Zobrazeno 1 - 10
of 90
pro vyhledávání: '"John R, Arrand"'
Autor:
Hannah E. Bridgewater, Kathryn L. Date, John D. O’Neil, Chunfang Hu, John R. Arrand, Christopher W. Dawson, Lawrence S. Young
Publikováno v:
Pathogens, Vol 9, Iss 7, p 594 (2020)
The Epstein-Barr virus (EBV)-encoded nuclear antigen 1 (EBNA1) protein is expressed in all virus-associated malignancies, where it performs an essential role in the maintenance, replication and transcription of the EBV genome. In recent years, it has
Externí odkaz:
https://doaj.org/article/ce316e345ad54c2eaf0a68eb6202025c
Autor:
Chunfang Hu, Wenbin Wei, Xiaoyi Chen, Ciaran B Woodman, Yunhong Yao, John M Nicholls, Irène Joab, Sim K Sihota, Jian-Yong Shao, K Dalia Derkaoui, Aicha Amari, Stephanie L Maloney, Andrew I Bell, Paul G Murray, Christopher W Dawson, Lawrence S Young, John R Arrand
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41055 (2012)
Previous studies have reported that the tumour cells of nasopharyngeal carcinoma (NPC) exhibit recurrent chromosome abnormalities. These genetic changes are broadly assumed to lead to changes in gene expression which are important for the pathogenesi
Externí odkaz:
https://doaj.org/article/8f662a7d54aa4ae18f6d06c5d45f7c40
Autor:
Daniel H. Palmer, John R. Arrand, Darren Barton, Wing Kin Syn, Nicholas D. James, Taha Elmetwali, Joseph J. Sacco, Puthen V. Jithesh, Richard M.D. Greensmith, D. Ross Sibson, Jawaher Ansari, Syed A. Hussain, Vijay Aachi, Bryony H. Lloyd
Publikováno v:
International Journal of Oncology
Despite advances in management, bladder cancer remains a major cause of cancer related complications. Characterisation of gene expression patterns in bladder cancer allows the identification of pathways involved in its pathogenesis, and may stimulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f54b29e9a1881555e2b83678933433b
https://doi.org/10.3892/ijo.2017.3893
https://doi.org/10.3892/ijo.2017.3893
Publikováno v:
European journal of medical genetics. 61(4)
The genetic association between autism spectrum disorder (ASD) and psychotic disorders such as schizophrenia is complicated and mirrors the clinical overlap between these conditions to some degree. However, no studies to date have examined the geneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c529a8b511983a66e13eeff75fa477
https://pubmed.ncbi.nlm.nih.gov/29225144
https://pubmed.ncbi.nlm.nih.gov/29225144
Autor:
John R. Arrand, Christopher W. Dawson, Sonia Pinheiro-Maia, Rebecca J. Port, Chunfang Hu, Lawrence S. Young, Wenbin Wei
Publikováno v:
The Journal of Pathology. 231:367-377
Nasopharyngeal carcinoma (NPC) is a cancer common in southern China and South East Asia that is causally linked to Epstein-Barr virus (EBV) infection. Here, we demonstrate that NPC displays frequent dysregulation of the Hedgehog (HH) pathway, a pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e05183cabe24178662c7b7fb0a815995
https://doi.org/10.1002/path.4245
https://doi.org/10.1002/path.4245
Autor:
Zheng-yun Zhao, Joseph S. Vyle, James H. R. Tucker, John R. Arrand, Jean-Louis H. A. Duprey, Marie San
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:129-132
Single nucleotide polymorphisms within a sequence of a gene associated with prostate cancer were identified using oligodeoxynucleotide probe sequences bearing internal anthracene fluorophores proximal to the SNP site. Depending upon the nature of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d09ba9eeaba115ba1ac3322594743985
https://doi.org/10.1016/j.bmcl.2011.11.053
https://doi.org/10.1016/j.bmcl.2011.11.053
Autor:
Michael Hummel, Dido Lenze, Michael Kuo, Paul Murray, Stefan Bentink, Dieter Kube, John R. Arrand, Rainer Spang, Lorenz Trümper, Alexandra Schrader, Martina Vockerodt
Publikováno v:
International Journal of Cancer. 131:E348-E361
Gene expression profiling has recently enabled the reclassification of aggressive non-Hodgkin lymphomas (aNHL) into distinct subgroups. In Burkitt lymphoma (BL) aberrant c-Myc activity results from IG-MYC translocations. However, MYC aberrations are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2715f46137358572f0201747ba66a5bb
https://doi.org/10.1002/ijc.26423
https://doi.org/10.1002/ijc.26423
Autor:
Robert Valentine, John R. Arrand, Kathryn L Date, Marilyn B. Chukwuma, Victoria H. J. Wood, Christopher W. Dawson, Lawrence S. Young, Thomas J Owen, John D. O'Neil
Publikováno v:
Journal of General Virology. 89:2833-2842
The Epstein–Barr virus (EBV)-encoded EBNA1 protein is expressed in all virus-associated tumours, including nasopharyngeal carcinoma (NPC), where it plays an essential role in EBV genome maintenance, replication and transcription. Previous studies s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1a10b4f84c59123c6adb60cf237142
https://doi.org/10.1099/vir.0.2008/003392-0
https://doi.org/10.1099/vir.0.2008/003392-0
Autor:
Dieter Kube, John Gordon, Marilyn B. Chukwuma, Ciaran B J Woodman, John R. Arrand, Paul Murray, Martina Vockerodt, Lawrence S. Young, Michael Kuo, Susan Morgan, Wenbin Wei
Publikováno v:
The Journal of Pathology. 216:83-92
Although the latent membrane protein-1 (LMP1) of the Epstein-Barr virus (EBV) is believed to be important for the transformation of germinal centre (GC) B cells, the precise contribution of this viral oncogene to lymphoma development is poorly unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9d92c6b41512086db87f86ffd0963d2
https://doi.org/10.1002/path.2384
https://doi.org/10.1002/path.2384
Autor:
Alan B. Rickinson, Simon J. Watson, Samantha Correia, Martin J. Allday, Craig Corton, Anne L. Palser, Mohammed M. Ba Abdullah, Paul J. Farrell, Lawrence S. Young, Paul Kellam, Paul Murray, John R. Arrand, Nicholas E. Grayson, Robert E. White, Matthew Cotten
Publikováno v:
Journal of Virology
Epstein-Barr virus (EBV) infects most of the world's population and is causally associated with several human cancers, but little is known about how EBV genetic variation might influence infection or EBV-associated disease. There are currently no pub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f45977d1482b3b146fcc152e5349f2b
https://eprints.gla.ac.uk/196561/1/196561.pdf
https://eprints.gla.ac.uk/196561/1/196561.pdf
