the use of a uniq...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71112f3a35660032fd2d70d21db6603d
https://doi.org/10.1021/acs.oprd.9b00196
https://doi.org/10.1021/acs.oprd.9b00196