Zobrazeno 1 - 10
of 334
pro vyhledávání: '"John R G, Challis"'
Autor:
Isabel Fortier, Claudio Delrieux, Shrankhala Tewari, Ashley Wazana, Laurent Briollais, Sandra T. Davidge, Dan Goldowitz, Ayesha Kareem, John R. G. Challis, Kristin L. Connor, Ayah Abdul-Hussein, Julie Bergeron, Pablo A. Nepomnaschy
Publikováno v:
Journal of developmental origins of health and disease. 12(3)
The Developmental Origins of Health and Disease (DOHaD) framework aims to understand how environmental exposures in early life shape lifecycle health. Our understanding and the ability to prevent poor health outcomes and enrich for resiliency remain
Autor:
Alan D. Bocking, Gregory B. Gloor, Elizabeth Asztalos, Deborah Money, Shannon Seney, Gregor Reid, John R. G. Challis, Siwen Yang
Publikováno v:
Nutrients
Volume 12
Issue 2
Microbiology & Immunology Publications
Nutrients, Vol 12, Iss 2, p 368 (2020)
Volume 12
Issue 2
Microbiology & Immunology Publications
Nutrients, Vol 12, Iss 2, p 368 (2020)
Spontaneous preterm birth is associated with vaginal microbial dysbiosis. As certain strains of lactobacilli help restore homeostasis in non-pregnant women, the goal was to determine the effect of Lactobacillus rhamnosus GR-1 and Lactobacillus reuter
Publikováno v:
Endocrinology ISBN: 9783030035945
Endocrinology
Endocrinology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42bd23386e314b3aa6314cf76eaccd5f
https://doi.org/10.1007/978-3-030-14782-2_20
https://doi.org/10.1007/978-3-030-14782-2_20
Publikováno v:
Reproductive Sciences. 25:239-245
Preterm birth occurs in 9% to 13% of all human pregnancies and accounts for 80% of all neonatal morbidities and mortalities. Approximately 40% of all preterm births are idiopathic and about half are associated with infection and/or an activated infla
Publikováno v:
Reproductive sciences (Thousand Oaks, Calif.). 25(2)
Preterm birth occurs in 9% to 13% of all human pregnancies and accounts for 80% of all neonatal morbidities and mortalities. Approximately 40% of all preterm births are idiopathic and about half are associated with infection and/or an activated infla
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 99:E2226-E2233
Context:Synthetic glucocorticoids (sGCs) are routinely given to women with threatened preterm labor and have been linked to fetal growth restriction and developmental programming. Reductions in fetal growth are likely to be mediated by placental dysf
Autor:
Marina Gagliardi de Assumpcao, Margarida Y.Y. Lei, John R. G. Challis, Carla Janzen, Gautam Chaudhuri, Suvajit Sen
Publikováno v:
The Journal of Clinical Endocrinology and Metabolism
Context: Biochemical weakening of the amnion is a major factor preceding preterm premature rupture of membranes (PPROMs), leading to preterm birth. Activation of matrix metalloproteinases (MMPs) is known to play a key role in collagen degradation of
Autor:
Ning Xie, Yunqing Li, Xuesen Dong, Oksana Shynlova, Martin E. Gleave, Stephanie Lam, Stephen J. Lye, John R. G. Challis, Liangliang Liu, Celeste Yu
Publikováno v:
Molecular Endocrinology. 26:1370-1379
Progesterone (P4), acting through its receptor (PR), is essential for the maintenance of pregnancy. P4 acts by suppressing uterine contractility and the expression of contraction-associated proteins (CAP) such as connexin 43 (Cx43). P4 levels must be
Autor:
John P. Newnham, John R. G. Challis, Shaofu Li, Ilias Nitsos, Timothy J. M. Moss, Thorsten Braun, Graeme R. Polglase
Publikováno v:
Reproductive Sciences. 19:260-270
We determined the effects of prenatal dexamethasone administration in early gestation on development of the hypothalamic-pituitary-adrenal (HPA) axis up to 7 months of postnatal age with measurements of hormone levels and gene expression. Plasma adre
Autor:
Xuesen Dong, Martin E. Gleave, Stephen J. Lye, Ning Xie, Liangliang Liu, John R. G. Challis, Paul S. Rennie
Publikováno v:
Molecular Endocrinology. 25:1197-1210
Originally identified as essential pre-mRNA splicing factors, non-POU-domain-containing, octamer binding protein (p54nrb) and PTB-associated RNA splicing factor (PSF) are also steroid receptor corepressors. The mechanisms by which p54nrb and PSF regu