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We described a new method to estimate physostigmine in plasma. The method utilized a liquid/liquid, ion-pair extraction coupled with normal phase liquid chromatographic analysis and fluoresence detection. The limit of detection was 100 nanograms/mill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab6bbf6edabed5751bb762f907a0b804
https://doi.org/10.21236/ada199449
https://doi.org/10.21236/ada199449
Publikováno v:
Analytical biochemistry. 177(1)
Physostigmine (PHY) is an anticholinergic drug used in the treatment of neuromuscular disorders and organophosphate poisoning. We described a sensitive, accurate, and reproducible method for PHY determination in biological materials. The method utili