Zobrazeno 1 - 10
of 16
pro vyhledávání: '"John Polzer"'
Autor:
Michael McCleod, David R. Spigel, Oday Hamid, R. Waide Weaver, Ravi Salgia, John Polzer, John R. Stille, Stephanie Roberson, Amy Flynt
Publikováno v:
Lung Cancer. 105:7-13
Objectives This multicenter, open-label, randomized phase II study evaluated the efficacy and safety of LY2510924 (LY) added to first‐line standard of care (SOC) chemotherapy for extensive-disease small cell lung cancer (ED-SCLC) and explored the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c6b5bc6e6936b3ae1d6b443c1b054c
https://doi.org/10.1016/j.lungcan.2016.12.020
https://doi.org/10.1016/j.lungcan.2016.12.020
Autor:
Patrick Nadolny, Elena Gribkova, David Knepper, Brett Wilson, Alun Bedding, Christian Fenske, Joanne Benedict, Andy Lawton, Jennifer Neumann, John Polzer
Publikováno v:
Therapeutic Innovation & Regulatory Science. 50:15-21
Data quality issues in clinical trials can be caused by a variety of behaviors including fraud, misconduct, intentional or unintentional noncompliance, and significant carelessness. Regardless of how these behaviors are defined, they may compromise t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e893b32422ba083bb7bb42d7d86b1c8
https://doi.org/10.1177/2168479015620248
https://doi.org/10.1177/2168479015620248
Publikováno v:
The Social Science Journal. 51:652-658
Prosecutorial misconduct is not a rare event, but it often goes undetected, unreported, or no action is taken by the criminal justice system. However, when one Texas prosecutor, Ken Anderson, served jail time for wrongfully prosecuting an innocent ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf19e0b840f3e83a50744aa342c2acbc
https://doi.org/10.1016/j.soscij.2014.05.007
https://doi.org/10.1016/j.soscij.2014.05.007
Autor:
John R. Stille, Eyas Raddad, John Polzer, Matthew D. Galsky, Stephanie Roberson, Paul Conkling, Nicholas J. Vogelzang, Mansoor N. Saleh, Donald Thornton
Publikováno v:
Clinical Cancer Research. 20:3581-3588
Purpose: Overexpression of C-X-C motif receptor 4 (CXCR4) is implicated in tumor progression. LY2510924 is a peptide antagonist, which blocks stromal cell–derived factor-1 (SDF1) from CXCR4 binding. Experimental Design: This phase I study included
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83d8c5e575a850e1b8dea9e4527a37b
https://doi.org/10.1158/1078-0432.ccr-13-2686
https://doi.org/10.1158/1078-0432.ccr-13-2686
Publikováno v:
The Social Science Journal. 50:374-380
The West Memphis Three case captivated the country over the past two decades for many reasons. The crime, a triple homicide of children, the lack of evidence and coerced confessions, the verdicts, and ultimately, the way the three men were released c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e78e4ff8b999fe9ce52272bfd7ed629
https://doi.org/10.1016/j.soscij.2013.03.004
https://doi.org/10.1016/j.soscij.2013.03.004
Autor:
Andrea De Gaetano, William H. Landschulz, John Polzer, Jeffrey W. Miller, Eyas Abu-Raddad, Jolene K. Berg, Joel C Scherer, Joanne Sloan-Lancaster
Publikováno v:
Diabetes Care
OBJECTIVE Inflammation is associated with pancreatic β-cell apoptosis and reduced insulin sensitivity. Literature suggests that interleukin (IL)-1β may contribute to the pathogenesis of type 2 diabetes mellitus (T2DM). This study aimed to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c504ec3a3cc9cee002a99ddccf2f4d1f
https://doi.org/10.2337/dc12-1835
https://doi.org/10.2337/dc12-1835
Autor:
James A. Reeves, Amy Flynt, Oday Hamid, Stephanie Roberson, Edward J. Crane, John D. Hainsworth, John Polzer, Edward Arrowsmith, John R. Stille, Joseph R. Mace
Publikováno v:
Targeted oncology. 11(5)
The chemokine (C-X-C Motif) receptor 4 (CXCR4) and its ligand, stromal-cell derived factor-1 (SDF-1), are frequently overexpressed in a variety of solid tumors, and are believed to play important roles in the regulation of organ-specific metastasis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fcbb96354eb241f5becd255dbee45ac
https://pubmed.ncbi.nlm.nih.gov/27154357
https://pubmed.ncbi.nlm.nih.gov/27154357
Autor:
Paula T. Trzepacz, John Polzer, Nayan Acharya, Shuyu Zhang, Mark E. Bangs, Albert J. Allen, Sitra Tauscher-Wisniewski, Durisala Desaiah
Publikováno v:
Journal of the American Academy of Child & Adolescent Psychiatry. 47:209-218
Objective: The present work examined suicide-related events in acute, double-blind, and placebo- or active comparator-controlled trials with atomoxetine. Method: Fourteen trials in pediatric patients were included. Potential events were identified in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f0cbb737435e843f208e48cce9a582
https://doi.org/10.1097/chi.0b013e31815d88b2
https://doi.org/10.1097/chi.0b013e31815d88b2
Autor:
Patrizia A Cavazzoni, Nayan Acharya, Ross J. Baldessarini, Deborah N. D'Souza, John Polzer, David G Perahia, Amy S Rosen
Publikováno v:
Journal of Clinical Psychopharmacology. 26:587-594
BACKGROUND: Uncertainty regarding relationships of antidepressant treatment and suicidality encouraged systematic review of data on suicidal behaviors and ideation from Phase II and III clinical trials of duloxetine for major depressive disorder (MDD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d0056f935ab0f624d083b2b71bd0b0
https://doi.org/10.1097/01.jcp.0000246216.26400.db
https://doi.org/10.1097/01.jcp.0000246216.26400.db
Autor:
J. Carlson, P. Cavazzoni, Carrie A Young, Ludmila Kryzhanovskaya, Tamra E. Roddy, Dilip V. Jeste, John Polzer, Joe F Jansen
Publikováno v:
The Journal of Clinical Psychiatry. 67:933-945
Objective Olanzapine and other antipsychotics are not approved by the U.S. Food and Drug Administration to treat behavioral disturbances associated with dementia, but they are often prescribed to these patients. Although antipsychotics may be efficac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc79ade9c1ae6e001ee6e6f1834b537
https://doi.org/10.4088/jcp.v67n0610
https://doi.org/10.4088/jcp.v67n0610