Zobrazeno 1 - 10
of 240
pro vyhledávání: '"John P. Wolfe"'
Autor:
Lisa Bradshaw, Julianne Vernon, Thomas Schmidt, Timothy James, Jianzhi Zhang, Hilary Archbold, Kenneth Cadigan, John P. Wolfe, Deborah Goldberg
Publikováno v:
Journal of Microbiology & Biology Education, Vol 24, Iss 3 (2023)
ABSTRACTResearch has shown that undergraduate research experiences can have substantive effects on retaining students in science, technology, engineering and mathematics (STEM). However, it is impossible to provide individual research experiences for
Externí odkaz:
https://doaj.org/article/b50da5de433a44b1af3709474e0842f7
Autor:
Jacqueline E. Hunter, Caitlyn M. Molony, Jessica H. Bagel, Patricia A. O’Donnell, Stephen G. Kaler, John H. Wolfe
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 26, Iss , Pp 384-393 (2022)
Multiple studies have examined the transduction characteristics of different AAV serotypes in the mouse brain, where they can exhibit significantly different patterns of transduction. The pattern of transduction also varies with the route of administ
Externí odkaz:
https://doaj.org/article/0a1656607a9844baa60b21f7aa32d924
Publikováno v:
Organic Letters. 25:3245-3248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cd42d67b4acda41fd0195d8eaabb9ac
https://doi.org/10.1021/acs.orglett.3c00954
https://doi.org/10.1021/acs.orglett.3c00954
Publikováno v:
Organic Letters. 25:2767-2770
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c0671d6a772d0d83a588c95b3d2273a
https://doi.org/10.1021/acs.orglett.3c00571
https://doi.org/10.1021/acs.orglett.3c00571
Autor:
Evan C. Bornowski, James H. Shepich, Paige M. Carpenter, Derick R. White, Jessica E. Hatt, John P. Wolfe
Publikováno v:
Organic letters. 24(44)
Regiodivergent palladium-catalyzed alkene difunctionalization reactions between diethyl malonate and 1,5-dienes bearing a triflate group at C2 are described. Use of tris(2,4-di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b1f23bdf92795ab873f54b46ad3b921
https://pubmed.ncbi.nlm.nih.gov/36315977
https://pubmed.ncbi.nlm.nih.gov/36315977
Publikováno v:
Stem Cell Reports, Vol 4, Iss 5, Pp 835-846 (2015)
Neural stem cell (NSC) transplantation is a promising strategy for delivering therapeutic proteins in the brain. We evaluated a complete process of ex vivo gene therapy using human induced pluripotent stem cell (iPSC)-derived NSC transplants in a wel
Externí odkaz:
https://doaj.org/article/8d4c748cdb3747fc87c6c4ee19663a21
Publikováno v:
The Journal of Organic Chemistry. 86:11378-11387
This article describes continued studies on Pd-catalyzed alkene diamination reactions between N-allylguanidines or ureas and O-benzoylhydroxylamine derivatives, which serve as N-centered electrophiles. The transformations generate cyclic guanidines a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9296fb7bee4c207b34c78bebc8f7cbad
https://doi.org/10.1021/acs.joc.1c00877
https://doi.org/10.1021/acs.joc.1c00877
Autor:
Wenpei Liu, Gerald Griffin, Trena Clarke, Michael K Parente, Rita J Valentino, John H Wolfe, Nigel W Fraser
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)
Genetic diseases of the brain usually have pathologic lesions distributed throughout, thus requiring global correction. Herpes simplex virus-1 (HSV-1) vectors may be especially useful for gene delivery in these disorders since they can spread trans-s
Externí odkaz:
https://doaj.org/article/6b25cb0a96534986944aec5ede82ecf5
Publikováno v:
J Org Chem
This article describes continued studies on Pd-catalyzed alkene diamination reactions between N-allylguanidines or ureas and O-benzoylhydroxylamine derivatives, which serve as N-centered electrophiles. The transformations generate cyclic guanidines a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d9ed756d84605d7dcbd5b89d8e6b23e
https://pubmed.ncbi.nlm.nih.gov/34344155
https://pubmed.ncbi.nlm.nih.gov/34344155
Publikováno v:
Org Process Res Dev
Palladium-catalyzed alkene difunctionalization reactions between alkenes bearing tethered aryl or alkenyl triflates and enolate nucleophiles are described. The transformations form two C–C bonds, a ring, and up to two stereocenters, while producing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc447b10ef93fc58501e9aca3057fbd6
https://doi.org/10.1021/acs.oprd.9b00248
https://doi.org/10.1021/acs.oprd.9b00248