Zobrazeno 1 - 9
of 9
pro vyhledávání: '"John R Dickson"'
Autor:
Ayush Noori, Colin Magdamo, Xiao Liu, Tanish Tyagi, Zhaozhi Li, Akhil Kondepudi, Haitham Alabsi, Emily Rudmann, Douglas Wilcox, Laura Brenner, Gregory K Robbins, Lidia Moura, Sahar Zafar, Nicole M Benson, John Hsu, John R Dickson, Alberto Serrano-Pozo, Bradley T Hyman, Deborah Blacker, M Brandon Westover, Shibani S Mukerji, Sudeshna Das
Publikováno v:
Journal of Medical Internet Research, Vol 24, Iss 8, p e40384 (2022)
BackgroundElectronic health records (EHRs) with large sample sizes and rich information offer great potential for dementia research, but current methods of phenotyping cognitive status are not scalable. ObjectiveThe aim of this study was to evaluate
Externí odkaz:
https://doaj.org/article/0a175401157e49f1a9a96ecde69cc1ca
Publikováno v:
Brain Communications. 5
Nucleoporin 98 is a nuclear pore complex component that is mislocalized in Alzheimer’s disease and the alteration in nucleoporin 98 has been attributed to tau. In order to determine if nucleoporin 98 mislocalization is a general feature of tauopath
Publikováno v:
Journal of Neuropathology and Experimental Neurology
Abnormal protein accumulation and mislocalization is a general hallmark of Alzheimer disease. Recent data suggest nucleocytoplasmic transport may be compromised by tau in Alzheimer disease. In this context, we have examined the RNA polymerase II subu
Autor:
Rosalyn M. Sulyanto, Clifford J. Beall, Martin B. Berger, Christopher P. Goodell, Stephanie Koo, Fiorella Candamo, John R. Dickson, Misun Kang, Sunita P. Ho, Man Wai Ng, Shahr B. Hashmi, Eugene J. Leys, Ann L. Griffen
Publikováno v:
JADA Foundational Science. 1:100004
Autor:
Yang Liu, Suxin Zheng, Eleanor Peacey, Christine P. Donahue, Michael S. Wolfe, Gabriele Varani, John R. Dickson
Publikováno v:
Journal of Medicinal Chemistry. 52:6523-6526
A series of mitoxantrone (MTX) analogues have been designed, synthesized, and evaluated for binding to and stabilizing a stem-loop structure that serves as a splicing regulatory element in the pre-mRNA of tau, which is involved in Alzheimer's and oth
Publikováno v:
Dickson, J R, Kruse, C, Montagna, D R, Finsen, B & Wolfe, M S 2013, ' Alternative polyadenylation and miR-34 family members regulate tau expression ', Journal of Neurochemistry, vol. 127, no. 6, pp. 739-749 . https://doi.org/10.1111/jnc.12437
Tau pathologically aggregates in Alzheimer's disease, and evidence suggests that reducing tau expression may be safe and beneficial for the prevention or treatment of this disease. We sought to examine the role of the 3′-untranslated region (3′-U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146ae4def0b3507fe15b1fdc383c9d15
https://europepmc.org/articles/PMC3859707/
https://europepmc.org/articles/PMC3859707/
Autor:
John R. Dickson, Dennis W. Brinkman
Publikováno v:
Environmental sciencetechnology. 29(1)
Used oils are an excellent example of a high-volume recyclable commodity that can be turned from a waste into valuable products. Debate concerning the degree of hazard posed by improper management of used oils relates to the typical contaminants one
Publikováno v:
Environmental sciencetechnology. 29(1)
Approximately 850 000 L of used oil contaminated with polychlorinated biphenyls was processed through a full-scale re-refinery using a vacuum distillation/ hydrotreatmenttechnology. The catalytic reaction with hydrogen not only destroyed the PCBs but
Publikováno v:
Seminars in Arthritis and Rheumatism. 18:247-251
G AMMA HEAVY CHAIN disease (7HCD). is characterized by the presence of incomplete immunoglobulin heavy chains in serum and/or urine’; although often described as a lymphoproliferative disorder, it has a wide variety of clinical and pathologic featu