Zobrazeno 1 - 10
of 13
pro vyhledávání: '"John Pyles"'
Autor:
Robert Colby Layton, Andrew Gigliotti, Penny Armijo, Leslie Myers, Jennifer Knight, Nathaniel Donart, John Pyles, Sarah Vaughan, Jennifer Plourde, Ndingsa Fomukong, Kevin S Harrod, Peng Gao, Frederick Koster
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20641 (2011)
Pre-pandemic development of an inactivated, split-virion avian influenza vaccine is challenged by the lack of pre-existing immunity and the reduced immunogenicity of some H5 hemagglutinins compared to that of seasonal influenza vaccines. Identificati
Externí odkaz:
https://doaj.org/article/828c774bd1eb4852b7567f91247b9af6
Advances in modern artificial intelligence (AI) have inspired a paradigm shift in human neuroscience, yielding large-scale functional magnetic resonance imaging (fMRI) datasets that provide high-resolution brain responses to tens of thousands of natu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89cff1708e9683a848e7ef1552cb2c54
https://doi.org/10.1101/2022.01.31.478431
https://doi.org/10.1101/2022.01.31.478431
Autor:
R. Colby Layton, Peng Gao, Nathaniel Donart, Alan S. Perelson, Stephanie Forrest, Catherine A. A. Beauchemin, Kevin S. Harrod, Drew Levin, Hugh D. Mitchell, Jennifer L. Tipper, John Pyles, Jennifer Knight, Frederick Koster
Publikováno v:
Journal of Virology. 85:1125-1135
The pathogenicity and transmission of influenza A viruses are likely determined in part by replication efficiency in human cells, which is the net effect of complex virus-host interactions. H5N1 avian, H1N1 seasonal, and H1N1 2009 pandemic influenza
Autor:
Frederick Koster, Zemmie Pollock, John Pyles, Nikolai Petrovsky, Jennifer Knight, Peng Gao, Andrew P. Gigliotti, R. Colby Layton, Nathaniel Donart, Kevin S. Harrod
The reduced immunogenicity of the H5 hemagglutinin (HA), compared to seasonal HA serotypes, has stimulated searches for effective adjuvants to improve H5 vaccine efficacy. This study examined the immunogenicity and protective efficacy in ferrets immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a10e7fa30d73e0e7ccd5a22909157845
https://europepmc.org/articles/PMC3156374/
https://europepmc.org/articles/PMC3156374/
Autor:
Kevin S. Harrod, Jesse Van Westrienen, Lance Price, Hugh D. Mitchell, Christopher E. Hart, Kathleen Maxwell, John Pyles
Publikováno v:
B66. REGULATING GENE EXPRESSION: MI-RNA, GROWTH FACTORS, ETC..
Autor:
Robert C. Layton, Kevin S. Harrod, John Pyles, Jennifer R. Plourde, Zemmie Pollock, Sarah E. Vaughan, Zachary S. Karim, Andrew P. Gigliotti
Publikováno v:
A54. HOST DEFENSE MECHANISMS AGAINST VIRAL RESPIRATORY INFECTIONS.
Autor:
John Pyles, Donn C. Young, Pravin T. P. Kaumaya, Naveen Dakappagari, Robin Parihar, William E. Carson
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 170(8)
Immunotherapeutic approaches to cancer should focus on novel undertakings that modulate immune responses by synergistic enhancement of antitumor immunological parameters. Cancer vaccines should preferably be composed of multiple defined tumor Ag-spec
Publikováno v:
Peptides: The Wave of the Future ISBN: 9789401039055
HER-2, a member of the epidermal growth factor receptor family is overexpressed in 25–30% of breast, ovarian and colon cancers. HER-2 overexpression is associated with poor prognosis and resistance to chemo- and hormonal therapies. We recently repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::246e1b40cf78cf212f9ab8b60f93bca4
https://doi.org/10.1007/978-94-010-0464-0_473
https://doi.org/10.1007/978-94-010-0464-0_473
Publikováno v:
Peptides: The Wave of the Future ISBN: 9789401039055
Human Epidermal Growth Factor Receptor, HER-2 is a tumor-associated antigen overexpressed in many human malignancies. Monoclonal antibodies targeting HER-2 were shown to inhibit tumor growth both in animal models and human clinical trials. In additio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad11a49f76f319f6022ffe92f08c48f4
https://doi.org/10.1007/978-94-010-0464-0_469
https://doi.org/10.1007/978-94-010-0464-0_469
Autor:
Sarah Vaughan, Heather Stout-Delgado, Zemmie Pollock, Jennifer Plourde, John Pyles, Kevin Harrod
Publikováno v:
The Journal of Immunology. 190:123.18-123.18
Highly pathogenic avian influenza (HPAI) has an approximate 60% fatality rate in humans. In the United States, a vaccine for HPAI has been manufactured and stockpiled using FDA approved methods for seasonal vaccines. Compared to seasonal vaccines, th