Zobrazeno 1 - 10
of 445
pro vyhledávání: '"John R White"'
Autor:
John R White, Sammina Ahmed, Jan Amstrup, Petra Bennington, Zhijie Jey Cheng, Peter Day, Keneshia K Haenssen, Adi Kozminsky-Atias, Eva Martinez, Esther HQ Ong, Isam Qahwash, Elaine SE Stokes, Jenny Wang
Publikováno v:
BioTechniques, Vol 76, Iss 4, Pp 135-144 (2024)
The BioPhorum Development Group is an industry collaboration enabling the sharing of common practices for the development of biopharmaceuticals. Bioassays are an important part of an analytical control system. Utilization of ready-to-use cells can in
Externí odkaz:
https://doaj.org/article/906e6b3860584bce95f046732311ad20
Autor:
Kathleen Van Manen-Brush, Jacob Zeitler, John R White, Paul Younge, Samantha Willis, Marisa Jones
Publikováno v:
BioTechniques, Vol 69, Iss 3, Pp 186-192 (2020)
Chinese hamster ovary (CHO) cells are a mammalian cell line used in the production of therapeutic proteins. Host cell proteins (HCPs) are process-related impurities that are derived from the host cell expression system. During biopharmaceutical drug
Externí odkaz:
https://doaj.org/article/1fcc32b0ba1645b7b6328b8fe1c3cbf3
Autor:
Shu-Min Zhang, Matthew Roberts, Marisa Jones, Jacob Zeitler, Greg Kilby, Aston Liu, John R White
Publikováno v:
BioTechniques, Vol 68, Iss 6, Pp 353-358 (2020)
Polyethyleneimine (PEI) is a flocculent that is widely used in the downstream purification of monoclonal antibodies. It is an in-process residual that is carried through the drug purification process and strongly inhibits residual DNA quantitation by
Externí odkaz:
https://doaj.org/article/9ab2508e54994f6785b529f2abe5e12d
Autor:
Jean-Bernard Duchemin, John R White, Antonio Di Rubbo, Shunin Shi, Gert Johannes Venter, Ian Holmes, Peter J Walker
Publikováno v:
Veterinaria Italiana, Vol 57, Iss 4 (2021)
Following the emerging bluetongue virus transmission in European temperate regions, we question the vector competence of the abundant Culicoides austropalpalis Lee and Reye in South-East temperate Australia. Field collected Culicoides midges were mem
Externí odkaz:
https://doaj.org/article/00d0fcbd8c14471aab4c8be46cc914a1
Autor:
John R White, Marla Abodeely, Sammina Ahmed, Gaël Debauve, Evan Johnson, Debra M Meyer, Ned M Mozier, Matthias Naumer, Alessandra Pepe, Isam Qahwash, Edward Rocnik, Jeffrey G Smith, Elaine SE Stokes, Jeffrey J Talbot, Pin Yee Wong
Publikováno v:
BioTechniques, Vol 67, Iss 3, Pp 126-137 (2019)
Biological activity is a critical quality attribute for biopharmaceuticals, which is accurately measured using an appropriate relative potency bioassay. Developing a bioassay is a complex, rigorous undertaking that needs to address several challenges
Externí odkaz:
https://doaj.org/article/a956d410bab14152a653a980043013fe
Autor:
Susan B Laffan, Andrew S Thomson, Shing Mai, Cindy Fishman, Takahito Kambara, Kiran Nistala, James T Raymond, Shugui Chen, Thulasi Ramani, Laura Pageon, Rodd Polsky, Mark Watkins, Gemma Ottolangui, John R White, Curtis Maier, Michael Herdman, Gerben Bouma
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231655 (2020)
Despite the potential for the chemokine class as therapeutic targets in immune mediated disease, success has been limited. Many chemokines can bind to multiple receptors and many receptors have multiple ligands, with few exceptions. One of those exce
Externí odkaz:
https://doaj.org/article/ee33790a5c0946eb8e5ea303f460bcc0
Publikováno v:
Clinical and Translational Science, Vol 12, Iss 1, Pp 39-46 (2019)
The caffeine metabolic ratio is an established marker for cytochrome P450 (CYP) 1A2 activity. Optimal sample size calculation for clinical pharmacokinetic xenobiotic–caffeine interaction studies requires robust estimates of interindividual and intr
Externí odkaz:
https://doaj.org/article/cdf275a3890b4e16b1bb3ad69975aa68
Autor:
Rakshit S. Tanna, James T. Nguyen, Deena L. Hadi, Matthew E. Layton, John R. White, Nadja B. Cech, Nicholas H. Oberlies, Allan E. Rettie, Kenneth E. Thummel, Mary F. Paine
Publikováno v:
Clinical Pharmacology & Therapeutics. 113:1315-1325
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::541e2cbfe0ccb08f5b5c9e9e9a09bd7b
https://doi.org/10.1002/cpt.2891
https://doi.org/10.1002/cpt.2891
Publikováno v:
Soil Science Society of America Journal. 87:390-403
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de35b5b3700ee8bb095daeb3ec6654a2
https://doi.org/10.1002/saj2.20515
https://doi.org/10.1002/saj2.20515
Autor:
John W. Day, Robert R. Twilley, Angelina Freeman, Brady Couvillion, Tracy Quirk, Navid Jafari, Giulio Mariotti, Rachael Hunter, Charles Norman, G. Paul Kemp, John R. White, Ehab Meselhe
Publikováno v:
Nature-Based Solutions. 3:100061
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e20676e341262d6298dd25d72836aa3d
https://doi.org/10.1016/j.nbsj.2023.100061
https://doi.org/10.1016/j.nbsj.2023.100061