Zobrazeno 1 - 10
of 233
pro vyhledávání: '"John Paul, Shen"'
Autor:
Abdelrahman Yousef, Mahmoud Yousef, Saikat Chowdhury, Kawther Abdilleh, Mark Knafl, Paul Edelkamp, Kristin Alfaro-Munoz, Ray Chacko, Jennifer Peterson, Brandon G. Smaglo, Robert A. Wolff, Shubham Pant, Michael S. Lee, Jason Willis, Michael Overman, Sudheer Doss, Lynn Matrisian, Mark W. Hurd, Rebecca Snyder, Matthew H. G. Katz, Huamin Wang, Anirban Maitra, John Paul Shen, Dan Zhao
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-13 (2024)
Abstract The relevance of KRAS mutation alleles to clinical outcome remains inconclusive in pancreatic adenocarcinoma (PDAC). We conducted a retrospective study of 803 patients with PDAC (42% with metastatic disease) at MD Anderson Cancer Center. Ove
Externí odkaz:
https://doaj.org/article/07e4c9e5f98d41abaef00dd9155ae1ad
Autor:
Fadl A. Zeineddine, Mohammad A. Zeineddine, Abdelrahman Yousef, Yue Gu, Saikat Chowdhury, Arvind Dasari, Ryan W. Huey, Benny Johnson, Bryan Kee, Michael S. Lee, Maria Pia Morelli, Van K. Morris, Michael J. Overman, Christine Parseghian, Kanwal Raghav, Jason Willis, Robert A. Wolff, Yoshikuni Kawaguchi, Jean-Nicolas Vauthey, Ryan Sun, Scott Kopetz, John Paul Shen
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-9 (2023)
Abstract Over the past two decades of successive clinical trials in metastatic colorectal cancer (CRC), the median overall survival of both control and experimental arms has steadily improved. However, the incremental change in survival for metastati
Externí odkaz:
https://doaj.org/article/7b9f437bc4574113bf04a302f7650255
Autor:
Shanmuga Venkatachalam, Harideep Nair, Ming Zeng, Cathy Shunwen Tan, Ole J. Mengshoel, John Paul Shen
Publikováno v:
Frontiers in Big Data, Vol 6 (2023)
Externí odkaz:
https://doaj.org/article/53e32fc399ed4d8f91d0664dc8ea4030
Autor:
Shanmuga Venkatachalam, Harideep Nair, Ming Zeng, Cathy Shunwen Tan, Ole J. Mengshoel, John Paul Shen
Publikováno v:
Frontiers in Big Data, Vol 5 (2022)
Human Activity Recognition (HAR) is a prominent application in mobile computing and Internet of Things (IoT) that aims to detect human activities based on multimodal sensor signals generated as a result of diverse body movements. Human physical activ
Externí odkaz:
https://doaj.org/article/e1e0d579f8914ad6b954f6bd8ae5a0ce
Autor:
Lihua Wang, Ergang Wang, Jorge Prado Balcazar, Zhenzhen Wu, Kun Xiang, Yi Wang, Qiang Huang, Marcos Negrete, Kai‐Yuan Chen, Wei Li, Yujie Fu, Anders Dohlman, Robert Mines, Liwen Zhang, Yoshihiko Kobayashi, Tianyi Chen, Guizhi Shi, John Paul Shen, Scott Kopetz, Purushothama Rao Tata, Victor Moreno, Charles Gersbach, Gregory Crawford, David Hsu, Emina Huang, Pengcheng Bu, Xiling Shen
Publikováno v:
Advanced Science, Vol 8, Iss 19, Pp n/a-n/a (2021)
Abstract Colorectal cancer (CRC) metastasizes mainly to the liver, which accounts for the majority of CRC‐related deaths. Here it is shown that metastatic cells undergo specific chromatin remodeling in the liver. Hepatic growth factor (HGF) induces
Externí odkaz:
https://doaj.org/article/d9e4ca4741b44963bbd7506d05a7e116
Autor:
Preeti Kanikarla Marie, Natalie W. Fowlkes, Vahid Afshar-Kharghan, Stephanie L. Martch, Alexey Sorokin, John Paul Shen, Van K. Morris, Arvind Dasari, Nancy You, Anil K. Sood, Michael J. Overman, Scott Kopetz, David George Menter
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Both platelets and the liver play important roles in the processes of coagulation and innate immunity. Platelet responses at the site of an injury are rapid; their immediate activation and structural changes minimize the loss of blood. The majority o
Externí odkaz:
https://doaj.org/article/d372e71f7a2f40a79c386cc5ab8f208d
Publikováno v:
Journal of Medical Case Reports, Vol 13, Iss 1, Pp 1-6 (2019)
Abstract Background Hemophagocytic lymphohistiocytosis is a rare hematological syndrome characterized by excessive and uncontrolled activation of the immune system. The often nonspecific nature of early symptoms and the potential for progression to m
Externí odkaz:
https://doaj.org/article/d73343be2baf4436a25595593bd1884b
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Informative pathways driving cancer pathogenesis and subtypes can be difficult to identify in the presence of many gene interactions irrelevant to cancer. Here, the authors describe an approach for cancer gene pathway analysis based on key molecular
Externí odkaz:
https://doaj.org/article/23364b3760004de1a37cb9eef7adaa17
Autor:
Van K. Morris, Michael J. Overman, Michael Lam, Christine M. Parseghian, Benny Johnson, Arvind Dasari, Kanwal Raghav, Bryan K. Kee, Ryan Huey, Robert A. Wolff, John Paul Shen, June Li, Isabel Zorrilla, Ching-Wei D. Tzeng, Hop S. Tran Cao, Yun Shin Chun, Timothy E. Newhook, Nicolas Vauthey, Dzifa Duose, Raja Luthra, Cara Haymaker, Scott Kopetz
Publikováno v:
Cancer Res Commun
Identification of circulating tumor DNA (ctDNA) following curative intent therapies is a surrogate for microscopic residual disease for patients with metastatic colorectal cancer (mCRC). Preclinically, in micrometastatic microsatellite stable (MSS) c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd32a40e422d9ad04c0373b193c33e1a
https://doi.org/10.1158/2767-9764.crc-22-0194
https://doi.org/10.1158/2767-9764.crc-22-0194
Autor:
Aditya More, Ichiaki Ito, Valsala Haridas, Saikat Chowdhury, Yue Gu, Princess Dickson, Natalie Fowlkes, John Paul Shen
Publikováno v:
Oncogene. 41:4159-4168
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8206c206b3c3f6911e3df7f346aa1786
https://doi.org/10.1038/s41388-022-02388-6
https://doi.org/10.1038/s41388-022-02388-6