Zobrazeno 1 - 10
of 164
pro vyhledávání: '"John R, Matyas"'
Autor:
Manmeet S. Dhiman, Taylor J. Bader, Dragana Ponjevic, Paul T. Salo, David A. Hart, Ganesh Swamy, John R. Matyas, Neil A. Duncan
Publikováno v:
JOR Spine, Vol 7, Iss 3, Pp n/a-n/a (2024)
Abstract Introduction Degenerative disc disease (DDD) is accompanied by structural changes in the intervertebral discs (IVD). Extra‐cellular matrix degradation of the annulus fibrosus (AF) has been linked with degeneration of the IVD. Collagen is a
Externí odkaz:
https://doaj.org/article/436a730e48364e9ca1ce1b9893c9a13f
Autor:
Roman J. Krawetz, Yiru Elizabeth Wu, Karri L. Bertram, Anchita Shonak, Anand O. Masson, Guomin Ren, Catherine Leonard, Mohit Kapoor, John R. Matyas, Paul T. Salo
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-16 (2022)
Abstract Aggrecan is a critical component of the extracellular matrix of all cartilages. One of the early hallmarks of osteoarthritis (OA) is the loss of aggrecan from articular cartilage followed by degeneration of the tissue. Mesenchymal progenitor
Externí odkaz:
https://doaj.org/article/39a5e62d9d7a4f7d9e4e3ea507b01586
Autor:
Charlie H. T. Kwok, Yuta Kohro, Michael Mousseau, Melissa S. O’Brien, John R. Matyas, Jason J. McDougall, Tuan Trang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Increased afferent input resulting from painful injury augments the activity of central nociceptive circuits via both neuron-neuron and neuron-glia interactions. Microglia, resident immune cells of the central nervous system (CNS), play a crucial rol
Externí odkaz:
https://doaj.org/article/f6a3eca28d1349de9516c2efbdc47656
Autor:
Malcolm Eaton, Alastair H Davies, Jay Devine, Xiang Zhao, David G Simmons, Elín Maríusdóttir, David R C Natale, John R Matyas, Elizabeth A Bering, Matthew L Workentine, Benedikt Hallgrimsson, James C Cross
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0226735 (2020)
The major milestones in mouse placental development are well described, but our understanding is limited to how the placenta can adapt to damage or changes in the environment. By using stereology and expression of cell cycle markers, we found that th
Externí odkaz:
https://doaj.org/article/ac82a34bf0e345a49d72986bccb0cdc8
Autor:
Massieh Moayedi, Abigail J. D’Souza, Sarah F. Rosen, Helena Fetter Filippini, Anastassia Dokova, Vassilia Michailidis, Igor Vukobradovic, Toni-Lee Sterley, Paul D. Whissell, Wai-Jane Virginia Lee, John R. Matyas, Maian Christine Pham, Hantao Zhang, Jeff Biernaskie, Chereen Collymore, David N. Dubins, Ingita Patel, Loren J. Martin, Chulmin Cho, Hayley Crawhall-Duk, Irene Lecker, Jo Anne Stratton, Hendrik W. Steenland, Robert P. Bonin, Jeffrey S. Mogil, Jaideep S. Bains, Ann M. Flenniken, Jerry Li, Alexandr Bezginov, Maham Zain, Megan Valencia
Publikováno v:
Pain
Supplemental Digital Content is Available in the Text. Cage-lid hanging behavior is impaired by sustained pain in mice and can be used as an ethologically valid and translationally relevant pain outcome measure.
The development of new analgesic
The development of new analgesic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f962ef38ca883f16a41397a4208643
http://europepmc.org/articles/PMC8054539
http://europepmc.org/articles/PMC8054539
Autor:
Nicholas G. Jendzjowsky, Elaine Dumoulin, Michelle S Malig, Alex Chee, John R. Matyas, Elaine de Heuvel, Curtis Dumonceaux, Alain Tremblay, Austin Laing, Margaret M. Kelly, Richard Leigh
Publikováno v:
The European respiratory journal. 59(1)
Rationale Bronchial thermoplasty is a mechanical therapeutic intervention that has been advocated as an effective treatment option for severe asthma. The mechanism is promoted as being related to the attenuation of airway smooth muscle which has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c33cdf88a77a4f6f3fd4a305938d26
https://pubmed.ncbi.nlm.nih.gov/34972685
https://pubmed.ncbi.nlm.nih.gov/34972685
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 3, p e0248104 (2021)
PLoS ONE, Vol 16, Iss 3, p e0248104 (2021)
Back pain and intervertebral disc degeneration are prevalent, costly, and widely treated by manual therapies, yet the underlying causes of these diseases are indeterminate as are the scientific bases for such treatments. The present studies character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9198df5aabcce043bebf9d8424fd20ee
http://europepmc.org/articles/PMC7987143
http://europepmc.org/articles/PMC7987143
Autor:
Jaymi T. Taiani, Roman J. Krawetz, Akihiro Yamashita, Yves Pauchard, Helen R. Buie, Dragana Ponjevic, Steven K. Boyd, Derrick E. Rancourt, John R. Matyas
Publikováno v:
Cell Transplantation, Vol 22 (2013)
Embryonic stem (ES) cells are a uniquely self-renewing, pluripotent population of cells that must be differentiated before being useful for cell therapy. Since most studies utilize subcutaneous implantation to test the in vivo functionality of ES cel
Externí odkaz:
https://doaj.org/article/115f0a8df3c6490a87656a6879932459
Publikováno v:
Connective tissue research. 62(5)
Osteoarthritis is a common chronic disease of joints characterized by degenerative changes of articular cartilage. An early diagnosis of osteoarthritis may be possible when imaging excised tissue for research in situ at the cellular-molecular scale.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f9e9abbf02c2436c502477eae23dcd
https://pubmed.ncbi.nlm.nih.gov/32814448
https://pubmed.ncbi.nlm.nih.gov/32814448
Autor:
Elín Maríusdóttir, Benedikt Hallgrímsson, Alastair H. Davies, Matthew L. Workentine, James C. Cross, Elizabeth A. Bering, John R. Matyas, Jay Devine, Malcolm Eaton, David R. C. Natale, David G. Simmons, Xiang Zhao
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0226735 (2020)
PLoS ONE
PLoS ONE
The major milestones in mouse placental development are well described, but our understanding is limited to how the placenta can adapt to damage or changes in the environment. By using stereology and expression of cell cycle markers, we found that th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d3a57150210e63fa7337751d4a3f2b
https://doaj.org/article/ac82a34bf0e345a49d72986bccb0cdc8
https://doaj.org/article/ac82a34bf0e345a49d72986bccb0cdc8