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of 4
pro vyhledávání: '"John P. Valenta"'
Autor:
Rueben A. Gonzales, John P. Valenta
Publikováno v:
Alcoholism: Clinical and Experimental Research. 40:187-195
Background Among the evidence implicating neuroimmune signaling in alcohol use disorders are increased levels of the chemokine monocyte chemoattractant protein-1 (MCP-1) in the brains of human alcoholics and animal models of alcohol abuse. However, i
Autor:
Martin O. Job, John P. Valenta, Elaina C. Howard, Rueben A. Gonzales, Regina A. Mangieri, Christina J. Schier
Publikováno v:
Psychopharmacology. 228:389-400
Naltrexone, a non-selective opioid antagonist, decreases the euphoria and positive subjective responses to alcohol in heavy drinkers. It has been proposed that the μ-opioid receptor plays a role in ethanol reinforcement through modulation of ethanol
Autor:
Michael D. DiGianvittorio, Keita Ishiwari, John D. Salamone, Lisa J. Madson, Christa E. Müller, Mercè Correa, Susana Mingote, Lauren E. Frank, Andrew M. Farrar, John P. Valenta, Jörg Hockemeyer
Publikováno v:
Behavioural Brain Research. 178:190-199
There is considerable evidence of interactions between adenosine A2A receptors and dopamine D2 receptors in striatal areas, and antagonists of the A2A receptor have been shown to reverse the motor effects of DA antagonists in animal models. The D2 an
Autor:
Ian F. Parney, Dong W. Lee, Raquel Sitcheran, Dhivya Ramakrishnan, John P Valenta, Kayla J. Bayless
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57489 (2013)
PLoS ONE
PLoS ONE
High-grade gliomas, such as glioblastomas (GBMs), are very aggressive, invasive brain tumors with low patient survival rates. The recent identification of distinct glioma tumor subtypes offers the potential for understanding disease pathogenesis, res