Zobrazeno 1 - 10
of 19
pro vyhledávání: '"John Postlethwait"'
Autor:
Barbara Klotz, Susanne Kneitz, Yuan Lu, William Boswell, John Postlethwait, Wesley Warren, Ronald B. Walter, Manfred Schartl
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 7, Pp 2267-2276 (2019)
Small aquarium fish models provide useful systems not only for a better understanding of the molecular basis of many human diseases, but also for first-line screening to identify new drug candidates. For testing new chemical substances, current strat
Externí odkaz:
https://doaj.org/article/36d68abce2a94c45b919633961964922
Autor:
Qiaowei Pan, Romain Feron, Elodie Jouanno, Hugo Darras, Amaury Herpin, Ben Koop, Eric Rondeau, Frederick W Goetz, Wesley A Larson, Louis Bernatchez, Mike Tringali, Stephen S Curran, Eric Saillant, Gael PJ Denys, Frank A von Hippel, Songlin Chen, J Andrés López, Hugo Verreycken, Konrad Ocalewicz, Rene Guyomard, Camille Eche, Jerome Lluch, Celine Roques, Hongxia Hu, Roger Tabor, Patrick DeHaan, Krista M Nichols, Laurent Journot, Hugues Parrinello, Christophe Klopp, Elena A Interesova, Vladimir Trifonov, Manfred Schartl, John Postlethwait, Yann Guiguen
Publikováno v:
eLife, Vol 10 (2021)
The understanding of the evolution of variable sex determination mechanisms across taxa requires comparative studies among closely related species. Following the fate of a known master sex-determining gene, we traced the evolution of sex determinatio
Externí odkaz:
https://doaj.org/article/600f952d9d9246a19aec4256aff0094f
Autor:
Iliana Bista, Shane A. McCarthy, Jonathan Wood, Zemin Ning, H. William Detrich III, Thomas Desvignes, John Postlethwait, William Chow, Kerstin Howe, James Torrance, Michelle Smith, Karen Oliver, Vertebrate Genomes Project Consortium, Eric A. Miska, Richard Durbin
Publikováno v:
Wellcome Open Research, Vol 5 (2020)
We present a genome assembly for Cottoperca gobio (channel bull blenny, (Günther, 1861)); Chordata; Actinopterygii (ray-finned fishes), a temperate water outgroup for Antarctic Notothenioids. The size of the genome assembly is 609 megabases, with th
Externí odkaz:
https://doaj.org/article/ec7cc13043b04db8a3599ea03bfc8239
Autor:
Qiaowei Pan, Romain Feron, Ayaka Yano, René Guyomard, Elodie Jouanno, Estelle Vigouroux, Ming Wen, Jean-Mickaël Busnel, Julien Bobe, Jean-Paul Concordet, Hugues Parrinello, Laurent Journot, Christophe Klopp, Jérôme Lluch, Céline Roques, John Postlethwait, Manfred Schartl, Amaury Herpin, Yann Guiguen
Publikováno v:
PLoS Genetics, Vol 15, Iss 8, p e1008013 (2019)
Teleost fishes, thanks to their rapid evolution of sex determination mechanisms, provide remarkable opportunities to study the formation of sex chromosomes and the mechanisms driving the birth of new master sex determining (MSD) genes. However, the e
Externí odkaz:
https://doaj.org/article/8916fa475abd4234b731a72bf7d8a6a1
Autor:
Yuan Lu, Mikki Boswell, William Boswell, Susanne Kneitz, Barbara Klotz, Markita Savage, Raquel Salinas, Rebecca Marks, Janine Regneri, John Postlethwait, Wesley C Warren, Manfred Schartl, Ronald Walter
Publikováno v:
PLoS Genetics, Vol 14, Iss 12, p e1007875 (2018)
Understanding the genetic mechanisms underlying segregation of phenotypic variation through successive generations is important for understanding physiological changes and disease risk. Tracing the etiology of variation in gene expression enables ide
Externí odkaz:
https://doaj.org/article/0df5abbca03940fe8196b5f55ea64255
Autor:
Amjad Askary, Joanna Smeeton, Sandeep Paul, Simone Schindler, Ingo Braasch, Nicholas A Ellis, John Postlethwait, Craig T Miller, J Gage Crump
Publikováno v:
eLife, Vol 5 (2016)
Synovial joints are the lubricated connections between the bones of our body that are commonly affected in arthritis. It is assumed that synovial joints first evolved as vertebrates came to land, with ray-finned fishes lacking lubricated joints. Here
Externí odkaz:
https://doaj.org/article/c651b08c8d3d4f3db8e1df87055b5f3b
Autor:
Manfred Schartl, Yingjia Shen, Katja Maurus, Ron Walter, Chad Tomlinson, Richard K Wilson, John Postlethwait, Wesley C Warren
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143057 (2015)
The incidence of malignant melanoma continues to increase each year with poor prognosis for survival in many relapse cases. To reverse this trend, whole body response measures are needed to discover collaborative paths to primary and secondary malign
Externí odkaz:
https://doaj.org/article/f51e3a85a69e4ca88a85791d134649c9
Autor:
Lachlan Baer, Karissa Barthelson, John Postlethwait, David Adelson, Stephen Pederson, Michael Lardelli
Publikováno v:
bioRxiv
In comparisons between mutant and wild-type genotypes, transcriptome analysis can reveal the direct impacts of a mutation, together with the homeostatic responses of the biological system. Recent studies have highlighted that, when homozygous mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4d28b7c2ecf7e6967b413c6737e851
https://europepmc.org/articles/PMC10028786/
https://europepmc.org/articles/PMC10028786/
Autor:
Yi-Lin, Yan, Thomas, Desvignes, Ruth, Bremiller, Catherine, Wilson, Danielle, Dillon, Samantha, High, Bruce, Draper, Charles Loren, Buck, John, Postlethwait
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 246(11)
Aberrant signaling between germ cells and somatic cells can lead to reproductive disease and depends on diffusible signals, including transforming growth factor-beta (TGFB) -family proteins. The TGFB-family protein Gsdf (gonadal soma derived factor)