Zobrazeno 1 - 10
of 194
pro vyhledávání: '"John Patterson"'
Autor:
Xiaoqing Li, Yunhai Bo, Qingping Zeng, Lei Diao, Stephanie Greene, John Patterson, Lu Liu, Fen Yang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background: ORIN1001, a first-in-class oral IRE1-α endoribonuclease inhibitor to block the activation of XBP1, is currently in clinical development for inhibiting tumor growth and enhancing the effect of chemical or targeted therapy. Early establish
Externí odkaz:
https://doaj.org/article/f807ce6e694648adacfed803dbdf3074
Autor:
Paresh Malhotra, David J Sharp, Yuchen Zhao, Michael David, David Sharp, Michael Fertleman, Lenny Naar, Sarah Daniels, Ramin Nilforooshan, Derk-Jan Dijk, Claire Norman, Greg Scott, Ian Williams, John Patterson, Neil Graham, David Wingfield, Mara Golemme, Melanie Dani, Sanara Raza, Lucia M Li, Sumit Dey, Eyal Soreq, Payam Barnaghi, Martina Del Giovane, Magdalena Kolanko, Ciro Della Monica, Helen Lai, Tong Wu, Megan E Parkinson, Danielle Wilson, Zaynab Ismail, Paul Freemont, Ravi Vaidyanathan, Tim Constandinou, Naomi Hassim, Mark Crook Rumsey, Emma Jane Mallas, Alina-Irina Serban, Alan Bannon, Shlomi Haar, Charalambos Hadjipanayi, Ghena Hammour, Bryan Hsieh, Adrien Rapeaux, Maowen Yin, Maria Lima, Maitreyee Wairagkar, Nan Fletcher-Lloyd, Hamed Haddadi, Valentinas Janeiko, Anna Joffe, Samaneh Kouchaki, Viktor Levine, Honglin Li, Amer Marzuki, Francesca Palermo, Mark Woodbridge, Alexander Capstick, Severin Skillman, Loren Cameron, Michael Crone, Kirsten Jensen, Anne Skeldon, Kevin Wells, Ullrich Bartsch, Kiran G R Kumar, Damion Lambert, Sara Mohammadi Mahvash, Thalia Rodriguez Garcia, Martin Tran, Thomas Adam, Vikki Revell, Giuseppe Atzori, Lucinda Grainger, Hana Hassanin, James Woolley, Iris Wood-Campar, Janetta Rexha, Sophie Horrocks, Brian Quan, Jessica True, Olga Balazikova, Emily Beale, Vaiva Zarombaite, Lucy Copps, Olivia Knight, Gaganpreet Bangar, Chelsea Mukonda, Jessica Hine, Luke Mallon, Anesha Patel, Ruby Lyall, Pippa Kirby, Mike Law, Andy Kenny
Publikováno v:
BMJ Open, Vol 13, Iss 5 (2023)
Introduction The prevalence of traumatic brain injury (TBI) among older adults is increasing exponentially. The sequelae can be severe in older adults and interact with age-related conditions such as multimorbidity. Despite this, TBI research in olde
Externí odkaz:
https://doaj.org/article/7ac3b4d583fb40b7a0a33329f530b719
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Identifying mechanisms that control molecular function is a significant challenge in pharmaceutical science and molecular engineering. Here, we present a novel projection pursuit recurrent neural network to identify functional mechanisms in
Externí odkaz:
https://doaj.org/article/4188accaacb94107ab6e9dd075021902
Publikováno v:
Biomolecules, Vol 12, Iss 9, p 1246 (2022)
Machine learning (ML) has been an important arsenal in computational biology used to elucidate protein function for decades. With the recent burgeoning of novel ML methods and applications, new ML approaches have been incorporated into many areas of
Externí odkaz:
https://doaj.org/article/a043e053f3cb4c3c9998df84ce914cb6
Autor:
Karen Cawley, Susan E Logue, Adrienne M Gorman, Qingping Zeng, John Patterson, Sanjeev Gupta, Afshin Samali
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e73870 (2013)
Global downregulation of microRNAs (miRNAs) is a common feature of human tumors and has been shown to enhance cancer progression. Several components of the miRNA biogenesis machinery (XPO5, DICER and TRBP) have been shown to act as haploinsufficient
Externí odkaz:
https://doaj.org/article/4145669fbed445928aa3b8e5b672123d
Publikováno v:
Research in Learning Technology, Vol 10, Iss 1 (2002)
A vital aspect of any professional education is the opportunity for students to engage in meaningful practical experiences. In pre-service teacher education in Australia, this vital teaching practice component has undergone challenges in recent years
Externí odkaz:
https://doaj.org/article/a57dc0cf672e41da982c2fa66f949a17
Akademický článek
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Autor:
Jade Chow, John Patterson
Oxford Assess and Progress is a new and unique revision resource for medical students. Written and edited by subject and assessment experts the series provides a wealt of popular assessment questions and extra features to be truly fit for purpose and
Publikováno v:
World Journal of Hepatology. 15:282-288
Publikováno v:
ACS Omega. 7:9196-9205