Inhibition and Reversal of Microbial Attachment by an Antibody with Parasteric Activity against the FimH Adhesin of Uropathogenic E. coli.

Autor: Dagmara I Kisiela, Hovhannes Avagyan, Della Friend, Aachal Jalan, Shivani Gupta, Gianluca Interlandi, Yan Liu, Veronika Tchesnokova, Victoria B Rodriguez, John P Sumida, Roland K Strong, Xue-Ru Wu, Wendy E Thomas, Evgeni V Sokurenko

Publikováno v: PLoS Pathogens, Vol 11, Iss 5, p e1004857 (2015)

Attachment proteins from the surface of eukaryotic cells, bacteria and viruses are critical receptors in cell adhesion or signaling and are primary targets for the development of vaccines and therapeutic antibodies. It is proposed that the ligand-bin

Externí odkaz: https://doaj.org/article/62ac6508696e4e46905fadab9acd7553

The nucleotide exchange factor Ric-8A is a chaperone for the conformationally dynamic nucleotide-free state of Gαi1.

Autor: Celestine J Thomas, Klára Briknarová, Jonathan K Hilmer, Navid Movahed, Brian Bothner, John P Sumida, Gregory G Tall, Stephen R Sprang

Publikováno v: PLoS ONE, Vol 6, Iss 8, p e23197 (2011)

Heterotrimeric G protein α subunits are activated upon exchange of GDP for GTP at the nucleotide binding site of Gα, catalyzed by guanine nucleotide exchange factors (GEFs). In addition to transmembrane G protein-coupled receptors (GPCRs), which ac

Externí odkaz: https://doaj.org/article/8e8b8b682bd141db9e6d1bb49efc6327

Membrane Interactions, Ligand-Dependent Dynamics, and Stability of Cytochrome P4503A4 in Lipid Nanodiscs

Autor: Wynton D. McClary, Miklos Guttman, Hyewon Kwon, John P. Sumida, Michelle Redhair, Nicholas A. Treuheit, William M. Atkins

Publikováno v: Biochemistry. 55(7)

Membrane-bound cytochrome P4503A4 (CYP3A4) is the major source of enzymatic drug metabolism. Although several structural models of CYP3A4 in various ligand complexes are available, none includes a lipid bilayer. Details of the effects of the membrane

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60432a81a01d4d9812c84cdddb788576
https://pubmed.ncbi.nlm.nih.gov/26814638

A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation

Autor: Tomas Obsil, Helmut Cölfen, Anna Modrak-Wójcik, José García de la Torre, Caitlin I. Stoddard, Ute Curth, Thomas M. Laue, Geeta J. Narlikar, Szu Huan Wang, Carlos Alfonso, Carlos R. Escalante, Jia Ma, Gali Prag, Masanori Noda, Katherine Stott, Klaus Richter, Carrie A. May, Peter Schuck, Fumio Arisaka, Edward Eisenstein, Stephen J. Perkins, Ilan Attali, John P. Sumida, Catherine T. Chaton, Erby E. Perdue, Davis Jose, David Staunton, Matthew A. Perugini, Jin Ku Park, Amanda Nourse, Peter E. Prevelige, Craig L. Peterson, Norbert Mücke, Satoru Unzai, Peter D. Pawelek, Jayesh Gor, Arne C. Rufer, Rose Rosenberg, Hauke Lilie, Martin G. Peverelli, Yee-Foong Mok, Martin Wolff, Jacinta M. Wubben, Luitgard Nagel-Steger, Peter H. von Hippel, Karolin Luger, Edward Wright, Holger M. Strauss, Lenka Rezabkova, Agnieszka Bzowska, Aline Le Roy, Steven E. Weitzel, Jonathan B. Chaires, Elena Krayukhina, Donald F. Becker, Alexandra S. Solovyova, Alison E. Ringel, Chad A. Brautigam, Dalibor Kosek, David J. Scott, Kimberly A. Crowley, Cynthia Wolberger, Soon-Jong Kim, Adam G. Larson, Leslie E. Eisele, Susumu Uchiyama, Gregory J. Bedwell, Javier Seravalli, Bertrand Raynal, Ron M. Finn, Hyewon Kwon, Tabot M. D. Besong, Marina Bakhtina, Ahmet Bekdemir, Shu-Chuan Jao, Bashkim Kokona, Catherine Birck, Roman H. Szczepanowski, Andrew B. Herr, Christine Wandrey, Stephen E. Harding, Daniel D Krzizike, David L. Bain, José G. Hernández Cifre, Grzegorz Piszczek, Renjie Song, Stephan Uebel, Tina Daviter, Damien Hall, Debra M. Eckert, Patrick England, Ingrid Tessmer, Eric Kusznir, Ernest L. Maynard, William L. Dean, Werner Streicher, Christine Ebel, Anna Vitlin Gruber, Beata Wielgus-Kutrowska, Rodolfo Ghirlando, Yu Sung Wu, Ana I. Díez, Olwyn Byron, Robert Fairman, William Brennerman, Henning Gustafsson, Richard Stefan Isaac, Wolfgang Fischle, Elizabeth E. Howell, Ronald T. Toth, Sarah G. Swygert, Ashutosh Tripathy, Arthur J. Rowe, Chad K. Park, Jeffrey A. Fagan, Keith D. Connaghan, Huaying Zhao, Jack A. Kornblatt, Andrew P. Leech, Juan Román Luque-Ortega

Publikováno v: BASE-Bielefeld Academic Search Engine
PLOS One
PLoS ONE
PLoS ONE, Public Library of Science, 2015, 10 (5), pp.e0126420. ⟨10.1371/journal.pone.0126420⟩
PLoS ONE, 2015, 10 (5), pp.e0126420. ⟨10.1371/journal.pone.0126420⟩
Digital.CSIC. Repositorio Institucional del CSIC
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PLOS ONE
PLoS ONE, Vol 10, Iss 5, p e0126420 (2015)

30 p.-14 fig. Zhao, Huaying, et alt.
Analytical ultracentrifugation (AUC) is a first principles based method to determine absolute sedimentation coefficients and buoyant molar masses of macromolecules and their complexes, reporting on their size

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c75a0742649141dce7eccfdea022baa
http://hdl.handle.net/10261/120910

Increasing the Yield of Photoinduced Charge Separation through Parallel Electron Transfer Pathways

Autor: Devens Gust, Ana L. Moore, John P. Sumida, Nyangenya I. Maniga, Simon G. Stone, Thomas A. Moore

Publikováno v: Journal of Porphyrins and Phthalocyanines. :32-44

A strategy for increasing the yield of long-lived photoinduced charge separation in artificial photosynthetic reaction centers which is based on multiple electron transfer pathways operating in parallel has been investigated. Excitation of the porphy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::301a7e1d124b031bb9ac571bf1a67c4a
https://doi.org/10.1002/(sici)1099-1409(199901)3:1<32::aid-jpp99>3.0.co