Zobrazeno 1 - 10 of 63 pro vyhledávání: '"John R Houck"'
1
Akademický článek
Genome-Wide Loss of Heterozygosity and DNA Copy Number Aberration in HPV-Negative Oral Squamous Cell Carcinoma and Their Associations with Disease-Specific Survival.
Autor: Chu Chen, Yuzheng Zhang, Melissa M Loomis, Melissa P Upton, Pawadee Lohavanichbutr, John R Houck, David R Doody, Eduardo Mendez, Neal Futran, Stephen M Schwartz, Pei Wang
Publikováno v: PLoS ONE, Vol 10, Iss 8, p e0135074 (2015)
Oral squamous cell cancer of the oral cavity and oropharynx (OSCC) is associated with high case-fatality. For reasons that are largely unknown, patients with the same clinical and pathologic staging have heterogeneous response to treatment and differ
Externí odkaz: https://doaj.org/article/d3b1939661aa4c31aeb44d80d6170b36
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2
Akademický článek
Integrative genomics in combination with RNA interference identifies prognostic and functionally relevant gene targets for oral squamous cell carcinoma.
Autor: Chang Xu, Pei Wang, Yan Liu, Yuzheng Zhang, Wenhong Fan, Melissa P Upton, Pawadee Lohavanichbutr, John R Houck, David R Doody, Neal D Futran, Lue Ping Zhao, Stephen M Schwartz, Chu Chen, Eduardo Méndez
Publikováno v: PLoS Genetics, Vol 9, Iss 1, p e1003169 (2013)
In oral squamous cell carcinoma (OSCC), metastasis to lymph nodes is associated with a 50% reduction in 5-year survival. To identify a metastatic gene set based on DNA copy number abnormalities (CNAs) of differentially expressed genes, we compared DN
Externí odkaz: https://doaj.org/article/3a4e880dc86d46dfa2eaa1a7d5c369bc
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3
Data from Tumor and Salivary Matrix Metalloproteinase Levels Are Strong Diagnostic Markers of Oral Squamous Cell Carcinoma
Autor: Chu Chen, Stephen M. Schwartz, Neal D. Futran, Melissa P. Upton, Eduardo Méndez, Pawadee Lohavanichbutr, John R. Houck, Marni Stott-Miller
Background: The matrix metalloproteinases (MMP) cause degradation of the extracellular matrix and basement membranes, and thus may play a key role in cancer development.Methods: In our search for biomarkers for oral squamous cell carcinomas (OSCC), w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f17be9cb6efc447fbde794b3ca69b5b
https://doi.org/10.1158/1055-9965.c.6514998.v1
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10
Nested case–control study of telomere length and lung cancer risk among heavy smokers in the β-Carotene and Retinol Efficacy Trial
Autor: Gary E. Goodman, Mark D. Thornquist, Laurie Grieshober, Jennifer A. Doherty, Jean de Dieu Tapsoba, John R. Houck, Matt J. Barnett, Chu Chen, Ching-Yun Wang
Publikováno v: British Journal of Cancer
Background Telomeres protect cells from genomic instability. We examined telomere length and lung cancer risk prospectively in heavy smokers. Methods In a nested case–control study with 709 cases and 1313 controls, conditional logistic regression w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9646453080b8140d382c7e3f27dd3b9e
https://doi.org/10.1038/s41416-018-0075-0
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